Browse > Article
http://dx.doi.org/10.14401/KASMED.2020.27.2.56

The Effect of Continuous Positive Pressure Therapy for Obstructive Sleep Apnea on Quality of Life : A Single-Institution Study  

Shin, Hyun Suk (Department of Neuropsychiatry, Presbyterian Medical Center-Jesus Hospital)
Choi, Mal Rye (Department of Neuropsychiatry, Presbyterian Medical Center-Jesus Hospital)
Kim, Shin il (Department of Neuropsychiatry, Presbyterian Medical Center-Jesus Hospital)
Hong, Se Yeon (Department of Neuropsychiatry, Presbyterian Medical Center-Jesus Hospital)
Eun, Hun Jeong (Department of Neuropsychiatry, Presbyterian Medical Center-Jesus Hospital)
Publication Information
Sleep Medicine and Psychophysiology / v.27, no.2, 2020 , pp. 56-66 More about this Journal
Abstract
Objectives: In this study, the clinical characteristics of OSA patients and the quality of life before and after CPAP use were compared to determine the degree of improvement in quality of life according to CPAP use. Methods: Age, sex, height, weight, body mass index, Epworth Sleepiness Scale, Modified Mallampatti Score, Montreal Cognitive Assessment-Korean, and Pittsburgh Sleep Quality Index were compared between men and women through medical records. To understand the degree of improvement in quality of life resulting from use of CPAP, a personal telephone call was made to compare the VAS scores for quality of life before and after CPAP use. Results: In height (HT) (Z = -4.525, p < 0.001), weight (BW) (Z = -2.844, p < 0.05), sleep quality (PSQI) (Z = -2.671, p < 0.05), and arousal index (AI) (Z = -2.105, p < 0.05), there was a difference between men and women (p < 0.05). There was no difference in the remaining variables. Cross-analysis (Chi-square test) confirmed a difference between severity and sex of OSA. It has been found that there is no statistically significant order in size according to level-specific severity of OSA for PreCPAP QOL, PostCPAP QOL, CPAPUse Months, and CPAP4Hr/d (%) (p > 0.05). The difference between AHI before and after CPAP was 36.48 ± 21.54 (t = 11.609, p < 0.001) and the difference between QOL before and after CPAP was -25.43 ± 22.06 (t = -7.901, p < 0.001), both of which were significant (p < 0.001). Conclusion: Among OSA patients, there were differences in height (HT), weight (BW), sleep quality (PSQI), arousal index (AI), and severity of OSA between men and women, but the quality of life before and after CPAP was different. However, there was no difference between men and women in quality of life before and after CPAP. In addition, quality of life in OSA patients improved after using CPAP.
Keywords
Continuous Positive Airway Pressure; Obstructive Sleep Apnea; Quality of Life; Sex difference;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
연도 인용수 순위
1 Alison W, Sahisha K, Dinesh R, Jeffery A, Holger W. Gender differences in obstructive sleep apnea. SM Group Open Access eBooks 2016:1-11.
2 Amatoury J, Jordan AS, Toson B, Nguyen C, Wellman A, Eckert DJ. New insights into the timing and potential mechanisms of respiratory-induced cortical arousals in obstructive sleep apnea. Sleep 2018;41:zsy160.
3 American Academy of Sleep Medicine. International classification of sleep disorders. 3rd ed 2014 American Academy of Sleep Medicine Darien, IL
4 American Academy of Sleep Medicine Task Force. Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. Sleep 1999;22:667-689.   DOI
5 Ancoli-Israel S, Kripke DF, Klauber MR, Mason WJ, Fell R, Kaplan O. Sleep-disordered breathing in community-dwelling elderly. Sleep 1991;14:486-495.   DOI
