Browse > Article
http://dx.doi.org/10.5999/aps.2012.39.5.497

Reliability of Reconstructed Breast Flap after Chemotherapy and Radiotherapy in Immediate Breast Reconstruction  

Lee, Keun-Cheol (Department of Plastic and Reconstructive Surgery, Dong-A University College of Medicine)
Kim, Tae-Heon (Department of Plastic and Reconstructive Surgery, Dong-A University College of Medicine)
Park, Su-Sung (Department of Plastic and Reconstructive Surgery, Dong-A University College of Medicine)
Kim, Min-Su (Department of Plastic and Reconstructive Surgery, Dong-A University College of Medicine)
Kim, Myung-Hoon (Department of Plastic and Reconstructive Surgery, Dong-A University College of Medicine)
Kim, Seok-Kwun (Department of Plastic and Reconstructive Surgery, Dong-A University College of Medicine)
Cho, Se-Heon (Department of General Surgery, Dong-A University College of Medicine)
Lee, Mi-Ri (Department of General Surgery, Dong-A University College of Medicine)
Lee, Jin-Hwa (Department of Radiology, Dong-A University College of Medicine)
Lee, Hyung-Sik (Department of Radiation Oncology, Dong-A University College of Medicine)
Kim, Dae-Cheol (Department of Pathology, Dong-A University College of Medicine)
Publication Information
Archives of Plastic Surgery / v.39, no.5, 2012 , pp. 497-503 More about this Journal
Abstract
Background Postmastectomy adjuvant therapy is used to prevent locoregional recurrence and improve overall breast cancer specific survival rates. However, it can adversely affect the cosmetic results of reconstruction. Therefore, the authors examined flap stability and patients' satisfaction with immediate breast reconstruction after adjuvant therapy. Methods We retrospectively reviewed the medical records of 204 patients from January 2006 to November 2011. For complication rates, the authors categorized the patients who underwent the immediate breast reconstruction into 4 groups: adjuvant chemotherapy and radiotherapy group, adjuvant chemotherapy only group, adjuvant radiotherapy only group, and the group that did not undergo adjuvant therapy. For comparison of patients' satisfaction, the study was performed with an additional 16 patients who had undergone delayed breast reconstruction. Results Regarding complication rates, the group that had undergone adjuvant therapy showed no significant difference compared to the group that did not undergo adjuvant therapy. In evaluating the patients' satisfaction, there was no significant difference. Conclusions Even after adjuvant therapy, immediate breast reconstruction showed good results with respect to flap stability and patients' satisfaction. Immediate breast reconstruction and adjuvant therapy is a safe and useful option for breast cancer patients.
Keywords
Drug therapy; Radiotherapy; Breast; Surgical flaps;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Buchholz TA, Strom EA, Perkins GH, et al. Controversies regarding the use of radiation after mastectomy in breast cancer. Oncologist 2002;7:539-46.   DOI   ScienceOn
2 Yi A, Kim HH, Shin HJ, et al. Radiation-induced complications after breast cancer radiation therapy: a pictorial review of multimodality imaging findings. Korean J Radiol 2009;10:496-507.   DOI   ScienceOn
3 Senkus-Konefka E, Jassem J. Complications of breast-cancer radiotherapy. Clin Oncol (R Coll Radiol) 2006;18:229-35.   DOI   ScienceOn
4 Senkus-Konefka E, Welnicka-Jaskiewicz M, Jaskiewicz J, et al. Radiotherapy for breast cancer in patients undergoing breast reconstruction or augmentation. Cancer Treat Rev 2004;30:671-82.   DOI   ScienceOn
5 Alderman AK, Collins ED, Schott A, et al. The impact of breast reconstruction on the delivery of chemotherapy. Cancer 2010;116:1791-800.   DOI   ScienceOn
6 Spear SL, Ducic I, Low M, et al. The effect of radiation on pedicled TRAM flap breast reconstruction: outcomes and implications. Plast Reconstr Surg 2005;115:84-95.
7 Kronowitz SJ, Robb GL. Radiation therapy and breast reconstruction: a critical review of the literature. Plast Reconstr Surg 2009;124:395-408.   DOI   ScienceOn
8 Lee BT, T AA, Colakoglu S, et al. Postmastectomy radiation therapy and breast reconstruction: an analysis of complications and patient satisfaction. Ann Plast Surg 2010;64:679-83.
9 Jagsi R, Abrahamse P, Morrow M, et al. Postmastectomy radiotherapy for breast cancer: patterns, correlates, communication, and insights into the decision process. Cancer 2009;115:1185-93.   DOI   ScienceOn
10 Paulson RL, Chang FC, Helmer SD. Kansas surgeons' attitudes toward immediate breast reconstruction: a statewide survey. Am J Surg 1994;168:543-6.   DOI   ScienceOn
11 Wellisch DK, Schain WS, Noone RB, et al. Psychosocialcorrelates of immediate versus delayed reconstruction of the breast. Plast Reconstr Surg 1985;76:713-8.   DOI   ScienceOn
12 Zhang YJ, Sun GQ, Chen J, et al. Postmastectomy locoregional recurrence and survival in early stage breast cancer patients with one to three axillary lymph node metastases. Ai Zheng 2009;28:395-401.