1 |
Bae, E.J., Cho, M.J. and Kim, S.G. (2007). Metformin prevents an adaptive increase in GSH and induces apoptosis under the conditions of GSH deficiency in H4IIE cells. J. Toxicol. Environ. Health, in press
|
2 |
Kang, K.W., Lee, S.J., Park, J.W. and Kim, S.G. (2002). Phosphatidylinositol 3-kinase regulates nuclear translocation of NF-E2-related factor 2 through actin rearrangement in response to oxidative stress. Mol. Pharmacol., 62, 1001-1010
DOI
ScienceOn
|
3 |
Klepser, T.B. and Kelly, M.W. (1997). Metformin hydrochloride, an antihyperglycemic agent. Am. J. Health Syst. Pharm., 54, 893-903
|
4 |
Meisse, D., VanCasteele, M., Beauloye, C., Hainault, I., Kefas, B.A., Rider, M.H., Foufelle, F. and Hue, L. (2002). Sustained activation of AMP activated protein kinase induces c-Jun N-terminal kinase activation and apoptosis in liver cells. FEBS Lett., 526, 38-42
DOI
ScienceOn
|
5 |
Ogasawara, T., Hoensch, H. and Ohnhaus, E.E. (1985). Distribution of glutathione and its related enzymes in small intestinal mucosa of rats. Arch. Toxicol. Suppl., 8, 110- 113
|
6 |
Park, I.N., Cho, I.J. and Kim, S.G. (2004). Ceramide negatively regulates glutathione S-transferase gene transactivation via repression of hepatic nuclear factor-1 that is degraded by the ubiquitin proteasome system. Mol. Pharmacol., 65, 1475-1484
DOI
ScienceOn
|
7 |
Pinkus, R., Weiner, L.M. and Daniel, V.J. (1996). Role of oxidants and antioxidants in the induction of AP-1, NF-B, and glutathione S-transferase gene expression. J. Biol. Chem., 271, 13422-13429
DOI
ScienceOn
|
8 |
Stephen, N.D., Insulin, oral hypoglycemic agents, and the pharmacology of the endocrine pancreas. In, Laurence, L.B., John, S.L., Keith, L.P., eds. Goodman & Gilman's The Pharmacological Basis of Therapeutics. 11th Edition. New York, McGraw-Hill (2006). pp. 1613-1646
|
9 |
Viollet, B., Andreelli, F., Jorgensen, S.B., Perrin, C., Geloen, A., Flamez, D., Mu, J., Lenzner, C., Baud, O., Bennoun, M., Gomas, E., Nicolas, G., Wojtaszewski, J.F., Kahn, A., Carling, D., Schuit, F.C., Birnbaum, M.J., Richter, E.A., Burcelin, R. and Vaulont, S. (2003). The AMP-activated protein kinase alpha2 catalytic subunit controls wholebody insulin sensitivity. J. Clin. Invest., 11, 91-98
|
10 |
Wilcock, C. and Bailey, C.J. (1994). Accumulation of metformin by tissues of the normal and diabetic mouse. Xenobiotica, 24, 49-57
DOI
ScienceOn
|
11 |
Park, E.Y., Cho, I.J. and Kim, S.G. (2004). Transactivation of the PPAR-responsive enhancer module in chemopreventive glutathione S-transferase gene by the peroxisome proliferator-activated receptor- and retinoid X receptor heterodimer. Cancer Res., 64, 3701-3713
DOI
ScienceOn
|
12 |
Kang, K.W., Cho, I.J., Lee, C.H. and Kim, SG. (2003). Essential role of phosphatidylinositol 3-kinase-dependent CCAAT/ enhancer binding protein beta activation in the induction of glutathione S-transferase by oltipraz. J. Natl. Cancer. Inst., 95, 53-66
DOI
ScienceOn
|
13 |
Kefas, B.A., Cai, Y., Kerckhofs, K., Ling, Z., Martens, G., Heimberg, H., Pipeleers, D. and Van de Casteele, M. (2004). Metformin-induced stimulation of AMP-activated protein kinase in beta-cells impairs their glucose responsiveness and can lead to apoptosis. Biochem. Pharmacol., 68, 409-416
DOI
