1 |
Kim MS, Kim SH, Jeon D, Kim HY, Lee K (2018) Changes in expression of cytokines in polyhexamethylene guanidine-induced lung fbrosis in mice: comparison of bleomycin-induced lung fbrosis. Toxicology 393:185-192. https://doi.org/10.1016/j.tox.2017.11.017
DOI
|
2 |
Hu HH, Chen DQ, Wang TN, Feng YL, Cao G, Vaziri ND, Zhao YY (2018) New insights into TGF-β/Smad signaling in tissue fbrosis. Chem Biol Interact 292:76-83. https://doi.org/10.1016/j.cbi.2018.07.008
DOI
|
3 |
Zhu X, Kong X, Ma S, Liu R, Li X, Gao S, Ren D, Zheng Y, Tang J (2020) TGFβ/Smad mediated the polyhexamethyleneguanide areosol-induced irreversible pulmonary fbrosis in subchronic inhalation exposure. Inhal Toxicol 32:419-430. https://doi.org/10.1080/08958378.2020.1836091
DOI
|
4 |
Lee H, Park J, Park K (2021) Fibrosis as a result of polyhexamethylene guanide exposure in cultured Statens Seruminstitut Rabbit Cornea (SIRC) cells. Environ Anal Health Toxicol 36:e2021009. https://doi.org/10.5620/eaht.2021009
DOI
|
5 |
Sun S, Park E, Choi Y, Lee H, Ahn BY, Dong M (2016) Development and pre-validation of an in vitro transactivation assay for detection of (anti)androgenic potential compounds using 22Rv1/MMTV cells. Reprod Toxicol 60:156-166. https://doi.org/10.1016/j.reprotox.2016.02.006
DOI
|
6 |
Park J, Lee H, Park K (2019) Eye irritation tests of polyhexamethylene guanidine phosphate (PHMG) and chloromethylisothiazolinone/methylisothiazolinone (CMIT/MIT) using a tissue model of reconstructed human cornea-like epithelium. Environ Health Toxicol 34:e2019004. https://doi.org/10.5620/eht.e2019004
DOI
|
7 |
Lee J, Choi SJ, Jeong JS, Kim SY, Lee SH, Yang MJ, Lee SJ, Shin YJ, Lee K, Jeong EJ, Nam SY, Yu WJ (2021) A humidifer disinfectant biocide, polyhexamethylene guanidine phosphate, inhalation exposure during pregnancy induced toxicities in rats. J Hazard Mater 404:124007. https://doi.org/10.1016/j.jhazmat.2020.124007
DOI
|
8 |
Kim H, Ji K (2019) Exposure to humidifer disinfectants induces developmental efects and disrupts thyroid endocrine systems in zebrafsh larvae. Ecotoxicol Environ Saf 184:109663. https://doi.org/10.1016/j.ecoenv.2019.109663
DOI
|
9 |
OECD (2021) Test guideline no 455, performance-based test guideline for stably transfected transactivation in vitro assays to detect estrogen receptor agonists and antagonists. https://www.oecd.org/chemicalsafety/testing/oecdguidelinesforthetestingofchemicals.htm
|
10 |
Yamasaki K, Takeyoshi M, Yakabe Y, Sawaki M, Imatanaka N, Takatsuki M (2002) Comparison of reporter gene assay and immature rat uterotrophic assay of twenty-three chemicals. Toxicology 170:21-30. https://doi.org/10.1016/s0300-483x(01)00505-4
DOI
|
11 |
Park C, Song H, Choi J, Sim S, Kojima H, Park J, Iida M, Lee Y (2020) The mixture efects of bisphenol derivatives on estrogen receptor and androgen receptor. Environ Pollut 260:114036. https://doi.org/10.1016/j.envpol.2020.114036
DOI
|
12 |
OECD (2020) Test guideline 458. Androgen receptor transactivation assays for detection of androgenic agonist and antagonist activity of chemicals using stably transfected cell lines. https://www.oecd.org/chemicalsafety/testing/oecdguidelinesforthetestingofchemicals.htm
|
13 |