6 Armon C, Johnson K, Roy A, Nowack W. Polysomnography. Medscape;2016.
7 Batool-Anwar S, Goodwin JL, Kushida CA, Walsh JA, Simon RD, Nichols DA, et al. Impact of continuous positive airway pressure (CPAP) on quality of life in patients with obstructive sleep apnea (OSA). J Sleep Res 2016;25:731-738.   DOI
8 Becker HF, Jerrentrup A, Ploch T, Grote L, Penzel T, Sullivan CE, et al. Effect of nasal continuous positive airway pressure treatment on blood pressure in patients with obstructive sleep apnea. Circulation 2003;107:68-73.   DOI
9 Folstein MF, Folstein SE, McHugh PR. "Mini-mental state": a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189-198.   DOI
10 Buysse DJ, Reynolds III CF, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Research 1989;28: 193-213.   DOI
11 Choi SJ. Complications of obstructive sleep apnea. The Korean Journal of Medicine 2015;89:13-20. Published online July 1, 2015.   DOI
12 Cho YW, Lee JH, Son HK, Lee SH, Shin C, Johns MW. The reliability and validity of the Korean version of the Epworth sleepiness scale. Sleep Breath 2011;15:377-384.   DOI
13 Douglas Neil J. Clinician's guide to sleep medicine. London: Hodder-Headline Group;2002.
14 Elsobki A, Cahali MB, Kahwagi M. LwPTL: a novel classification for upper airway collapse in sleep endoscopies. Braz J Otorhinolaryngol 2019;85:379-387.   DOI
15 Epstein L, Kristo D, Strollo P, Friedman N, Malhotra A, Patil S, et al. Clinical guideline for the evaluation, management and longterm care of obstructive sleep apnea in adults. J Clin Sleep Med 2009;5:263-276.   DOI
16 Flemons WW, Tsai W. Quality of life consequences of sleep-disordered breathing. J Allergy Clin Immunol 1997;99:S750-S756.
17 Heinzer R, Vat S, Marques-Vidal P, Marti-Soler H, Andries D, Tobback N, et al. Prevalence of sleep-disordered breathing in the general population: the HypnoLaus study. Lancet Respir Med 2015;3:310-318.   DOI
18 Flemons WW, Reimer MA. Development of a disease-specific healthrelated quality of life questionnaire for sleep apnea. Am J Respir Crit Care Med 1998;158:494-503.   DOI
19 Flemons WW, Reimer MA. Measurement properties of the Calgary sleep apnea quality of life index. Am J Respir Crit Care Med 2002;165:159-164.   DOI
20 Gould D, Kelly D, Goldstone L, Gammon J. Visual Analogue Scale (VAS). Journal of Clinical Nursing 2001;10:697-706.   DOI
21 Ibanez V, Silva J, Cauli O. A survey on sleep assessment methods. PeerJ 2018;6:e4849.   DOI
22 Isidoro SI, Salvaggio A, Bue AL, Romano S, Marrone O, Insalaco G. Immediate effect of CPAP titration on perceived health related quality of life: a prospective observational study. BMC Pulm Med 2016;16:172.   DOI
23 Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep 1991;14:540-545.   DOI
24 Johns MW, Hocking B. Daytime sleepiness and sleep habits of Australian workers. Sleep 1997;20:844-847.   DOI
25 Johns MW. Reliability and factor analysis of the Epworth Sleepiness Scale. Sleep 1992;15:376-381.   DOI
26 Jung YK. The utility of Montreal Cognitive Assessment-Korean version for the detection of Amnestic Mild Cognitive Impairment (master's thesis). Graduate school, Chonnam National University 2010.
27 Kapur VK, Auckley DH, Chowdhuri S, Kuhlmann DC, Mehra R, Ramar K, et al. Clinical practice guideline for diagnostic testing for adult obstructive sleep apnea: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med 2017;13:479-504.   DOI
28 Kim JK, In KH, Kim JH, You SH, Kang KH, Shim JJ, et al. Prevalence of sleep-disordered breathing in middle-aged Korean men and women. Am J Respir Crit Care Med 2004;170:1108-1113.   DOI
29 Katsantonis GP, Moss K, Miyazaki S, Walsh J. Determining the site of airway collapse in obstructive sleep apnea with airway pressure monitoring. Laryngoscope 1993;103:1126-1131.
