Clinical and Toxico-pathological Parameters for Deoxynivalenol Intoxication in B6C3F1 Mice
![]() |
Kim, Eun-Joo
(Toxicological Lab, Toxicological & Chemistry Division, National Veterinary Research & Quarantine Service)
Jeong, Sang-Hee (Toxicological Lab, Toxicological & Chemistry Division, National Veterinary Research & Quarantine Service) Ku, Hyun-Ok (Toxicological Lab, Toxicological & Chemistry Division, National Veterinary Research & Quarantine Service) Kang, Hwan-Goo (Toxicological Lab, Toxicological & Chemistry Division, National Veterinary Research & Quarantine Service) Cho, Joon-Hyoung (Toxicological Lab, Toxicological & Chemistry Division, National Veterinary Research & Quarantine Service) |
1 | Osweiler, G.D., Carr, T.F., Sanderson, T.P., Carson, T.L. and Kinker, J.A. (1995). Water deprivation-sodium ion toxicosis in cattle. J. Vet. Diagn. Invest., 7, 583-585 DOI ScienceOn |
2 | Betina, V. (1989). Structure-activity relationships among mycotoxins. Chem. Biol. Interact., 71, 105-146 DOI ScienceOn |
3 | Forsyth, D.M., Yoshizawa, T., Morooka, N. and Tuite, J. (1977). Emetic and refusal activity of deoxynivalenol to swine. Appl. Envir. Microbiol., 34, 547 |
4 | Kubena, L.F., Huff, W.E., Harvey, R.B., Corrier, D.E., Philips, T.D. and Rottinghause, G.E. (1989). Individual and combined toxicity of deoxynivalenol and T-2 toxin in broiler chicks. Poult. Sci., 68, 622-626 DOI |
5 | Thomson, W.L. and Wannemacher, R.W. Jr. (1986). Structurefunction relationships of 12,13-epoxytrichothecene mycotoxins in cell culture: comparison to whole animal lethality. Toxicon., 24, 985-994 DOI ScienceOn |
6 | WHO (2001). Biomarkers in risk assessment: Validity and Validation. Environ. Health, Crit. No. 222 |
7 | Forsell, J.H., Witt, M.F., Tai, J.H., Jensen, R. and Pestka, J.J. (1986). Effects of 8-week exposure of the B6C3F1 mouse to dietary deoxynivalenol (vomitoxin) and zearalenone. Fd. Chem. Toxic., 24, 213-219 DOI ScienceOn |
8 | Pestka, J.J. and Smolinski, A.T. (2005). Deoxynivalenol: toxicology and potential effects on humans. J. Toxicol. Environ. Health, 8, 39-69 DOI ScienceOn |
9 | WHO (1990). Selected mycotoxins: Ochratoxin, tricothecenes, ergot. Environ. Health, Crit. No. 105 |
10 | Kinser, S., Jia, Q., Li, M., Laughter, A., Cornwell, P.D., Christopher Corton, J. and Pestka, J.J. (2004). Gene expression profiling in spleens of deoxynivalenol-exposed mice: immediate early genes as primary targets. J. Toxicol. Environ. Health, 67, 1423-1441 DOI ScienceOn |
11 | Rotter, B.A. (1996). Toxicology of deoxynivalenol (vomitoxin). J. Toxicol. Environ. Health, 48, 1-34 |
12 | Goyarts, T., Grove, N. and Dänicke, S. (2006). Effect of the Fusarium toxin deoxynivalenol wheat given subchronically or as one single dose on the in vivo protein synthesis of peripheral blood lymphocytes and plasma protein in the pig. Fd. Chem. Toxicol., 44, 1953-1965 DOI ScienceOn |
13 | Meky, F.A., Turner, P.C., Ashcroft, A.E., Miller, J.D, Qiao, Y.L., Roth, M.J. and Wild, C.P. (2003). Development of a urinary biomarker of human exposure to deoxynivalenol. Fd. Chem. Toxicol., 41, 265-273 DOI ScienceOn |
14 | Creppy, E.E. (2002). Update of survey, regulation and toxic effects of mycotoxins in Europe. Toxicol. Lett., 127, 19-28 DOI ScienceOn |
15 | Osweiler, G.D. (2000). Mycotoxins. Contemporary issue of food anomal health and productivity. Vet. Clin. North Am. Fd. Anim. Pract., 16, 511-530 DOI |
16 | MHLW (Minisrty of Health, Labour and Welfare) (2006). The Nineteenth seminar for visiting food hygiene experts |
![]() |