1 |
Krauskopf, A., Buetler, T.M., Nguyen, N.S., ,Macé, K. and Ruegg, U.T. (2002). Cyclosporin A-induced free radical generation is not mediated by cytochrome P-450. Br. J. Pharmacol., 135, 977-986.
DOI
ScienceOn
|
2 |
Taylor, A.L., Watson, C.J. and Bradley, J.A. (2005). Immunosuppressive agents in solid organ transplantation: mechanisms of action and therapeutic efficacy. Crit. Rev. Oncol. Hematol., 56,23-46.
DOI
ScienceOn
|
3 |
ten Brinke, A., Zwinderman, A.H., Sterk, P.J., Rabe, K.F. and Bel, E.H. (2004). "Refractory" eosinophilic airway inflammation in severe asthma: effect of parenteral corticosteroids. Am. J. Respir. Crit. Care Med., 170, 601-605.
DOI
ScienceOn
|
4 |
Yuce, A., Atessahin, A. and Ceribasi, A.O. (2008). Amelioration of cyclosporine A-induced renal, hepatic and cardiac damages by ellagic acid in rats. Basic Clin. Pharmacol. Toxicol., 103, 186-191.
DOI
ScienceOn
|
5 |
Young, B.A., Burdmann, E.A., Johnson, R.J., Alpers, C.E., Giachelli,. C. M., Eng, E., Andoh, T., Bennett, W.M. and Couser, W.G.(1995a). Cellular proliferation and macrophage influx precede interstitial fibrosis in cyclosporine nephrotoxicity. Kidney Int.,48, 439-448.
DOI
ScienceOn
|
6 |
Zhong, Z., Arteel, G.E., Connor, H.D., Yin, M., Frankenberg, M.V., Stachlewitz, R.F., Raleigh, J.A., Mason, R.P. and Thurman, R.G. (1998). Cyclosporin A increases hypoxia and free radical production in rat kidneys: prevention by dietary glycine. Am. J. Physiol., 275, F595-F604.
|
7 |
Tugwell, P., Pincus, T., Yocum, D., Stein, M., Gluck, O., Kraag,G., McKendry, R., Tesser, J., Baker, P. and Wells, G. (1995).Combination therapy with cyclosporine and methotrexate in severe rheumatoid arthritis. The methotrexate-cyclosporine combination study group. N Engl J Med., 333, 137-141.
DOI
ScienceOn
|
8 |
Watkins, P.B. (1990). The role of cytochromes P-450 in cyclosporine metabolism. J. Am. Acad. Dermatol., 23, 1301-1309.
DOI
ScienceOn
|
9 |
Weber, A.J., Soong, G., Bryan, R., Saba, S. and Prince, A. (2001).Activation of NF-kappaB in airway epithelial cells is dependent on CFTR trafficking and Cl- channel function. Am. J.Physiol. Lung Cell. Mol. Physiol., 281, L71-L78.
DOI
|
10 |
Young, B.A., Burdmann, E.A., Johnson, R.J., Andoh, T., Bennett,W.M., Couser, W.G. and Alpers, C.E. (1995b). Cyclosporine A induced arteriolopathy in a rat model of chronic cyclosporinenephropathy. Kidney Int., 48, 431-438.
DOI
ScienceOn
|
11 |
Boots, J.M., Christiaans, M.H. and van Hooff, J.P. (2004). Effect of immunosuppressive agents onlong-term survival of renal transplant recipients: focusonthe cardiovascular risk. Drugs., 64, 2047-2073.
DOI
ScienceOn
|
12 |
Capasso, G., Di Gennaro, C.I., Della Ragione, F., Manna, C., Ciarcia, R., Florio, S., Perna, A., Pollastro, R.M., Damiano, S., Mazzoni, O., Galletti, P. and Zappia, V. (2008). In vivo effect of the natural antioxidant hydroxytyrosol on cyclosporine nephrotoxicity in rats. Nephrol Dial Transplant., 23, 1186-1195.
|
13 |
Gokce, A., Oktar, S., Yonden, Z., Aydin, M., Ilhan, S., Ozkan, O.V., Davarci, M. and Yalcinkaya, F.R. (2009). Protective effect of caffeic acid phenethyl ester on cyclosporine A-induced nephrotoxicity in rats. Ren Fail., 31, 843-847.
