1 |
Akhurst, R.J. and Balmain, A. (1999). Genetic events and the role of TGF- in epithelial tumor progression. J. Pathol., 187, 82-90
DOI
ScienceOn
|
2 |
Atfi, A., Djelloul, S., Chastre, E., Davis, R. and Gespach, C. (1997). Evidence for a role of Rho-like GTPases and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) in transforming growth factor -mediated signaling. J. Biol. Chem., 272, 1429-1432
DOI
ScienceOn
|
3 |
Attisano, L. and Wrana, J.L. (2002). Signal transduction by the TGF- superfamily. Science, 296, 1646-1647
DOI
ScienceOn
|
4 |
Bakin, A.V., Tomlinson, A.K., Bhowmick, N.A., Moses, H.L. and Arteaga, C.L. (2000). Phosphatidylinositol 3-kinase function is required for transforming growth factor -mediated epithelial to mesenchymal transition and cell migration. J. Biol. Chem., 275, 36803-36810
DOI
ScienceOn
|
5 |
Dumont, N., Bakin, A.V. and Arteaga, C.L. (2003). Autocrine transforming growth factor- signaling mediates Smadindependent motility in human cancer cells. J. Biol. Chem., 278, 3275-3285
DOI
ScienceOn
|
6 |
Festuccia, C., Bologna, M., Gravina, G.L., Guerra, F., Angelucci, A., Villanova, I., Millimaggi, D. and Teti, A. (1999). Osteoblast conditioned media contain TGF1 and modulate the migration of prostate tumor cells and their interactions with extracellular matrix components. Int. J. Cancer., 81, 395-403
DOI
ScienceOn
|
7 |
Itoh, S., Itoh, F., Goumans, M.J. and ten Dijke, P. (2000). Signaling of transforming growth factor- family members through Smad proteins. Eur. J. Biochem., 267, 6954-6967
DOI
ScienceOn
|
8 |
Karsdal, M.A., Fjording, M.S., Foged, N.T., Delaisse, J.M. and Lochter, A. (2001). Transforming growth factor--induced osteoblast elongation regulates osteoclastic bone resorption through a p38 mitogen-activated protein kinase- and matrix metalloproteinase dependent pathway. J. Biol. Chem., 276, 39350-39358
DOI
ScienceOn
|
9 |
Kim, M.S., Lee, E.J., Kim, H.R. and Moon, A. (2003). p38 Kinase is a key signaling molecule for H-Ras-induced cell motility and invasive phenotype in human breast epithelial cells. Cancer Res., 63, 5454-5461
|
10 |
Lochter, A., Galosy, S., Muschler, J., Freedman, N., Werb, Z. and Bissell, M.J. (1997). Matrix metalloproteinase stromelysin- 1 triggers a cascade of molecular alterations that leads to stable epithelial-tomesenchymal conversion and a premalignant phenotype in mammary epithelial cells. J. Cell Biol., 139, 1861-1872
DOI
ScienceOn
|
11 |
Piek, E., Moustakas, A., Kurisaki, A., Heldin, C.H. and ten Dijke, P. (1999). TGF- type I receptor/ALK-5 and Smad proteins mediate epithelial to mesenchymal transdifferentiation in NMuMG breast epithelial cells. J. Cell Sci., 112, 4557-4568
|
12 |
Reiss, M. and Barcellos-Hoff, M.H. (1997). Transforming growth factor in breast cancer: a working hypothesis. Breast Cancer Res. Treat., 45, 81-95
DOI
ScienceOn
|
13 |
Taipale, J., Saharinen, J. and Keski-Oja, J. (1998). Extracellular matrix-associated transforming growth factor-: role in cancer cell growth and invasion. Adv. Cancer Res., 75, 87-134
DOI
|
14 |
