Gene Expression Profiling in Diethylnitrosamine Treated Mouse Liver: From Pathological Data to Microarray Analysis
![]() |
Kim, Ji-Young
(Korea Institute of Toxicology, Korea Research Institute of Chemical Technology)
Yoon, Seok-Joo (Korea Institute of Toxicology, Korea Research Institute of Chemical Technology) Park, Han-Jin (Korea Institute of Toxicology, Korea Research Institute of Chemical Technology) Kim, Yong-Bum (Korea Institute of Toxicology, Korea Research Institute of Chemical Technology) Cho, Jae-Woo (Korea Institute of Toxicology, Korea Research Institute of Chemical Technology) Koh, Woo-Suk (Korea Institute of Toxicology, Korea Research Institute of Chemical Technology) Lee, Michael (Department of Biology, College of Natural Sciences, University of Incheon) |
1 | Ben-Zur, T., Feige, E., Motro, B. and Wides, R. (2000). The mammalian Odz gene family: Homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles. Dev. Biol., 217, 107-120 DOI ScienceOn |
2 | Garrow, T.A., Brenner, A.A., Whitehead, V.M., Chen, X.-N., Duncan, R.G., Korenberg, J.R. and Shane, B. (1993). Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localization. J. Biol. Chem., 268, 11910-11916 |
3 | Kaasik, K. and Lee, C.C. (2004). Reciprocal regulation of haem biosynthesis and the circadian clock in mammals. Nature, 430, 467-471 DOI ScienceOn |
4 | Oyake, T., Itoh, K., Motohashi, H., Hayashi, N., Hoshino, H., Nishizawa, M., Yamamoto, M. and Igarashi, K. (1996). Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site. Mol. Cell. Biol., 16, 6083-6095 DOI |
5 | Petit, M.M.R., Mols, R., Schoenmakers, E.F.P.M., Mandahl, N. and Van de Ven, W.J.M. (1996). LPP, the preferred fusion partner gene of HMGIC in lipomas, is a novel member of the LIM protein gene family. Genomics, 36, 118-129 DOI ScienceOn |
6 | Qian, C., Idoate, M., Bilbao, R., Sangro, B., Bruna, O., Vazquez, J. and Prieto, J. (1997). Gene transfer and therapy with adenoviral vector in rats with diethylnitrosamineinduced hepatocellular carcinoma. Human Gene Ther., 8, 349-358 DOI ScienceOn |
7 | Williams, G.M., Iatropoulos, M.J., Wang, C.X., Ali, N., Rivenson, A., Peterson, L.A., Schulz, C. and Gebhardt, R. (1996). Diethylnitrosamine exposure-responses for DNA damage, centrilobular cytotoxicity, cell proliferation and carcinogenesis in rat liver exhibit some non-linearities. Carcinogenesis, 17, 2253-2258 DOI ScienceOn |
8 | Schoenherr, C.J. and Anderson, D.J. (1995). The neuronrestrictive silencer factor (NRSF): A coordinate repressor of multiple neuron-specific genes. Science, 267, 1360- 1363 DOI ScienceOn |
9 | Smart, D.E., Green, K., Oakley, F., Weitzman, J.B., Yaniv, M.,Reynolds, G., Mann, J., Millward-Sadler, H. and Mann, D.A. (2006). JunD is a profibrogenic transcription factor regulated by Jun N-terminal kinase-independent phosphorylation. Hepatology, 44, 1432-1440 DOI ScienceOn |
10 | Pennie, W.D. and Kimber, I. (2002). Toxicogenomics: transcript profiling and potential application to chemical allergy. Toxicol. In Vitro, 16, 319-326 DOI ScienceOn |
11 |
Tatematsu, M., Nagamine, Y. and Farber, E. (1988). Stable phenotypic expression of glutathione S-transferase placental type and unstable phenotypic expression of |
12 | Momand, J., Zambetti, G.P., Olson, D.C., George, D.L. and Levine, A.J. (1992). The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell, 69, 1237-1245 DOI ScienceOn |
13 |
Yokoyama-Kobayashi, M., Saeki, M., Sekine, S. and Kato, S. (1997). Human cDNA encoding a novel TGF- |
14 | Connor, F., Wright, E., Denny, P., Koopman, P. and Ashworth, A. (1995). The Sry-related HMG box-containing gene Sox6 is expressed in the adult testis and developing nervous system of the mouse. Nucleic Acids Res., 23, 3365-3372 DOI |