DOI
ScienceOn
|
14 |
Jones, O.T.G. and Hancock, J.T. (2000). Free Radicals in Inflammation (P.G. Winyard, D.R. Blake, C.H. Evans, Eds.), Birkha, Switzerland, pp. 21-46.
|
15 |
Langford, C.A., Klippel, J.H., Balow, J.E., James, S.P. and Sneller,M.C. (1998a). Use of cytotoxic agents and cyclosporine in the treatment of autoimmune disease. Part 1: rheumatologic and renal diseases. Ann. Intern. Med., 128, 1021-1028.
DOI
ScienceOn
|
16 |
Rezzani, R. (2006). Exploring cyclosporine A-side effects and the protective role-played by antioxidants: the morphological and immunohistochemical studies. Histol Histopathol., 21, 301-16.
|
17 |
Rezzani, R., Rodella, L.F., Fraschini, F., Gasco, M.R., Demartini,G., Musicanti, C. and Reiter, R.J. (2009). Melatonin delivery in solid lipid nanoparticles: prevention of cyclosporine A induced cardiac damage. J. Pineal. Res., 46, 255-261.
DOI
ScienceOn
|
18 |
Shen, S.Y., Weir, M.R., Revie, D.R., Dagher, F.J., Bentley, F.R.and Chretien, P.B. (1987). Differentiation of acute rejection from acute cyclosporine nephrotoxicity in renal transplants peripheral T cell subset counts. Transplant Proc., 19, 1776-1779.
|
19 |
Romero, M., Garcia-Monzon, C., Clemente, G., Salcedo, M.,Alvarez, E., Majano, P.L. and Moreno-Otero, R. (2001). Intrahepatic expression of inducible nitric oxide synthase in acute liver allograft rejection: evidence of modulation by corticosteroids. Liver-Transplantation., 7, 16-21.
DOI
ScienceOn
|
20 |
Shaw, K.T., Ho, A.M., Raghavan, A., Kim, J., Jain, J., Park, J.,Sharma, S., Rao, A. and Hogan, P.G. (1995). Immunosuppressive drugs prevent a rapid dephosphorylation of transcription factor NFAT1 in stimulated immune cells. Proc. Natl. Acad.Sci. USA, 92, 11205-11209.
DOI
ScienceOn
|
21 |
Markell, M., Armenti, V., Danovitch, G. and Sumrani, N. (1994).Hyperlipidemia and glucose intolerance in the post-renal transplant patient. J. Am. Soc. Nephrol., 4, S37-S47.
|
22 |
Stallone, G., Infante, B., Schena, A., Di Paolo, S., Grandaliano, G.,Gesualdo, L. and Schena, F.P. (2004). Cardiovascular risk and renal transplantation. G. Ital.Nefrol., 21, 144-155.
|
23 |
Suthanthiran, M., Morris, R.E. and Strom, T.B. (1996). Immunosuppressants:cellular and molecular mechanisms of action. Am.J. Kidney Dis., 28, 159-172.
DOI
ScienceOn
|
24 |
Parra, T., de Arriba, G., Conejo, J.R., Cantero, M., Arribas, I.,Rodriguez-Puyol, D., Rodriguez-Puyol, M. and Carballo, F.,(1998b). Cyclosporine increases local glomerular synthesis ofreactive oxygen species in rats: effect of vitamin E on cyclosporine nephrotoxicity. Transplantation, 66, 1325-1329.
DOI
ScienceOn
|
25 |
Pascual, M., Theruvath, T., Kawai, T., Tolkoff-Rubin, N. andCosimi, A.B. (2002). Strategies to improve long-term outcomesafter renal transplantation. N Engl. J. Med., 346, 580-590.
DOI
ScienceOn
|
26 |
Racusen, L.C., Kone, B.C. and Solez, K. (1987). Early renal pathophysiology in an acute model of cyclosporine nephrotoxicityin rats. Ren Fail., 10, 29-37.
DOI
|
27 |
Perez de Lema, G., Arribas-Gomez, I., Ruiz-Gines, J.A., de Arriba,G., Prieto, A., Rodriguez-Puyol, D. and Rodriguez-Puyol, M.,(1997). Reactive oxygen species mediate the effects ofcyclosporine A on human cultured mesangial cells. Transplant.Proc., 29, 1241-1243.