Tryggvason, K., Hoyhtya, M. and Pyke, C. (1993). Type IV collagenases in invasive tumors. Breast Cancer Res. Treat.,24, 209-218
DOI
|
15 |
Tanaka, Y., Nakayamada, S., Fujimoto, H., Okada, Y., Umehara, H. and Kataoka, T. (2002). H-Ras/mitogen-activated protein kinase pathway inhibits integrin-mediated adhesion and induces apoptosis in osteoblasts. J. Biol. Chem., 277, 21446-21452
DOI
ScienceOn
|
16 |
Ten Dijke, P. and Hill, C.S. (2004). New insights into TGF-- Smad signalling. Trends Biochem. Sci., 29, 265-273
DOI
ScienceOn
|
17 |
Tobin, S.W., Douville, K., Benbow, U., Brinckerhoff, C.E., Memoli, V.A. and Arrick, B.A. (2002). Consequences of altered TGF- expression and responsiveness in breast cancer: Evidence for autocrine and paracrine effects. Oncogene, 21, 108-118
DOI
ScienceOn
|
18 |
Ura, H., Bonfil, R.D., Reich, R., Reddel, R., Pfeifer, A., Harris, C.C. and Klein-Szanto, A.J. (1989). Expression of type IV collagenase and procollagen genes and its correlation with the tumorigenic, invasive, and metastatic abilities of oncogene-transformed human bronchial epithelial cells. Cancer Res., 49, 4615-4621
|
19 |
Valcourt, U., Kowanetz, M., Niimi, H., Heldin, C.H. and Moustakas, A. (2005). TGF- and the Smad signaling pathway support transcriptomic reprogramming during epithelialmesenchymal cell transition. Mol. Biol. Cell., 16, 1987- 2002
DOI
ScienceOn
|
20 |
Whitman, M. (1998). Smads and early developmental signaling by the TGF superfamily. Genes Dev., 12, 2445-2462
DOI
ScienceOn
|
21 |
Kim, E.S., Kim, M.S. and Moon, A. (2005). Transforming growth factor (TGF)- in conjunction with H-ras activation promotes malignant progression of MCF10A breast epithelial cells. Cytokine, 29, 84-91
DOI
ScienceOn
|
22 |
Cui, W., Fowlis, D.J., Bryson, S., Duffie, E., Ireland, H., Balmain, A. and Akhurst, R.J. (1996). TGF inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice. Cell, 86, 531-542
DOI
ScienceOn
|
23 |
De Larco, J.E. and Todaro, G.J. (1978). Growth factors from murine sarcoma virus-transformed cells. Proc. Natl. Acad. Sci. U.S.A., 75, 4001-4005
|
24 |
Hanafusa, H., Ninomiya-Tsuji, J., Masuyama, N., Nishita, M., Fujisawa, J. and Shibuya, H. (1999). Involvement of the p38 mitogenactivated protein kinase pathway in transforming growth factor -induced gene expression. J. Biol. Chem., 274, 27161-27167
DOI
|
25 |
Hartsough, M.T. and Mulder, K.M. (1995). Transforming growth factor activation of p44mapk in proliferating cultures of epithelial cells. J. Biol. Chem., 270, 7117-7124
DOI
ScienceOn
|
26 |
Rosivatz, E., Becker, I., Specht, K., Fricke, E., Luber, B., Busch, R., Hofler, H. and Becker, K.F. (2002). Differential expression of the epithelial-mesenchymal transition regulators anail, SIP1, and twist in gastric cancer. Am. J. Pathol., 161, 1881-1891
DOI
ScienceOn
|
27 |
Tian, F., Byfield, S.D., Parks, W.T., Stuelten, C.H., Nemani, D., Zhang, Y.E. and Roberts, A.B. (2004). Smad-binding defective mutant of transforming growth factor type I receptor enhances tumorigenesis but suppresses metastasis of breast cancer cell lines. Cancer Res., 64, 4523- 4530