15 |
Bishop, D.F., Henderson, A.S. and Astrin, K.H. (1990). Human |
16 | Driver, H.E. and McLean, A.E. (1986). Dose-response relationships for initiation of rat liver tumours by diethylnitrosamine and promotion by phenobarbitone or alcohol. Food Chem. Toxicol., 24, 241-245 DOI ScienceOn |
17 | Waring, J.F., Jolly, R.A., Ciurlionis, R., Lum, P.Y., Praestgaard, J.T., Morfitt, D.C., Buratto, B., Roberts, C., Schadt, E. and Ulrich, R.G. (2001). Clustering of hepatotoxins based on mechanism of toxicity using gene expression profiles. Toxicol. Appl. Pharmacol., 175, 28-42 DOI ScienceOn |
18 | Nakae, D., Kobayashi, Y., Akai, H., Andoh, N., Satoh, H., Ohashi, K., Tsutsumi, M. and Konishi, Y. (1997). Involvement of 8-hydroxyguanine formation in the initiation of rat liver carcinogenesis by low dose levels of N-nitrosodiethylamine. Cancer Res., 57, 1281-1287 |
19 | Wang, J.-W., Howson, J., Haller, E. and Kerr, W.G. (2001a). Identification of a novel lipopolysaccharide-inducible gene with key features of both a kinase anchor proteins and chs1/beige proteins. J. Immunol., 166, 4586-4595 DOI |
20 | Wang, Y., Devereux, W., Stewart, T.M. and Casero, R.A. Jr. (2001b). Characterization of the interaction between the transcription factors human polyamine modulated factor (PMF-1) and NF-E2-related factor 2 (Nrf-2) in the transcriptional regulation of the spermidine/spermine N(1)- acetyltransferase (SSAT) gene. Biochem. J., 355, 45-49 DOI |
21 | Fielden, M.R. and Zacharewski, T.R. (2001). Challenges and limitations of gene expression profiling in mechanistic and predictive toxicology. Toxicol. Sci., 60, 6-10 DOI ScienceOn |
22 | Lamour, V., Quevillon, S., Diriong, S., N'Guyen, V.C., Lipinski, M. and Mirande, M. (1994). Evolution of the Glx-tRNA synthetase family: The glutaminyl enzyme as a case of horizontal gene transfer. Proc. Nat. Acad. Sci. U.S.A., 91, 8670-8674 |
23 | Uchida, S., Kwon, H.M., Yamauchi, A., Preston, A.S., Marumo, F. and Handler, J.S. (1992). Molecular cloning of the cDNA for an MDCK cell Na(+)- and Cl(-)-dependent taurine transporter that is regulated by hypertonicity. Proc. Nat. Acad. Sci. U.S.A., 89, 8230-8234 |
24 | Bach, I. (2000). The LIM domain: Regulation by association. Mech. Dev., 91, 5-17 DOI ScienceOn |
25 | Shivapurkar, N., Hoover, K.L. and Poirier, L.A. (1986). Effect of methionine and choline on liver tumor promotion by phenobarbital and DDT in diethylnitrosamine-initiated rats. Carcinogenesis, 547-550 |
26 | Qin, L.X. and Tang, Z.Y. (2002). The prognostic molecular markers in hepatocellular carcinoma. World J. Gastroenterol., 8, 385-392 DOI |
27 | Bannasch, P., Hacker, H.J., Klimek, F. and Mayer, D. (1984). Hepatocellular glycogenosis and related pattern of enzymatic changes during hepatocarcinogenesis. Adv. Enzyme Regul., 22, 97-121 DOI ScienceOn |
28 | LeBoeuf, R.A., Laishes, B.A. and Hoekstra, W.G. (1985).Effects of dietary selenium concentration on the development of enzyme-altered liver foci and hepatocellular carcinoma induced by diethylnitrosamine or N-acetylaminofluorene in rats. Cancer Res., 45, 5489-5495 |
29 | Brown, P.O. and Botstein, D. (1999). Exploring the new world of the genome with DNA microarrays. Nat. Genet., 21, 33-37 DOI ScienceOn |
30 | Eisen, M.B., Spellman, P.T., Brown, P.O. and Bostein, D. (1998). Cluster analysis and display of genome-wide expression patterns. Proc. Natl. Acad. Sci. U.S.A., 95, 14863-14868 |
31 | Yeung, K.Y. and Ruzzo, W.L. (2001). Principal component analysis for clustering gene expression data. Bioinformatics, 17, 763-774 DOI ScienceOn |
![]() |