DOI
ScienceOn
|
28 |
Perez de Lema, G., Arribas, I., Prieto, A., Parra, T., de Arriba,G., Rodríguez-Puyol, D. and Rodríguez-Puyol, M. (1998).Cyclosporin A-induced hydrogen peroxide synthesis by culturedhuman mesangial cells is blocked by exogenous antioxidants.Life Sci., 62, 1745-1753.
DOI
ScienceOn
|
29 |
Pickrell, M.D., Sawers, R. and Michael, J. (1988). Pregnancy after renal transplantation: severe intrauterine growth retardation during treatment with cyclosporin A. Br. Med. J., 19, 825.
|
30 |
Reis, F., Rocha-Pereira, P., Teixeira de Lemos, E., Parada, B., Baptista,S., Figueiredo, A., Santos-Silva, A., Costa-Almeida, C.,Mota, A. and Teixeira, F. (2007). Oxidative stress in cyclosporine-induced hypertension: evidence of beneficial effects or tolerance development with nitrate therapy. Transplant Proc., 39,2494-500.
DOI
ScienceOn
|
31 |
Rezzani, R. (2004). Cyclosporine A and adverse effects on organs:histochemical studies. Prog. Histochem. Cytochem., 39, 85-128.
DOI
ScienceOn
|
32 |
Moien-Afshari, F., McManus, B.M. and Laher, I. (2003). Immunosuppression and transplant vascular disease: benefits andadverse effects. Pharmacol. Ther., 100, 141-156.
DOI
ScienceOn
|
33 |
Mostafavi-Pour, Z., Zal, F., Monabati, A. and Vessal, M. (2008).Protective effects of a combination of quercetin and vitamin E against cyclosporine A-induced oxidative stress and hepatotoxicity in rats. Hepatol. Res., 38, 385-392.
DOI
ScienceOn
|
34 |
Olyaei, A.J., de Mattos, A.M. and Bennett, W.M. (2001). Nephrotoxicity of immunosuppressive drugs: new insight and preventive strategies. Curr. Opin. Crit. Care., 7, 384-389.
DOI
ScienceOn
|
35 |
Mourad, G., Vela, C., Ribstein, J. and Mimran, A. (1998). Longterm improvement in renal function after cyclosporine reduction in renal transplant recipients with histologically proven chronic cyclosporine nephropathy. Transplantation, 65, 661-667.
DOI
ScienceOn
|
36 |
Myers, B.D., Sibley, R., Newton, L., Tomlanovich, S.J., Boshkos,C., Stinson, E., Luetscher, J.A., Whitney, D.J., Krasny, D. andCoplon, N.S. (1988). The long-term course of cyclosporineassociated chronic nephropathy. Kidney Int., 33, 590-600.
DOI
ScienceOn
|
37 |
Nankivell, B.J., Borrows, R.J., Fung, C.L., O’Connell, P.J., Allen,R.D. and Chapman, J.R. (2003). The natural history of chronic allograft nephropathy. N Engl. J. Med., 349, 2326-2333.
DOI
ScienceOn
|
38 |
Pari, L. and Sivasankari, R. (2008). Effect of ellagic acid oncyclosporine A-induced oxidative damage in the liver of rats.Fundam Clin Pharmacol., 22, 395-401.
DOI
ScienceOn
|
39 |
Parra Cid, T., Conejo Garcia, J.R., Carballo Alvarez, F. and deArriba, G. (2003). Antioxidant nutrients protect against cyclosporine A nephrotoxicity. Toxicology, 189, 99-111.
DOI
ScienceOn
|
40 |
Parra, T., de Arriba, G., Arribas, I., Perez de Lema, G., Rodriguez-Puyol, D. and Rodriguez-Puyol, M. (1998a). Cyclosporine A nephrotoxicity: role of thromboxane and reactive oxygen species. J. Lab. Clin. Med., 131, 63-70.