DOI
ScienceOn
|
28 |
Massague, J. (1998). TGF- signal transduction. Annu. Rev. Biochem., 67, 753-791
DOI
ScienceOn
|
29 |
Yanagisawa, K., Osada, H., Masuda, A., Kondo, M., Saito, T., Yatabe, Y., Takagi, K. and Takahashi, T. (1998). Induction of apoptosis by Smad3 and down-regulation of Smad3 expression in response to TGF- in human normal lung epithelial cells. Oncogene, 17, 1743-1747
DOI
|
30 |
Akhurst, R.J. and Derynck, R. (2001). TGF- signaling in cancer- a double-edged sword. Trends Cell Biol., 11, S44- S51
|
31 |
Miettinen, P.J., Ebner, R., Lopez, A.R. and Derynck, R. (1994). TGF- induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors. J. Cell Biol., 127, 2021-2036
DOI
|
32 |
Sano, Y., Harada, J., Tashiro, S., Gotoh-Mandeville, R., Maekawa, T. and Ishii, S. (1999). ATF2 is a common nuclear target of Smad and TAK1 pathways in transforming growth factor- signaling. J. Biol. Chem., 274, 8949- 8957
DOI
ScienceOn
|
33 |
Stetler-Stevenson, W.G. (1990). Type IV collagenases in tumor invasion and metastasis. Cancer Metastasis Rev., 9, 289- 303
DOI
|
34 |
Watson, D.M., Elton, R.A., Jack, W.J., Dixon, J.M., Chetty, U. and Miller, W.R. (1991). The H-ras oncogene product p21 and prognosis in human breast cancer. Breast Cancer Res. Treat., 17, 161-169
DOI
|
35 |
Wahl, S.M., Allen, J.B., Weeks, B.S., Wong, H.L. and Klotman, P.E. (1993). Transforming growth factor enhances integrin expression and type IV collagenase secretion in human monocytes. Proc. Natl. Acad. Sci. U.S.A., 90, 4577-4581
|
36 |
Zhang, Y. and Derynck, R. (1999). Regulation of Smad signalling by protein associations and signalling crosstalk. Trends Cell. Biol., 9, 274-279
DOI
ScienceOn
|
37 |
Bierie, B. and Moses, H.L. (2006). TGF- and cancer. Cytokine Growth Factor Rev., 17, 29-40
DOI
ScienceOn
|
38 |
Song, H., Ki, S.H., Kim, S.G. and Moon, A. (2006). Activating transcription factor (ATF)2 mediates MMP-2 transcriptional activation induced by p38 MAPK in breast epithelial cells. Cancer Res., 66, 10487-10496
DOI
ScienceOn
|
39 |
Clark, G.J. and Der, C.J. (1995). Aberrant function of the Ras signal transduction pathway in human breast cancer. Breast Cancer Res. Treat., 35, 133-144
DOI
|
40 |
McEarchern, J.A., Kobie, J.J., Mack, V., Wu, R.S., Meade-Tollin, L. and Arteaga, C.L. (2001). Invasion and metastasis of a mammary tumor involves TGF- signaling. Int. J. Cancer., 91, 76-82
DOI
ScienceOn
|
41 |
Bakin, A.V., Rinehart, C., Tomlinson, A.K. and Arteaga, C.L. (2002). p38 mitogen-activated protein kinase is required for TGF-mediated fibroblastic transdifferentiation and cell migration. J. Cell. Sci., 115, 3193-3206
|
42 |
Manning, G., Whyte, D.B., Martinez, R., Hunter, T. and Sudarsanam, S. (2002). The protein kinase complement of the human genome. Science, 298, 1912-1934
|
43 |
Mulder, K.M. (2000). Role of Ras and Mapks in TGF- signaling. Cytokine Growth Factor Rev., 11, 23-35
DOI
ScienceOn
|
44 |
Oft, M., Peli, J., Rudaz, C., Schwarz, H., Beug, H. and Reichmann, E. (1996). TGF-1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells. Genes Dev., 10, 2462-2477
