Evaluation of Embryotoxic Potential of Olaquindox and Vitamin A in Micromass Culture and in Rats |
Kang, Hwan-Goo
(National Veterinary Research and Quarantine Service)
Ku, Hyun-Ok (National Veterinary Research and Quarantine Service) Jeong, Sang-Hee (GLP Research Center, College of Natural Sciences, Hoseo University) Cho, Joon-Hyoung (National Veterinary Research and Quarantine Service) Son, Seong-Wan (National Veterinary Research and Quarantine Service) |
1 | Paulsen, D.F. and Solursh, M. (1988). Microtiter micromass cultures of limb-bud mesenchymal cells. In Vitro Cell Dev. Biol., 24, 138-147. DOI |
2 | Aulthouse, A.L. and Hitt, D.C. (1994). The teratogenic effects of valproic acid in human chondrogenesis in vitro. Teratology, 49, 208-217. DOI ScienceOn |
3 | Belhadjali, H., Marguery, M.C., Journe, F., Giordano-Labadie, F., Lefebvre, H. and Bazex, J. (2002). Allergic and photoallergic contact dermatitis to Olaquindox in a pig breeder with prolonged photosensitivity. Photodermatol. Photoimmunol. Photomed., 18, 52-53. DOI ScienceOn |
4 | Beutin, L., Preller, E. and Kowalski, B. (1981). Mutagenicity ofquindoxin, its metabolites, and two substituted quinoxaline-di-N-oxides. Antimicrob. Agents. Chemother., 20, 336-343. DOI ScienceOn |
5 | Bronsch, K., Schneider, D. and Rigal-Antonelli, F. (1976).[Olaquindox - a new growth promoter in animal nutrition. 1.Effectiveness in raising piglets]. Z. Tierphysiol. Tierernahr. Futtermittelkd., 36, 211-221. |
6 | Commission of the European Communities, Commission Regulation 2788/98, Off. J. Eur. Communities L347 (31-32), 1998, 12- 23. |
7 | Chen, Q., Tang, S., Jin, X., Zou, J., Chen, K., Zhang, T. and Xiao, X. (2009). Investigation of the genotoxicity of quinocetone, carbadox and olaquindox in vitro using Vero cells. Food Chem. Toxicol.,47, 328-334. DOI ScienceOn |
8 | Ding, M.X., Wang, Y.L., Zhu, H.L. and Yuan, Z.H. (2006). Effects of cyadox and olaquindox on intestinal mucosal immunity and on fecal shedding of Escherichia coli in piglets. J. Anim. Sci., 84, 2367-2373. DOI ScienceOn |
9 | Flint, O.P. (1986). An in vitro test for teratogens: its practical application. Food Chem. Toxicol., 24, 627-631. DOI ScienceOn |
10 | Flint, O.P. (1993). In vitro tests for teratogens: desirable endpoints, test batteries and current status of the micromass teratogen test. Reprod. Toxicol., 7, 103-111. DOI ScienceOn |
11 | Flint, O.P. and Orton, T.C. (1984). An in vitro assay for teratogens with cultures of rat embryo midbrain and limb bud cells. Toxicol. Appl. Pharmacol., 76, 383-395. DOI ScienceOn |
12 | Schneider, D., Bronsch, K. and Richter, L. (1976). [Olaquindox--a new growth promoting feed additive. II. Effect on the performance in swine fattening]. Z. Tierphysiol. Tierernahr. Futtermittelkd., 36, 241-248. |
13 | Soprano, D.R., Tairis, N., Gyda, M., 3rd, Harnish, D.C., Jiang, H., Soprano, K.J. and Kochhar, D.M. (1993). Induction of RARbeta 2 gene expression in embryos and RAR-beta 2 transactivation by the synthetic retinoid Ro 13-6307 correlates with its high teratogenic potency. Toxicol. Appl. Pharmacol., 122, 159-163. DOI ScienceOn |
14 | Staples, R.E. and Schenell, V.L. (1964). Refinements in rapidclearing technique in the KOH-alizarin red S method for fetalbone. Stain. Technol., 39, 61-63. |
15 | Tzimas, G., Thiel, R., Chahoud, I. and Nau, H. (1997). The areaunder the concentration-time curve of all-trans-retinoic acid isthe most suitable pharmacokinetic correlate to the embryotoxicity of this retinoid in the rat. Toxicol. Appl. Pharmacol., 143, 436-444 DOI ScienceOn |
16 | WHO (1991). Joint FAO/WHO Expert Committee on Food Additives,WHO Food Additives Series 27, Olaquindox, ToxicologicalEvaluation of Certain Veterinary Drug Residues in Food(InChem;http://www.inchem.org). |
17 | Willhite, C.C., Jurek, A., Sharma, R.P. and Dawson, M.I. (1992). Structure-affinity relationships of retinoids with embryonic cellular retinoic acid-binding protein. Toxicol. Appl. Pharmacol.,112, 144-153. DOI ScienceOn |
18 | Wise, L.D., Clark, R.L., Rundell, J.O. and Robertson, R.T. (1990). Examination of a rodent limb bud micromass assay as a prescreen for developmental toxicity. Teratology, 41, 341-351. DOI ScienceOn |
19 | Zanetti, N.C. and Solursh, M. (1984). Induction of chondrogenesis in limb mesenchymal cultures by disruption of the actin cytoskeleton. J. Cell. Biol., 99, 115-123. DOI |
20 | Guntakatta, M., Matthews, E.J. and Rundell, J.O. (1984). Development of a mouse embryo limb bud cell culture system for the estimation of chemical teratogenic potential. Teratog. Carcinog. Mutagen., 4, 349-364. |
21 | Hao, L., Chen, Q. and Xiao, X. (2006). Molecular mechanism of mutagenesis induced by olaquindox using a shuttle vector pSP189/mammalian cell system. Mutat. Res., 599, 21-25. DOI ScienceOn |
22 | Kidney, J.K. and Faustman, E.M. (1995). Modulation of nitrosourea toxicity in rodent embryonic cells by O6-benzylguanine, a depletor of O6-methylguanine-DNA methyltransferase. Toxicol. Appl. Pharmacol., 133, 1-11. DOI ScienceOn |
23 | Kistler, A. (1987). Limb bud cell cultures for estimating the teratogenic potential of compounds. Validation of the test system with retinoids. Arch. Toxicol., 60, 403-414. DOI |
24 | Kistler, A. and Howard, W.B. (1990). Testing of retinoids for teratogenicity in vitro: use of micromass limb bud cell culture.Methods Enzymol., 190, 427-433. DOI |
25 | Lehmann, J.M., Jong, L., Fanjul, A., Cameron, J.F., Lu, X.P., Haefner, P., Dawson, M.I. and Pfahl, M. (1992). Retinoids selective for retinoid X receptor response pathways. Science,258, 1944-1946. DOI |
26 | Liu, Z.Y., Huang, L.L., Chen, D.M., Dai, M.H., Tao, Y.F. andYuan, Z.H. (2010). The metabolism and N-oxide reduction of olaquindox in liver preparations of rats, pigs and chicken. Toxicol Lett., 195, 51-59. DOI ScienceOn |
27 | Paulsen, D.F., Langille, R.M., Dress, V. and Solursh, M. (1988).Selective stimulation of in vitro limb-bud chondrogenesis by retinoic acid. Differentiation, 39, 123-130. DOI |