DOI
ScienceOn
|
41 |
Langford, C.A., Klippel, J.H., Balow, J.E., James, S.P. and Sneller,M.C. (1998b). Use of cytotoxic agents and cyclosporine in the treatment of autoimmune disease. Part 2: inflammatory bowel disease, systemic vasculitis, and therapeutic toxicity. Ann.Intern. Med., 129, 49-58.
DOI
ScienceOn
|
42 |
Louie, B., Rajamahanty, S., Pyo, P., Choudhury, M. and Konno, S.(2010). Mode of cytotoxic action of nephrotoxic agents:oxidativestress and glutathione-dependent enzyme. BJU Int., 105,264-268.
DOI
ScienceOn
|
43 |
L’Azou, B., Medina, J., Frieauff, W., Cordier, A., Cambar, J. and Wolf, A. (1999). In vitro models to study mechanisms involved in cyclosporine A-mediated glomerular contraction. Arch. Toxicol.,73, 337-345.
DOI
|
44 |
Leong, A.C., Yong, J. and Salama, N. (2010). Lymphoproliferativedisorder of nasopharynx after long-standing cyclosporin therapy for psoriatic arthritis. J. Laryngol. Otol., 7, 1-3.
|
45 |
Lichtiger, S., Present, D.H., Kornbluth, A., Gelernt, I., Bauer, J.,Galler, G., Michelassi, F. and Hanauer, S. (1994). Cyclosporine in severe ulcerative colitis refractory to steroid therapy. N Engl.J. Med., 330, 1841-1845.
DOI
ScienceOn
|
46 |
Malyszko, J., Malyszko, J.S., Pawlak, K. and Mysliwiec, M.(1996). The coagulo-lytic system and endothelial function in cyclosporine-treated kidney allograft recipients. Transplantation,62, 828-830.
DOI
|
47 |
Marchetti, P. (2004). New-onset diabetes after transplantation. J.Heart Lung Transplant., 23, S194-S201.
DOI
ScienceOn
|
48 |
Mason, J. (1990). The pathophysiology of Sandimmune (cyclosporine) in man and animals. Pediatr. Nephrol., 4, 686-704.
DOI
|
49 |
McGrath, L.T., Treacy, R., McClean, E. and Brown, J.H. (1997).Oxidative stress in cyclosporin and azathioprine treated renaltransplant patients. Clin. Chim. Acta, 264, 1-12.
DOI
ScienceOn
|
50 |
Inselmann, G., Lawerenz, H.U., Nellessen, U. and Heidemann,H.T. (1994). Enhancement of cyclosporin A induced hepatoand nephrotoxicity by glutathione depletion. Eur. J. Clin. Invest., 24, 355-359.
DOI
ScienceOn
|
51 |
Josephine, A., Veena, C.K., Amudha, G., Preetha, S.P. and Varalakshmi, P. (2006). Evaluating the effect of sulphated polysaccharides on cyclosporine a induced oxidative renal injury. Mol. Cell. Biochem., 287, 101-108.
DOI
|
52 |
Ischiropoulos, H., Gow, A., Thom, S.R., Kooy, N.W., Royall, J.A.and Crow, J.P. (1999). Detection of reactive nitrogen speciesusing 2,7-dichlorodihydrofluorescein and dihydrorhodamine123. In Methods in Enzymology: Oxygen Radicals in BiologicalSystem (Packer, L., ed.) Academic Press, (Part D) (Vol. 301)pp. 367-373.
|
53 |
Josephine, A., Amudha, G., Veena, C.K., Preetha, S.P. and Varalakshmi, P. (2007). Oxidative and nitrosative stress mediated renal cellular damage induced by cyclosporine A: role of sulphated polysaccharides. Biol. Pharm. Bull., 30, 1254-1259.
DOI
ScienceOn
|
54 |
Josephine, A., Nithya, K., Amudha, G., Veena, C.K., Preetha, S.P.and Varalakshmi, P. (2008). Role of sulphated polysaccharides from sargassum wightii in cyclosporine A-induced oxidative liver injury in rats. BMC Pharmacol., 8, 4.
|
55 |
Jung, J.Y., Kang, G.C., Jeong, Y.J., Kim, S.H., Kwak, Y.G. andKim, W.J. (2009). Proteomic analysis in cyclosporin A-inducedovergrowth of human gingival fibroblasts. Biol. Pharm. Bull.,32, 1480-1485.