DOI
ScienceOn
|
45 |
Markowitz, S.D. and Roberts, A.B. (1996). Tumor suppressor activity of the TGF- pathway in human cancers. Cytokine Growth Factor Rev., 7, 93-102
DOI
ScienceOn
|
46 |
Tucker, R.F., Shipley, G.D., Moses, H.L. and Holley, R.W. (1984). Growth inhibitor from BSC-1 cells closely related to platelet type beta transforming growth factor. Science, 226, 705-707
DOI
ScienceOn
|
47 |
Campbell, C.E., Flenniken, A.M., Skup, D. and Williams, B.R. (1991). Identification of a serum- and phorbol esterresponsive element in the murine tissue inhibitor of metalloproteinase gene. J. Biol. Chem., 266, 7199-7206
|
48 |
Saika, S., Kono-Saika, S., Ohnishi, Y., Sato, M., Muragaki, Y., Ooshima, A., Flanders, K.C., Yoo, J., Anzano, M. and Liu, C.Y. (2004). Smad3 signaling is required for epithelialmesenchymal transition of lens epithelium after injury. Am. J. Pathol., 164, 651-663
DOI
ScienceOn
|
49 |
Giannelli, G., Bergamini, C., Fransvea, E., Sgarra, C. and Antonaci, C. (2005). Laminin 5 with transforming growth factor- induces epithelial to mesenchymal transition in hepatocellular carcinoma. Gastroenterology, 129, 1375- 1383
DOI
ScienceOn
|
50 |
Maehara, Y., Kakeji, Y., Kabashima, A., Emi, Y., Watanabe, A., Akazawa, K., Baba, H., kohnoe, S. and Sugimachi, K. (1999). Role of transforming growth factor-1 in invasion and metastasis in gastric carcinoma. J. Clin. Oncol., 17, 607-614
DOI
|
51 |
Blobe, G.C., Schiemann, W.P. and Lodish, H.F. (2000). Role of transforming growth factor in human disease. N. Engl. J. Med., 342, 1350-1358
DOI
ScienceOn
|
52 |
Shi, Y. and Massague, J. (2003). Mechanisms of TGF- signaling from cell membrane to the nucleus. Cell, 113, 685- 700
DOI
ScienceOn
|
53 |
Li, W., Qiao, W., Chen, L., Xu, X., Yang, X., Li, D., Li, C., Brodie, S.G., Meguid, M.M. and Hennighausen, L. (2003). Squamous cell carcinoma and mammary abscess formation through squamous metaplasia in Smad4/Dpc4 conditional knockout mice. Development, 130, 6143-6153
DOI
ScienceOn
|
54 |
Marshall, M.S. (1995). Ras target proteins in eukaryotic cells. FASEB J., 9, 1311-1318
DOI
|
55 |
Moses, H.L., Tucker, R.F., Leof, E.B., Coffey, R.J. Jr., Halper, J. and Shipley, G.D. (1985). Type- transforming growth factor is a growth stimulator and a growth inhibitor (Feramisco, J., Ozanne, B and Stiles, C. Eds.). Cold Spring Harbor Laboratories., New York, pp 65-71
|
56 |
Kitagawa, K., Murata, A., Matsuura, N., Tohya, K., Takaichi, S., Monden, M. and Inoue, M. (1996). Epithelial-mesenchymal transformation of a newly established cell line from ovarian adenosarcoma by transforming growth factor-1. Int. J. Cancer., 66, 91-97
DOI
|
57 |
Tian, F., DaCosta Byfield, S., Parks, W.T., Yoo, S., Felici, A., Tang, B., Piek, E., Wakefield, L.M. and Roberts, A.B. (2003). Reduction in Smad2/3 signaling enhances tumorigenesis but suppresses metastasis of breast cancer cell lines. Cancer Res., 63, 8284-8292
|
58 |
