Evaluation of Estrogenic Activity of Extract from the Herbal Mixture Cynanchum wilfordii Hemsley, Phlomis umbrosa Turczaninow, and Angelica gigas Nakai |
Kim, Se Jong
(College of Pharmacy, Chungnam National University)
Jin, Sun Woo (College of Pharmacy, Chungnam National University) Lee, Gi-Ho (College of Pharmacy, Chungnam National University) Kim, Yong An (College of Pharmacy, Chungnam National University) Jeong, Hye Gwang (College of Pharmacy, Chungnam National University) |
1 | American Medical Association (1992) Guidelines for counseling postmenopausal women about preventive hormone therapy. American College of Physicians. Ann. Intern. Med., 117, 1038-1041. |
2 | Rossouw, J.E., Anderson, G.L., Prentice, R.L., LaCroix, A.Z., Kooperberg, C., Stefanick, M.L., Jackson, R.D., Beresford, S.A., Howard, B.V., Johnson, K.C., Kotchen, J.M. and Ockene, J. (2002) Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA, 288, 321-333. DOI |
3 | National Toxicology Program (2008) Toxicology and carcinogenesis studies of genistein (Cas No. 446-72-0) in Sprague-Dawley rats (feed study). Natl. Toxicol. Program Techn. Rep. Ser., (545), 1-240. |
4 | de Lemos, M.L. (2001) Effects of soy phytoestrogens genistein and daidzein on breast cancer growth. Ann. Pharmacother., 35, 1118-1121. DOI |
5 | Kim, S.N., Li, Y.C., Xu, H.D., Yi, D.G., Kim, M.S., Lee, S.P., Yi, K.T., Lee, J.K., Kim, J.S., Kwon, M.S., Chang, P.S. and Kwak, B.Y. (2008) Phytoestrogenic effects of combined plant extracts on the change of bone metabolismof OVX rats. Korean J. Food Sci. Technol., 40, 316-320. |
6 | Lee, Y.J., Choi, H.I., Kim, Y.C., You, H.K. and Shin, H.S. (2003) Effects of dichloromethane fraction of Phlomidis radix on bone formation in human fetal osteoblasts. J. Korean Acad. Periodontol., 33, 259-269. DOI |
7 | Wong, R.W., Rabie, A.B. and Hagg, E.U. (2007) The effect of crude extract from Radix Dipsaci on bone in mice. Phytother. Res., 21, 596-598. DOI |
8 | Bae, I.Y., Lee, J.Y., Kwak, B.Y. and Lee, H.G. (2011) Estrogenic effects of various extracts from Chamdanggui (Angelica gigas Nakai) and Sogdan (Phlomis umbrosa Turcz) Food Sci. Biotechnol., 20, 1113-1118. DOI |
9 | Lee, K.H., Lee, D.J., Kim, S.M., Je, S.H., Kim, E.K., Han, H.S. and Han, I.K. (2005) Evaluation of effectiveness and safety of natural plants extract (Estromon) on perimenopausal women for 1 year. J. Korean Soc. Menopause, 11, 16-26. |
10 | Chang, A., Kwak, B.Y., Yi, K. and Kim, J.S. (2012) The effect of herbal extract (EstroG-100) on pre-, peri- and post-menopausal women: a randomized double-blind, placebo-controlled study. Phytother. Res., 26, 510-516. DOI |
11 | OECD, Organization for Economic Cooperation and Development. (2009) Ten new test guidelines and six updated test guidelineshave been adopted by council on 7 September. |
12 | Han, E.H., Kim, H.G., Hwang, Y.P., Song, G.Y. and Jeong, H.G. (2010) Prostaglandin E2 induces CYP1B1 expression via ligand-independent activation of the ERalpha pathway in human breast cancer cells. Toxicol. Sci., 114, 204-216. DOI |
13 | Obourn, J.D., Koszewski, N.J. and Notides, A.C. (1993) Hormone- and DNA-binding mechanisms of the recombinant human estrogen receptor. Biochemistry, 32, 6229-6236. DOI |
14 | Kim, C.W., Go, R.E. and Cho, K.C. (2015) Treatment of BG-1 ovarian cancer cells expressing estrogen receptors with lambda-cyhalothrin and cypermethrin caused a partial estrogenicity via an estrogen receptor-dependent pathway. Toxicol. Res., 31, 331-337. DOI |