DOI
ScienceOn
|
56 |
Kobashigawa, J.A. and Kasiske, B.L. (1997). Hyperlipidemia insolid organ transplantation. Transplantation, 63, 331-338.
DOI
ScienceOn
|
57 |
Kumar, M.S., Xiao, S.G., Fyfe, B., Sierka, D., Heifets, M., Moritz,M.J., Saeed, M.I. and Kumar, A. (2005). Steroid avoidance in renal transplantation using basiliximab induction,cyclosporinebased immunosuppression and protocol biopsies. Clin Transplant., 19, 61-69.
DOI
ScienceOn
|
58 |
Fraser, A., Veale, D.J. and Emery, P. (2003). Cyclosporin treatment in psoriatic arthritis: a cause of severe leg pain. Ann. Rheum. Dis., 62, 489.
DOI
ScienceOn
|
59 |
Halliwell, B. and Gutteridge, J.M.C. (1999). Free Radicals in Biology and Medicine, Oxford University Press.
|
60 |
Fridovich, I. (1978). The biology of oxygen radicals. Science, 201,875-880.
DOI
|
61 |
Hancock, J.T., Desikan, R. and Neill, S.J. (2001). Role of reactive oxygen species in cell signalling pathways. Biochemical Society Transactions, pp. 345-350.
|
62 |
Herrero, J.I., Quiroga, J., Sangro, B., Beloqui, O., Pardo, F., Cienfuegos, J.A. and Prieto, J. (2000). Hyperhomocysteinemia inliver transplant recipients: prevalence and multivariate analysis of predisposing factors. Liver Transplant., 6, 614-618.
DOI
ScienceOn
|
63 |
Heydendael, V.M., Spuls, P.I., Opmeer, B.C., de Borgie, C.A., Reitsma, J.B., Goldschmidt, W.F., Bossuyt, P.M., Bos, J.D. and de Rie, M.A. (2003). Methotrexate versus cyclosporine in moderate-to-severe chronic plaque psoriasis. N Engl. J. Med., 349,658-665.
DOI
ScienceOn
|
64 |
Hjelmesaeth, J., Asberg, A., Muller, F., Hartmann, A. and Jenssen,T. (2005). New-onset posttransplantation diabetes mellitus:insulin resistance or insulinopenia? Impact of immunosuppressive drugs, cytomegalovirus and hepatitis C virus infection. Curr. Diabetes Rev., 1, 1-10.
DOI
|
65 |
Ho, S., Clipstone, N., Timmermann, L., Northrop, J., Graef, I., Fiorentino, D., Nourse, J. and Crabtree, G.R. (1996). The mechanism of action of cyclosporin A and FK506. Clin. Immunol.Immunopathol., 80, S40-S45.
DOI
ScienceOn
|
66 |
Inselmann, G., Barth, A., Engemann, R. and Heidemann, H.T.(1991). Cyclosporin-A induced lipid peroxidation in humanliver microsomes and its influence on cytochrome P-450. Eur.J. Clin. Invest., 21, 461-465.
DOI
ScienceOn
|
67 |
de Arriba, G., de Hornedo, J.P., Rubio, S.R., Fernandez, M.C.,Martínez, S.B., Camarero, M.M. and Cid, T.P. (2009). Vitamin E protects against the mitochondrial damage caused by cyclosporin A in LLC-PK1 cells. Toxicol. Appl. Pharmacol.,239, 241-250.
DOI
ScienceOn
|
68 |
Diao, T.J., Yuan, T.Y. and Li, Y.L. (2002). Immunologic role of nitric oxide in acute rejection of golden hamster to rat liver xenotransplantation. World J. Gastroenterol., 8, 746-751.
DOI
|
69 |
Deby, C. and Goutier, R. (1990). New perspectives on the biochemistry of superoxide anion and the efficiency of superoxide dismutases. Biochem.Pharmacol., 39, 399-405.
DOI
ScienceOn
|
70 |
de Mattos, A.M., Olyaei, A.J. and Bennett, W.M. (2000). Nephrotoxicity of immunosuppressive drugs: long-term consequences and challenges for the future. Am. J. Kidney Dis., 35, 333-346
DOI
ScienceOn
|
71 |
Doyle, V., Virji, S. and Crompton, M. (1999). Evidence that cyclophilin-A protects cells against oxidative stress. Biochem. J. 341,127-132.