Iglesias, M., Frontelo, P., Gamallo, C. and Quintanilla, M. (2000). Blockade of Smad4 in transformed keratinocytes containing a Ras oncogene leads to hyperactivation of the Ras-dependent Erk signalling pathway associated with progression to undifferentiated carcinomas. Oncogene, 19,4134-4145
DOI
|
59 |
Boyer, B., Valles, A.M. and Edme, N. (2000). Induction and regulation of epithelial-mesenchymal transitions. Biochem. Pharmacol., 60, 1091-1099
DOI
ScienceOn
|
60 |
Kim, E.S., Sohn, Y.W. and Moon, A. (2007). TGF--induced transcriptional activation of MMP-2 is mediated by activating transcription factor (ATF)2 in human breast epithelial cells. Cancer Lett., 252, 147-156
DOI
ScienceOn
|
61 |
Mulder, K.M. and Morris, S.L. (1992). Activation of p21ras by transforming growth factor in epithelial cells. J. Biol. Chem., 267, 5029-5031
|
62 |
Muraoka, R.S., Dumont, N., Ritter, C.A., Dugger, T.C., Brantley, D.M. and Chen, J. (2002). Blockade of TGF- inhibits mammary tumor cell viability, migration, and metastases. J. Clin. Invest., 109, 1551-1559
DOI
|
63 |
Sehgal, I. and Thompson, T.C. (1999). Novel regulation of type IV collagenase (matrix metalloproteinase-9 and -2) activities by transforming growth factor-1 in human prostate cancer cell lines. Mol. Biol. Cell., 10, 407-416
DOI
|
64 |
Forrester, E., Chytil, A., Bierie, B., Aakre, M., Gorska, A.E., Sharif-Afshar, A.R., Muller, W.J. and Moses, H.L. (2005). Effect of conditional knockout of the type II TGF receptor gene in mammary epithelia on mammary gland development and polyomavirus middle Tantigen induced tumor formation and metastasis. Cancer Res., 65, 2296-23
DOI
ScienceOn
|
65 |
Bhowmick, N.A., Ghiassi, M., Bakin, A., Aakre, M., Lundquist, C.A., Engel, M.E., Arteaga, C.L. and Moses, H.L. (2001). Transforming growth factor- mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism. Mol. Biol. Cell., 12, 27-36
DOI
|
66 |
Frixen, U.H., Behrens, J., Sachs, M., Eberle, G., Voss, B., Warda, A., Lochner, D. and Birchmeier, W. (1991). E-Cadherin- mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. J. Cell. Biol., 113, 173-185
DOI
|
67 |
Schwarz, L.C., Gingras, M.C., Goldberg, G., Greenberg, A.H. and Wright, J.A. (1988). Loss of growth factor dependence and conversion of transforming growth factor-1 inhibition to stimulation in metastatic H-ras-transformed murine fibroblasts. Cancer Res., 48, 6999-7003
|
68 |
Sternlicht, M.D., Lochter, A., Sympson, C.J., Huey, B., Rougier, J.P. and Gray, J.W. (1999). The stromal proteinase MMP3/ stromelysin-1 promotes mammary carcinogenesis. Cell, 98, 137-146
DOI
ScienceOn
|
69 |
Bourne, H.R., Sanders, D.A. and McCormick, F. (1991). The GTPase superfamily: conserved structure and molecular mechanism. Nature, 349, 117-127
DOI
ScienceOn
|
70 |
Fidler, I.J. (1990). Critical factors in the biology of human cancer metastasis. Cancer Res., 50, 6130-6138
|
71 |
Johansson, N., Ala-aho, R., Uitto, V., Grenman, R., Fusenig, N.E. and Lopez-Otin, C. (2000). Expression of collagenase- 3 (MMP-13) and collagenase-1 (MMP-1) by transformed keratinocytes is dependent on the activity of p38 mitogenactivated protein kinase. J. Cell. Sci., 113, 227-235