30 Keele KD. The pain chart. The Lancet 1948;2:6-8.   DOI
31 Ko HE, Kim JW, Kim HD, Jang YS, Chung HA. Construction validity of the MoCA-K to MMSE-K, LOTCA-G in the Community living Elderly. Journal of the Korea Academia-Industrial cooperation Society 2013;14:312-320.   DOI
32 Lin CM, Davidson TM, Ancoli-Israel S. Gender differences in obstructive sleep apnea and treatment implications. Sleep Med 2008;12:481-496.   DOI
33 Lozo T, Komnenov D, Badr MS, Mateika JH. Sex differences in sleep disordered breathing in adults. Respir Physiol Neurobiol 2017;245:65-75.   DOI
34 Mallampati SR, Gatt SP, Gugino LD, Desai SP, Waraksa B, Freiberger D, et al. A clinical sign to predict difficult tracheal intubation; a prospective study. Canadian Anaesthetists' Society Journal 1985;32:429-434.   DOI
35 Min SK, Lee CI, Kim KI, Suh SY. Kim DK. Development of Korean Version of WHO Quality of Life Scale Abbreviated Version (WHOQOL-BREF). J Korean Neuropsychiatr Assoc 2000;3: 571-579.
36 Morgenthaler TI, Aurora RN, Brown T, Zak R, Alessi C, Boehlecke B, et al. Practice parameters for the use of autotitrating continuous positive airway pressure devices for titrating pressures and treating adult patients with obstructive sleep apnea syndrome: an update for 2007. An American Academy of Sleep Medicine report. Sleep 2008;31:141-147.   DOI
37 Nolen-Hoeksema S, Larson J, Grayson C. Explaining the gender difference in depressive symptoms. J Pers So Psychol 1999;77: 1061-1072.   DOI
38 Popovic RM, White DP. Influence of gender on waking genioglossal electromyogram and upper airway resistance. Am J Respir Crit Care Med 1995;152:725-731.   DOI
39 Park KS, Chang JH, Kang EW. Effects of 12 months of continuous positive airway pressure therapy on cognitive function, sleep, mood, and health-related quality of life in a peritoneal dialysis patient with obstructive sleep apnea. Kidney Res Clin Pract 2018; 37:89.   DOI
40 Pavwoski P, Shelgikar AV. Treatment options for obstructive sleep apnea. Neurology: Clinical Practice 2017;7:77-85.   DOI
41 Phillipson EA, Sullivan CE. Arousal: the forgotten response to respiratory stimuli. American Lung Association;1978.
42 Quintana-Gallego E, Carmona-Bernal C, Capote F, Sanchez-Armengol A, Botebol-Benhamou G, Polo-Padillo J, et al. Gender differences in obstructive sleep apnea syndrome: a clinical study of 1166 patients. Respir Med 2004;98:984-989.   DOI
43 Richard BB, Stuart FQ, Alexander RA, Marietta LB, Lourdes D, Susan MH. et al. The AASM Manual for the Scoring of Sleep and Associated Events-Rules, Terminology and Technical Specifications. Version 2.6, American Academy of Sleep Medicine; 2020
44 Ruehland WR, Rochfored PD, O'Donoghue FJ, Pierce RJ, Singh P, Thorton AT. The new AASM criteria for scoring hypopneas: impact on the apnea hypopnea index. Sleep 2009;32:150-157.   DOI
45 Ryoo EN, Park KS. Validity, reliability and efficiency of pain self-report scale in elderly with dementia. Korean J Adult Nurs 2011; 2:111-122.
46 Sutherland K, Vanderveken OM, Tsuda H, Marklund M, Gagnadoux F, Kushida CA, et al. Oral appliance treatment for obstructive sleep apnea: an update. J Clin Sleep Med 2014;10:215-227.   DOI
47 Nutt D, Wilson S, Paterson L. Sleep disorders as core symprom of depression. Dialogue Clin Neurosci 2008;10:329-336.   DOI
48 Samsoon G, Young J. Difficult tracheal intubation: a retrospective study. Anaesthesia 1987;42:487-490.   DOI
49 Song SK, Song YJ, Park HG, Kim JI, Cho SD, Ji JY, et al. Therapeutic Outcome of primary snoring and mild obstructive sleep apnea and clinical suggestion for treatment approaches. Korean J Otorhinolaryngol-Head Neck Surg 2019;62:102-107.   DOI