Browse > Article
http://dx.doi.org/10.14401/KASMED.2017.24.1.19

Obstructive Sleep Apnea in Interstitial Lung Disease  

Kim, Shin Bum (Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, College of Medicine, The Catholic University of Korea)
Lee, Sang Haak (Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, College of Medicine, The Catholic University of Korea)
Kang, Hyeon Hui (Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, College of Medicine, The Catholic University of Korea)
Publication Information
Sleep Medicine and Psychophysiology / v.24, no.1, 2017 , pp. 19-23 More about this Journal
Abstract
Obstructive sleep apnea is a common disorder in which respiratory flow decreases or disappears despite respiratory effort due to occlusion of the upper respiratory tract during sleep. Oxidative stress and systemic inflammatory reaction induced by the obstruction cause complications such as hypertension, coronary artery disease, and diabetes and increase cancer incidence. Furthermore, in patients with interstitial lung disease, obstructive sleep apnea has a very high prevalence and is thought to have a close pathophysiological and clinical correlation. In other words, obstructive sleep apnea could be the cause or a complication of interstitial lung disease ; when these two afflictions coexist, the prognosis of the patient is worse. In patients with interstitial lung disease with obstructive sleep apnea, CPAP treatment significantly improved sleep and quality of life, as well as improved morbidity and mortality in a recent study. Therefore, early diagnosis and treatment of obstructive sleep apnea in patients with interstitial lung disease are very important, and additional studies designed to include patients with idiopathic pulmonary fibrosis as well as patients with advanced interstitial lung disease should be performed.
Keywords
Obstructive sleep apnea; Interstitial lung disease; Sleep disorder; CPAP treatment;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Pihtili A, Bingol Z, Kiyan E, Cuhadaroglu C, Issever H, Gulbaran Z. Obstructive sleep apnea is common in patients with interstitial lung disease. Sleep Breath 2013;17:1281-1288.   DOI
2 Prabhaker NR, Kumar GK. Oxidative stress in the systemic and cellular responses to intermittent hypoxia. Biol Chem 2004;385: 217-221.
3 Sajkov D, McEvoy RD. Obstructive sleep apnea and pulmonary hypertension. Prog Cardiovasc Dis 2009;51:363-370.   DOI
4 Series F, Cormier Y, Lampron N, La Forge J. Increasing the functional residual capacity may reverse obstructive sleep apnea. Sleep 1988;11:349-353.
5 Tuleta I, Stockigt F, Juergens UR, Pizarro C, Schrickel JW, Kristiansen G, et al. Intermittent Hypoxia Contributes to the Lung Damage by Increased Oxidative Stress, Inflammation, and Disbalance in Protease/Antiprotease System. Lung 2016;194:1015-1020.   DOI
6 Van de Graaff WB. Thoracic influence on upper airway patency. J Appl Physiol 1988;65:2124-2131.   DOI
7 Van de Graaff WB. Thoracic traction on the trachea: mechanisms and magnitude. J Appl Physiol 1991;70:1328-1363.   DOI
8 Ward PA. Oxidative stress: acute and progressive lung injury. Ann N Y Acad Sci 2010;1203:53-59.   DOI
9 White DP. Pathogenesis of obstructive and central sleep apnea. Am J Respir Crit Care Med 2005;172:1363-1370.   DOI
10 Younes M. Role of respiratory control mechanisms in the pathogenesis of obstructive sleep disorders. J Appl Physiol (1985) 2008; 105:1389-1405.   DOI
11 Aydogdu M, Ciftci B, Guven S, Ulukavak CT, Erdogan Y. Assessment of sleep with polysomnography in patients with interstitial lung disease. Tuberk Toraks 2006;54:213-221.
12 Campen MJ, Shimoda LA, O'Donnell CP. Acute and chronic cardiovascular effects of intermittent hypoxia in C57BL/6J mice. J Appl Physiol 2005;99:2028-2035.   DOI
13 Corte TJ, Wort SJ, Gatzoulis MA, Macdonald P, Hansell DM, Wells AU. Pulmonary vascular resistance predicts early mortality in patients with diffuse fibrotic lung disease and suspected pulmonary hypertension. Thorax 2009;64:883-888.   DOI
14 Corte TJ, Wort SJ, Talbot S, Macdonald PM, Hansel DM, Polkey M, et al. Elevated nocturnal desaturation index predicts mortality in interstitial lung disease. Sarcoidosis Vasc Diffuse Lung Dis 2012;29;41-50.
15 Epstein LJ, Kristo D, Strollo PJ Jr, Friedman N, Malhotra A, Patil SP, et al. Clinical guideline for the evaluation, management and longterm care of obstructive sleep apnea in adults. J Clin Sleep Med 2009;5: 263-276.
16 Kliment CR, Oury TD. Oxidative stress, extracellular matrix targets, and idiopathic pulmonary fibrosis. Free Radic Biol Med 2010; 49:707-717.   DOI
17 Kolilekas L, Manali E, Vlami KA, Lyberopoulos P, Triantafillidou C, Kagouridis K, et al. Sleep oxygen desaturation predicts survival in idiopathic pulmonary fibrosis. J Clin Sleep Med 2013; 9:593-601.
18 Lancaster LH, Mason WR, Parnell JA, Rice TW, Loyd JE, Milstone AP, et al. Obstructive sleep apnea is common in idiopathic pulmonary fibrosis. Chest 2009;136:772-778.   DOI
19 Marcus NJ, Li YL, Bird CE, Schultz HD, Morgan BJ. Chronic intermittent hypoxia augments chemoreflex control of sympathetic activity: role of the angiotensin II type 1 receptor. Respir Physiol Neurobiol 2010;171:36-45.   DOI
20 Mermigkis C, Chapman J, Golish J, Mermigkis D, Budur K, Kopanakis A, et al. Sleep-related breathing disorders in patients with idiopathic pulmonary fibrosis. Lung 2007;185:173-178.   DOI
21 Nadrous HF, Pellikka PA, Krowka MJ, Swanson KL, Chaowalit N, Decker PA, et al. Pulmonary hypertension in patients with idiopathic pulmonary fibrosis. Chest 2005;128:2393-2399.   DOI
22 Heinzer RC, Stanchina ML, Malhotra A, Fogel RB, Patel SR, Jordan AS, Schory K, et al. Lung volume and continuous positive airway pressure requirements in obstructive sleep apnea. Am J Respir Crit Care Med 2005;172:114-117.   DOI
23 Kim J, In K, Kim J, You S, Kang K, Shim J, et al. Prevalence of sleep-disordered, breathing in middle-aged Korean men and women. Am J Respir Crit Care Med 2004;170:1108-1113.   DOI
24 Mermigkis C, Stagaki E, Tryfon S, Schiza S, Amfilochiou A, Polychronopoulos V, et al. How common is sleep-disordered breathing in patients with idiopathic pulmonary fibrosis? Sleep Breath 2010;14:387-390.   DOI
25 Mermigkis C, Bouloukaki I, Antoniou K, Papadogiannis G, Giannarakis I, Varouchakis G, et al Obstructive sleep apnea should be treated in patients with idiopathic pulmonary fibrosis. Sleep Breath 2015;19:385-391.   DOI
26 Moon HS. Influence of sleep-related breathing disorders on changes of cardiovascular function. Sleep Med and Psychophysiol 1998; 4:129-139.
27 Perez-Padilla R, West P, Lertzman M, Kryger MH. Breathing during sleep in patients with interstitial lung disease. Am Rev Respir Dis 1985;132:224-229.