|
72 |
Liotta, L.A. and Stetler-Stevenson, W.G. (1991). Tumor invasion and metastasis: an imbalance of positive and negative regulation. Cancer Res., 51, 5054-5059
|
73 |
Portella, G., Cumming, S.A., Liddell, J., Cui, W., Ireland, H., Akhurst, R.J. and Balmain, A. (1998). Transforming growth factor is essential for spindle cell conversion of mouse skin carcinoma in vivo: implications for tumor invasion. Cell Growth Differ., 9, 393-404
|
74 |
Wick, W., Platten, M. and Weller, M. (2001). Glioma cell invasion: regulation of metalloproteinase activity by TGF-. J. Neurooncol., 53, 177-185
DOI
ScienceOn
|
75 |
Yin, J.J., Selander, K., Chirgwin, J.M., Dallas, M., Grubbs, B.G., Wieser, R., Massague, J., Mundy, G.R. and Guise, T.A. (1999). TGF- signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development. J. Clin. Invest., 103, 197-206
DOI
ScienceOn
|
76 |
Clair, T., Miller, W.R. and Cho-Chung, Y.S. (1987). Prognostic significance of the expression of a ras protein with a molecular weight of 21,000 by human breast cancer. Cancer Res., 47, 5290-5293
|
77 |
Elliott, R.L. and Blobe, G.C. (2005). Role of transforming growth factor in human cancer. J. Clin. Oncol., 23, 2078-2093
DOI
ScienceOn
|
78 |
Lee, J.M., Dedhar, S., Kalluri, R. and Thompson, E.W. (2006). The epithelial-mesencymal transiton: new insights in signaling, development, and disease. J. Cell Biol., 172, 973-977
DOI
ScienceOn
|
79 |
Ionescu, A.M., Schwarz, E.M., Zuscik, M.J., Drissi, H., Puzas, J.E., Rosier, R.N. and O'Keefe, R.J. (2003). ATF2 cooperates with Smad3 to mediate TGF- effects on chondrocyte maturation. Exp. Cell Res., 288, 198-207
DOI
ScienceOn
|
80 |
Ellenrieder, V., Hendler, S.F., Ruhland, C., Boeck, W., Adler, G. and Gress, T.M. (2001). TGF--induced invasiveness of pancreatic cancer cells is mediated by matrix metalloproteinase- 2 and the urokinase plasminogen activator system. Int. J. Cancer., 93, 204-211
DOI
ScienceOn
|
81 |
Kim, E.S., Kim, M.S. and Moon, A. (2004). TGF--induced upregulation of MMP-2 and MMP-9 depends on p38 MAPK, but not ERK signaling in MCF10A human breast epithelial cells. Int. J. Oncol., 25, 1375-1382
|
82 |
Roberts, A.B. and Sporn, M.B. (1990). Peptide growth factors and their receptors-Handbook of experimental pharmacology (Sporn, M.B and Roberts, A.B. Eds.). Springer, Heidelberg, pp. 419-472
|
83 |
Santibanez, J.F., Guerrero, J., Quintanilla, M., Fabra, A. and Martinez, J. (2002). Transforming growth factor-1 modulates matrix metalloproteinase-9 production through the Ras/MAPK signaling pathway in transformed keratinocytes. Biochem. Biophys. Res. Commun., 296, 267-273
DOI
ScienceOn
|
84 |
Yu, L., Hebert, M.C. and Zhang, Y.E. (2002). TGF- receptoractivated p38 MAP kinase mediates Smad-independent TGF- responses. EMBO J., 21, 3749-3759
DOI
ScienceOn
|
85 |
Lin, S.W., Lee, M.T., Ke, F.C., Lee, P.P., Huang, C.J. and Ip, M.M. (2000). TGFa1 stimulates the secretion of matrix metalloproteinase 2 (MMP2) and the invasive behavior in human ovarian cancer cells, which is suppressed by MMP inhibitor BB3103. Clin. Exp. Metastasis., 18, 493-499