15 | Hammond, M.E., Hayes, D.F., Dowsett, M., Allred, D.C., Hagerty, K.L., Badve, S., Fitzgibbons, P.L., Francis, G., Goldstein, N.S., Hayes, M., Hicks, D.G., Lester, S., Love, R., Mangu, P.B., McShane, L., Miller, K., Osborne, C.K., Paik, S., Perlmutter, J., Rhodes, A., Sasano, H., Schwartz, J.N., Sweep, F.C., Taube, S., Torlakovic, E.E., Valenstein, P., Viale, G., Visscher, D., Wheeler, T., Williams, R.B., Wittliff, J.L. and Wolff, A.C. (2010) American society of clinical oncology/college of American pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer. Arch. Pathol. Lab. Med., 134, 907-922. |
16 | Ahn, H.N., Jeong, S.Y., Bae, G.U., Chang, M., Zhang, D., Liu, X., Pei, Y., Chin, Y.W., Lee, J., Oh, S.R. and Song, Y.S. (2014) Selective estrogen receptor modulation by Larreanitida on MCF-7 cell proliferation and immature rat uterus. Biomol. Ther. (Seoul), 22, 347-354. DOI |
17 | Akahori, Y., Nakai, M., Yamasaki, K., Takatsuki, M., Shimohigashi, Y. and Ohtaki, M. (2008) Relationship between the results of in vitro receptor binding assay to human estrogen receptor alpha and in vivo uterotrophic assay: comparative study with 65 selected chemicals. Toxicol. In Vitro, 22, 225-231. DOI |
18 | Wuttke, W. and Seidlova-Wuttke, D. (2015) Black cohosh (Cimicifuga racemosa) is a non-estrogenic alternative to hormone replacement therapy. Clin. Phytoscience, 1, 12. DOI |
19 | Brown, A.M., Jeltsch, J.M., Roberts, M. and Chambon, P. (1984) Activation of pS2 gene transcription is a primary response to estrogen in the human breast cancer cell line MCF-7. Proc. Natl. Acad. Sci. U. S. A., 81, 6344-6348. DOI |
20 | Winuthayanon, W., Piyachaturawat, P., Suksamrarn, A., Ponglikitmongkol, M., Arao, Y., Hewitt, S.C. and Korach, K.S. (2009) Diarylheptanoid phytoestrogens isolated from the medicinal plant Curcuma comosa: biologic actions in vitro and in vivo indicate estrogen receptor-dependent mechanisms. Environ. Health Perspect., 117, 1155-1161. DOI |
21 | Zheng, X., Huang, H., Zheng, X. and Li, B. (2016) Olive oil exhibits osteoprotection in ovariectomized rats without estrogenic effects. Exp. Ther. Med., 11, 1881-1888. DOI |
22 | Soto, A.M., Sonnenschein, C., Chung, K.L., Fernandez, M.F., Olea, N. and Serrano, F.O. (1995) The E-SCREEN assay as a tool to identify estrogens: an update on estrogenic environmental pollutants. Environ. Health Perspect., 103 Suppl 7, 113-122. DOI |
23 | Park, M.K., Kwon, H.Y., Ahn, W.S., Bae, S., Rhyu, M.R. and Lee, Y. (2009) Estrogen activities and the cellular effects of natural progesterone from wild yam extract in mcf-7 human breast cancer cells. Am. J. Chin. Med., 37, 159-167. DOI |
24 | Zierau, O., Zheng, K.Y., Papke, A., Dong, T.T., Tsim, K.W. and Vollmer, G. (2014) Functions of danggui buxue tang, a chinese herbal decoction containing astragali radix and angelicae sinensis radix, in uterus and liver are both estrogen receptor- dependent and -independent. Evid. Based Complement. Alternat. Med., 2014, 438531. |
25 | Lomnitski, L., Padilla-Banks, E., Jefferson, W.N., Nyska, A., Grossman, S. and Newbold, R.R. (2003) A natural antioxidant mixture from spinach does not have estrogenic or antiestrogenic activity in immature CD-1 mice. J. Nutr., 133, 3584-3587. DOI |
26 | Han, S.H., Lee, T.H., Jang, J.Y., Song, H.K., Hong. S.K., Kim, Y.R. and Han, B.S. (2015) Mixture of extracts of Cynanchum wilfordii and Phlomis umbrosa Turcz. doesnot have an estrogenic effect in ovariectomized rats. Korean J. Food Sci. Technol., 47, 667-672. DOI |