ScienceOn
|
14 |
Kemp, B.E., Stapleton, D., Campbell, D.J., Chen, Z.P., Murthy, S., Walter, M., Gupta, A., Adams, J.J., Katsis, F., Van- Denderen, B., Jennings, I.G., Iseli, T., Michell, B.J. and Witters, L.A. (2003). AMP-activated protein kinase, super metabolic regulator. Biochem. Soc. Trans., 31, 162-168
DOI
|
15 |
Polekhina, G., Gupta, A., Michell, B.J., van Denderen, B., Murthy, S., Feil, S.C., Jennings, I.G., Campbell, D.J., Witters, L.A., Parker, M.W., Kemp, B.E. and Stapleton, D. (2003). AMPK beta subunit targets metabolic stress sensing to glycogen. Curr. Biol., 13, 867-871
DOI
ScienceOn
|
16 |
Kefas, B.A., Cai, Y., Heimberg, H., Hue, L., Pipeleers, D. and VanCasteele, M. (2003). AMP-activated protein kinase can induce apoptosis of insulin-producing MIN6 cells through stimulation of c-Jun-N-terminal kinase. J. Mol. Endocrinol., 30, 151-161
DOI
ScienceOn
|
17 |
Kang, K.W., Cho, M.K., Lee, C.H. and Kim, S.G. (2001). Activation of phosphatidylinositol 3-kinase and Akt by tertbutylhydroquinone is responsible for antioxidant response element-mediated rGSTA2 induction in H4IIE cells. Mol. Pharmacol., 59, 1147-1156
DOI
|
18 |
Paulson, K.E., Darnell, J.E. Jr., Rushmore, T. and Pickett, C.B. (1990). Analysis of the upstream elements of the xenobiotic compound-inducible and positionally regulated glutathione S-transferase Ya gene. Mol. Cell. Biol., 10, 1841-1852
DOI
|
19 |
Primiano, T., Egner, P.A., Sutter, T.R., Kelloff, G.J., Roebuck, B.D. and Kensler, T.W. (1995). Intermittent dosing with oltipraz, relationship between chemoprevention of aflatoxininduced tumorigenesis and induction of glutathione Stransferases. Cancer Res., 55, 4319-4324
|
20 |
Wilcock, C., Wyre, N.D. and Bailey, C.J. (1991). Subcellular distribution of metformin in rat liver. J. Pharm. Pharmacol., 43, 442-444
DOI
|
21 |
Kang, K.W., Ryu, J.H. and Kim, S.G. (2000). The essential role of phosphatidylinositol 3-kinase and of p38 mitogenactivated protein kinase activation in the antioxidant response element-mediated rGSTA2 induction by decreased glutathione in H4IIE hepatoma cells. Mol. Pharmacol., 58, 1017-1025
DOI
|
22 |
Bolton, J.L., Thompson, J.A., Allentoff, A.J., Miley, F.B. and Malkinson, A.M. (1993). Metabolic activation of butylated hydroxytoluene by mouse bronchiolar Clara cells. Toxicol. Appl. Pharmacol., 123, 43-49
DOI
ScienceOn
|
23 |
Villafania, A., Anwar, K., Amar, S., Chie, L., Way, D., Chung, D.L., Adler, V., Ronai, Z., Brandt-Rauf, P.W., Yamaizumii, Z., Kung, H.F. and Pincus, M.R. (2000). Glutathione-STransferase as a selective inhibitor of oncogenic ras-p21- induced mitogenic signaling through blockade of activation of Jun by Jun-N-terminal kinase. Ann. Clin. Lab. Sci., 30, 57-64
|
24 |
Hermann, L.S. (1979). Metformin, a review of its pharmacological properties and therapeutic use. Diabet. Metab., 5, 233-245
|
25 |
Hardie, D.G. (2003). Minireview, The AMP-activated protein kinase cascade, the key sensor of cellular energy status. Endocrinology, 144, 5179-5183
DOI
ScienceOn
|
26 |
Jeyapaul, J. and Jaiswal, A.K. (2000). Nrf2 and c-Jun regulation of antioxidant response element (ARE)-mediated expression and induction of -glutamylcysteine synthetase heavy subunit gene. Biochem. Pharmacol., 59, 1433- 1439
DOI
ScienceOn
|