DOI
|
86 |
de Caestecker, M.P., Piek, E. and Roberts, A.B. (2000). Role of transforming growth factor- signaling in cancer. J. Natl. Cancer Inst., 92, 1388-1402
DOI
ScienceOn
|
87 |
Derynck, R. and Zhang, Y.E. (2003). Smad-dependent and Smad-independent pathways in TGF- family signalling. Nature, 425, 577-584
DOI
ScienceOn
|
88 |
Itoh, S., Thorikay, M., Kowanetz, M., Moustakas, A., Itoh, F., Heldin, C.H. and ten Dijke, P. (2003). Elucidation of Smad requirement in transforming growth factor- type I receptor- induced responses. J. Biol. Chem., 278, 3751-3761
DOI
ScienceOn
|
89 |
Massague, J. (2000). How cells read TGF- signals. Nat. Rev. Mol. Cell Biol., 1, 169-178
DOI
ScienceOn
|
90 |
Oft, M., Heider, K.H. and Beug, H. (1998). TGF- signaling is necessary for carcinoma cell invasiveness and metastasis. Curr. Biol., 8, 1243-1252
DOI
ScienceOn
|
91 |
Oft, M., Akhurst, R.J. and Balmain, A. (2002). Metastasis is driven by sequential elevation of H-ras and Smad2 levels. Nat. Cell. Biol., 4, 487-494
|
92 |
Roberts, A.B., Anzano, M.A., Wakefield, L.M., Roche, N.S., Stern, D.F. and Sporn, M.B. (1985). Type transforming growth factor: A bifunctional regulator of cellular growth. Proc. Natl. Acad. Sci. U.S.A., 82, 119-123
|
93 |
Siegel, P.M., Shu, W., Cardiff, R.D., Muller, W.J. and Massague, J. (2003). Transforming growth factor signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis. Proc. Natl. Acad. Sci. U.S.A., 100, 8430-8435
|
94 |
Welch, D.R., Fabra, A. and Nakajima, M. (1990). Transforming growth factor stimulates mammary adenocarcinoma cell invasion and metastatic potential. Proc. Natl. Acad. Sci. U.S.A., 87, 7678-7682
|
95 |
Yan, Z., Winawer, S. and Friedman, E. (1994). Two different signal transduction pathways can be activated by transforming growth factor 1 in epithelial cells. J. Biol. Chem., 269, 13231-13237
|
96 |
Thiery, J.P. and Chopin, D. (1999). Epithelial cell plasticity in development and tumor progression. Cancer Metastasis Rev., 18, 31-42
DOI
ScienceOn
|
97 |
Sato, H., Takino, T., Okada, Y., Cao, J., Shinagawa, A. and Yamamoto, E. (1994). A matrix metalloproteinase expressed on the surface of invasive tumor cells. Nature, 370, 61-65
DOI
ScienceOn
|
98 |
Alexandrow, M.G. and Moses, H.L. (1995). Transforming growth factor and cell cycle regulation. Cancer Res., 55, 1452- 1457
|
99 |
Mauviel, A., Chung, K.Y., Agarwal, A., Tamai, K. and Uitto, J. (1996). Cell-specific induction of distinct oncogenes of the Jun family is responsible for differential regulation of collagenase gene expression by transforming growth factor- in fibroblasts and keratinocytes. J. Biol. Chem., 271, 10917-10923
DOI
ScienceOn
|
100 |
Platten, M., Wick, W. and Weller, M. (2001). Malignant glioma biology: role for TGF- in growth, motility, angiogenesis, and immune escape. Microsc. Res. Tech., 52, 401-410
DOI
ScienceOn
|
101 |
Thiery, J.P. (2002). Epithelial-mesenchymal transitions in development and pathologies. Curr. Opin. Cell Biol., 15, 740-746
DOI
ScienceOn
|