In Vitro Studies on the Genotoxic Effects of Wood Smoke Flavors |
Chung, Young-Shin
(Medvill Co., Ltd)
Ahn, Jun-Ho (Department of Biology, College of Natural Sciences, University of Incheon) Eum, Ki-Hwan (Department of Biology, College of Natural Sciences, University of Incheon) Choi, Seon-A (Medvill Co., Ltd) Oh, Se-Wook (Korea Food Research Institute) Kim, Yun-Ji (Korea Food Research Institute) Park, Sue-Nie (Division of Genetic Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) Yum, Young-Na (Division of Genetic Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) Kim, Joo-Hwan (Division of Genetic Toxicology, National Institute of Toxicological Research, Korea Food and Drug Administration) Lee, Michael (Department of Biology, College of Natural Sciences, University of Incheon) |
1 | Dean, B.J. and Danford, N. (1984). Assays for the detection of chemically-induced chromosome damage in cultured mammalian cells in Mutagenicity testing - a practical approach (S. Venitt and J.M. Parry, Eds.). IRL Press Limited, Oxford. UK, pp. 187-232 |
2 | Kim, J.-Y., Koh, W.S. and Lee, M. (2006). Validation of photocomet assay as a model for the prediction of photocarcinogenicity. Toxicol. Res., 22, 423-429 과학기술학회마을 |
3 | McCann, J., Horn, L. and Kaldoer, J. (1984). An evaluation of Salmonella (Ames) test data in the published literature: application of statistical procedures and analysis of mutagenicity potency. Mutat. Res., 134, 1-47 DOI ScienceOn |
4 | Singh, N.P., McCoy, M.T., Tice, R.R. and Schneider, E.L. (1988). A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res., 175, 184- 191 DOI ScienceOn |
5 | Lorge, E., Thybaud, V., Aardema, M.J., Oliver, J., Wakata, A., Lorenzon, G. and Marzin, D. (2006). SFTG international collaborative study on in vitro micronucleus test I. General conditions and overall conclusions of the study. Mutat. Res., 607, 13-36 DOI ScienceOn |
6 | Fenech, M. (2000). The in vitro micronucleus technique. Mutat. Res., 455, 81-95 DOI ScienceOn |
7 | Hong, M.-Y., Kim, J.-Y., Lee, Y.-M. and Lee, M. (2005). Assessment of sensitivity of photo-chromosomal assay in the prediction of photo-carcinogenicity. Toxicol. Res., 21, 99-105 |
8 | Kirsch-Volders, M., Sofuni, T., Aardema, M., Albertini, S., Eastmond, D., Fenech, M., Ishidate Jr, M., Kirchner, S., Lorge, E., Morita, T., Norppa, H., Surrallés, J., Vanhauwaert, A. and Wakata, A. (2003). Report from the in vitro micronucleus assay working group. Mutat. Res., 540, 153-163 DOI ScienceOn |
9 | Braun, A.G., Busby, W.F.J., Jackman, J., Halpin, P.A. and Thilly, W.G. (1987). Commercial hickory-smoke flavouring is a human lymphoblast mutagen but does not induce lung adenomas in newborn mice. Food Chem. Toxicol., 25, 331-335 DOI ScienceOn |
10 | Fenech, M. and Morley, A.A. (1985). Measurement of micronuclei in lymphocytes. Mutat. Res., 147, 29-36 DOI ScienceOn |
11 | Oliver, J., Meunier, J.R., Awogi, T., Elhajouji, A., Ouldelhkim, M.C., Bichet, N., Thybaud, V., Lorenzon, G., Marzin, D. and Lorge, E. (2006). SFTG international collaborative study on in vitro micronucleus test V. Using L5178Y cells. Mutat. Res., 607, 125-152 DOI ScienceOn |
12 | Simon, R., de la Calle, B., Palme, S., Meier, D. and Anklam, E. (2005). Composition and analysis of luquid smoke flavouring primary products. J. Sep. Sci., 28, 871-882 DOI ScienceOn |
13 | European Commission (2003). Regulation (EC) No 2065/2003 of the European Parliament and of the Council of 10 November 2003 on smoke flavourings used or intended for use in or on foods. Off. J. Eur. Comm., L 309, 1-8 |
14 | Muller, L. and Sofuni, T. (2000). Appropriate levels of cytotoxicity for genotoxicity tests using mammalian cells in vitro. Environ. Mol. Mutagen., 35, 202-205 DOI ScienceOn |