DOI
|
72 |
Hong, F., Lee, J., Song, J.W., Lee, S.J., Ahn, H., Cho, J.J., Ha, J.and Kim, S.S. (2002). Cyclosporin A blocks muscle differentiation by inducing oxidative stress and inhibiting the peptidylprolyl-cis–trans isomerase activity of cyclophilin A: cyclophilin A protects myoblasts from cyclosporin A-induced cytotoxicity.FASEB J., 16, 1633-1635.
DOI
|
73 |
Durak, I., Karabacak, H.I., Buyukkocak, S., Cimen, M.Y., Kacmaz,M., Omeroglu, E. and Ozturk, H.S. (1998). Impaired antioxidant defense system in the kidney tissues from rabbits treated with cyclosporine. Protective effects of vitamins E and C. Nephron, 78, 207-211.
|
74 |
Ebru, U., Burak, U., Yusuf, S., Reyhan, B., Arif, K., Faruk, T.H.,Emin, M., Aydin, K., Atilla, I.I., Semsettin, S.nand Kemal, E.(2008). Cardioprotective effects of Nigella sativa oil on cyclosporine A-induced cardiotoxicity in rats. Basic Clin Pharmacol. Toxicol., 103, 574-580.
DOI
ScienceOn
|
75 |
Erlanger, B.F. (1992). Do we know the site of action of cyclosporin? Immunol. Today, 13, 487-490.
DOI
ScienceOn
|
76 |
Baid, S., Cosimi, A.B., Farrell, M.L., Schoenfeld, D.A., Feng, S.,Chung, R.T., Tolkoff-Rubin, N. and Pascual, M. (2001). Posttransplant diabetes mellitus in liver transplant recipients: risk factors, temporal relationship with hepatitis C virus allografthepatitis, and impact on mortality. Transplantation, 72, 1066-1072.
DOI
ScienceOn
|
77 |
Al-Malki, A.L. and Moselhy, S.S. (2010). The protective effect of epicatchin against oxidative stress and nephrotoxicity in rats induced by cyclosporine. Hum. Exp. Toxicol., [Epub ahead of print].
|
78 |
Amudha, G., Josephine, A., Sudhahar, V. and Varalakshmi, P.(2007). Protective effect of lipoic acid on oxidative and peroxidative damage in cyclosporine A-induced renal toxicity. Int.Immunopharmacol., 7, 1442-1449.
DOI
ScienceOn
|
79 |
Arnadottir, M., Hultberg, B., Vladov, V., Nilsson-Ehle, P. and Thysell, H. (1996). Hyperhomocysteinemia in cyclosporine-treatedrenal transplant recipients, Transplantation, 61, 509-512.
DOI
|
80 |
Beckman, J.A., Creager, M.A. and Libby, P. (2002). Diabetes andatherosclerosis: epidemiology, pathophysiology, and management.JAMA, 287, 2570-2581.
DOI
ScienceOn
|
81 |
Behforouz, N.C. and Wenger, C.D. (1988). Immunomodulation of murine leishmaniasis with cyclosporin A. Adv. Exp. Med. Biol., 239, 379-384.
DOI
|
82 |
Bilchick, K.C., Henrikson, C.A., Skojec, D., Kasper, E.K. andBlumenthal, R.S. (2004). Treatment of hyperlipidemia in cardiactransplant recipients. Am. Heart J., 148, 200-210.
DOI
ScienceOn
|
83 |
Calne, R.Y., White, D.J., Thiru, S., Evans, D.B., McMaster, P.,Dunn, D.C., Craddock, G.N., Pentlow, B.D. Rolles, K. (1978).Cyclosporin A in patients receiving renal allografts fromcadaver donors. Lancet, 2, 1323-1327.
|
84 |
Chen, C., Jeon, H., Johnston, T.D., Gedaly, R., McHugh, P.P. andRanjan, D. (2008). Cyclosporin A-induced lipid and proteinoxidation in human B-cells and in Epstein-Barr virus-infectedB-cells is prevented by antioxidants. J. Invest. Surg., 21, 201-208.
DOI
ScienceOn
|