Lee J, Jeong JS, Kim SY, Im WJ, Shin YJ, Lee K, Choi SJ, Heo Y, Jeong EJ, Nam SY, Yu WJ (2019) Reproductive and developmental toxicity screening of polyhexamethylene guanidine phosphate by oral gavage in rats. Regul Toxicol Pharmacol 108:104440. https://doi.org/10.1016/j.yrtph.2019.104440
DOI
|
14 |
Melin VE, Potineni H, Hunt P, Griswold J, Siems B, Werre SR, Hrubec TC (2014) Exposure to common quaternary ammonium disinfectants decreases fertility in mice. Reprod Toxicol 50:163-170. https://doi.org/10.1016/j.reprotox.2014.07.071
DOI
|
15 |
Melin VE, Melin TE, Dessify BJ, Nguyen CT, Shea CS, Hrubec TC (2016) Quaternary ammonium disinfectants cause subfertility in mice by targeting both male and female reproductive processes. Reprod Toxicol 59:159-166. https://doi.org/10.1016/j.reprotox.2015.10.006
DOI
|
16 |
Paek D, Koh Y, Park DU, Cheong HK, Do KH, Lim CM, Hong SJ, Kim YH, Leem JH, Chung KH, Choi YY, Lee JH, Lim SY, Chung EH, Cho YA, Chae EJ, Joh JS, Yoon Y, Lee KH, Choi BY, Gwack J (2015) Nationwide study of humidifer disinfectant lung injury in South Korea 1994-2011. incidence and dose-response relationships. Annals Am Thorac Soc 12:1813-1821. https://doi.org/10.1513/AnnalsATS.201504-221OC
DOI
|
17 |
Park K (2016) An analysis of a humidifer disinfectant case from a toxicological perspective. Environ Health Toxicol 31:e2016013. https://doi.org/10.5620/eht.e2016013
DOI
|
18 |
Lee JH, Lee JH (2017) Humidifer disinfectant-associated specifc diseases should be called together as "humidifer disinfectant syndrome." Environ Health Toxicol 32:e2017017. https://doi.org/10.5620/eht.e2017017
DOI
|
19 |
Kim HR, Hwang GW, Naganuma A, Chung KH (2016) Adverse health efects of humidifer disinfectants in Korea: lung toxicity of polyhexamethylene guanidine phosphate. J Toxicol Sci 41:711-717. https://doi.org/10.2131/jts.41.711
DOI
|
20 |
Lee SJ, Park JH, Lee JY, Jeong YJ, Song JA, Lee KH, Kim DJ (2016) Establishment of a mouse model for pulmonary infammation and fbrosis by intratracheal instillation of polyhexamethyleneguanidine phosphate. J Toxicol Pathol 29:95-102. https://doi.org/10.1293/tox.2015-0067
DOI
|
21 |
Song JA, Kim WJ, Kim YB, Kim BS, Lee KH (2018) Time course of polyhexamethyleneguanidine phosphate-induced lung infammation and fbrosis in mice. Toxicol Appl Pharmacol 345:94-102. https://doi.org/10.1016/j.taap.2018.02.013
DOI
|
22 |
Park DU, Park JH, Yang KW, Park JH, Kwon JH, Oh HB (2020) Properties of polyhexamethylene guanidine (PHMG) associated with fatal lung injury in Korea. Molecules 25:3301-3313. https://doi.org/10.3390/molecules25143301
DOI
|
23 |
Michalikova K, Linhartova L, Ezechias M, Cajthaml T (2018) Assessment of agonistic and antagonistic properties of widely used oral care antimicrobial substances toward steroid estrogenic and androgenic receptors. Chemosphere 217:534-541. https://doi.org/10.1016/j.chemosphere.2018.11.006
DOI
|
24 |
Park DU, Ryu SH, Lim HK, Kim SK, Choi YY, Ahn JJ, Lee E, Hong SB, Do KH, Cho JL, Bae MJ, Shin DC, Paek DM, Hong SJ (2017) Types of household humidifer disinfectant and associated risk of lung injury (HDLI) in South Korea. Sci Total Environ 596-597:53-60. https://doi.org/10.1016/j.scitotenv.2017.04.040
DOI
|
25 |
Cho HJ, Lee SY, Park DU, Ryu SH, Yoon JS, Jung SS, Lee E, Yang SI, Hong SJ (2019) Early-life exposure to humidifier disinfectant determines the prognosis of lung function in children. BMC Pulm Med 19:261-271. https://doi.org/10.1186/s12890-019-1028-y
DOI
|