15 | Burlinson, B., Tice, R.R., Speit, G., Agurell, E., Brendler-Schwaab, S.Y., Collins, A.R., Escobar, P., Honma, M., Kumaravel, T.S., Nakajima, M., Sasaki, Y.F., Thybaud, V., Uno, Y., Vasquez, M. and Hartmann, A. (2007). Fourth International Workgroup on Genotoxicity testing: results of the in vivo Comet assay workgroup. Mutat. Res., 627, 31-35 DOI ScienceOn |
16 | Galloway, S.M. (2000). Cytotoxicity and chromosome aberrations in vitro: Experience in industry and the case for an upper limit on toxicity in the aberration assay. Environ. Mol. Mutagen., 35, 191-201 DOI ScienceOn |
17 | Pszczola, D.E. (1995). Tour highlights production and uses of smoke-based flavors. Food Technol., 49, 70-74 |
18 | OECD (1997). OECD Guidelines for the Testing of Chemicals (July 21, 1997) TG No. 471 'Bacterial Reverse Mutation Test' |
19 | Giannotti, E., Vandin, L., Repeto, P. and Comelli, R. (2002). A comparison of the in vitro comet assay with the in vitro chromosome aberration assay using whole blood or Chinese hamster lung cells: validation study using a range of novel pharmaceuticals. Mutagenesis, 17, 163-170 DOI ScienceOn |
20 | Brooks, P. (1977). Mutagenicity of polycyclic aromatic hydrocarbons. Mutat. Res., 39, 257-284 DOI ScienceOn |
21 | Richardson, C., Williams, D.A., Allen, J.A., Amphlett, G., Chanter, D.O. and Phillips, B. (1989). Analysis of data from in vitro cytogenetics assays in Statistical evaluation of mutagenicity test data (D.J. Kirkland, Ed.). Cambridge University Press, Cambridge, U.K. pp. 141-154 |
22 | Tice, R.R., Agurell, E., Anderson, D., Burlinson, B., Hartmann, A., Kobayashi, H., Miyamae, Y., Rojas, E., Ryu, J.C. and Sasaki, Y.F. (2000). Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing. Environ. Mol. Mutagen., 35, 206-221 DOI ScienceOn |
23 | Hartmann, A., Agurell, E., Beevers, C., Brendler-Schwaab, S., Burlinson, B., Clay, P., Collins, A., Smith, A., Speit, G., Thybaud, V. and Tice, R.R. (2003). Recommendations for conducting the in vivo alkaline Comet assay. 4th International Comet Assay Workshop. Mutagenesis, 18, 45-51 DOI ScienceOn |
24 | Chung, Y.-S., Lee, S-J., Choi, S.-A., Lee, J.-H., Ryu, J.-C. and Hong, E.-K. (2004). Genotoxicity study of water extract of Anemarrhena asphodeloid and Phellodendron amurense in bacterial and mammalian cell systems. Toxicol. Res., 20, 43-47 |
25 | Pool, B.L., Renner, H.W. and Baltes, W. (1983). Genotoxicity of brown-colored polymerization products formed in smoke flavors. Nutr. Cancer, 5, 26-33 DOI |
26 | Putnam, K.P., Bombick, D.W., Avalos, J.T. and Doolittle, D.J. (1999). Comparison of the cytotoxic and mutagenic potential of liquid smoke food flavourings, cigarette smoke condensate and wood smoke condensate. Food Chem. Toxicol., 37, 1113-1118 DOI ScienceOn |
27 | Rojas, E., Lopez, M.C. and Valverde, M. (1999). Single cell gel electrophoresis assay: methodology and applications. J. Chromatogr. B Biomed. Sci. Appl., 722, 225-254 DOI ScienceOn |
28 | Maron, D.M. and Ames, B.N. (1983). Revised methods for the Salmonella mutagenicity test. Mutat. Res., 113, 173-215 DOI |
29 | Asita, A.O., Matsui, M., Nohmi, T., Matsuoka, A., Hayashi, M., Ishidate, M.J., Sofuni, T., Koyano, M. and Matsushita, H. (1991). Mutagenicity of wood smoke condensates in the Salmonella/microsome assay. Mutat. Res., 264, 7-14 DOI ScienceOn |
30 | Corvi, R., Albertini, S., Hartung, T., Hoffmann, S., Maurici, D., Pfuhler, S., van Benthem, J. and Vanparys, P. (2008). ECVAM retrospective validation of in vitro micronucleus test (MNT). Mutagenesis, 23, 271-283 DOI ScienceOn |
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