Cadmium Induces Cell Cycle Arrest and Change in Expression of Cell Cycle Related Proteins in Breast Cancer Cell Lines |
Lee Young Joo
(Endocrine Toxicology Division, National Institute of Toxicological Research, Department of Food and Nutrition, and Research Institute of Human Ecology, Seoul National University)
Kang Tae Seok (Endocrine Toxicology Division, National Institute of Toxicological Research) Kim Tae Sung (Endocrine Toxicology Division, National Institute of Toxicological Research) Moon Hyun Ju (Endocrine Toxicology Division, National Institute of Toxicological Research) Kang Il Hyun (Endocrine Toxicology Division, National Institute of Toxicological Research) Oh Ji Young (Endocrine Toxicology Division, National Institute of Toxicological Research) Kwon Hoonjeong (Department of Food and Nutrition, and Research Institute of Human Ecology, Seoul National University) Han Soon Young (Endocrine Toxicology Division, National Institute of Toxicological Research) |
1 | Garcia-Morales, P., Saceda, M., Kenney, N., Kim, N., Salomon, D.S., Gottardis, M.M., Solomon, H.B., Sholler, P.F., Jordan, V.C. and Martin, M.B. (1994): Effect of cadmium on estrogen receptor levels and estrogen-induced responses human breast cancer cells. J. Biol. Chem., 269, 16896-16901 |
2 | Park, K.S., Ahn, Y., Kim, J.A., Yun, M.S., Seong, B.L. and Choi, K.Y. (2002): Extracellular zinc stimulates ERK-dependent activation of p21Cip/WAF1 and inhibits proliferation of colorectal cancer cells. Br. J. Pharmacol., 137, 597-607 DOI ScienceOn |
3 | Warren, S., Patel, S. and Kapron, C.M. (2000): The effect of vitamin E exposure on cadmium toxicity in mouse embryo cells in vitro. Toxicology, 142, 119-126 DOI ScienceOn |
4 | Koizumi, S. and Yamada, H. (2003): DNA microarray analysis of altered gene expression in cadmium-exposed human cells. J. Occup. Health, 45, 331-334 DOI ScienceOn |
5 | Zimmermann, K.C., Bonzon, C. and Green, D.R. (2001): The machinery of programmed cell death. Pharmacol. Ther., 92, 57-70 DOI ScienceOn |
6 | IARC (1993): Beryllium, cadmium, mercury and exposures in the glass manufacturing industry. In IARC Monographs on the Evaluation of Carcinogenic Risks to Human, 58, 41117, International Agency for Research on Cancer, Lyon |
7 | Kim, M.S., Kim, B.J., Woo, H.N., Kim, K.W., Kim, K.B., Kim, I.K. and Jung, Y.K. (2000): Cadmium induces caspase-mediated cell death: suppression by Bcl-2. Toxicology, 145, 27-37 DOI ScienceOn |
8 | Waalkes, M.P. (2000): Cadmium carcinogenesis in review. J. Inorg. Biochem., 79, 241-4 DOI ScienceOn |
9 | Stohs, S.J. and Bagchi, D. (1995): Oxidative mechanisms in the toxicity of metal ions. Free Radic. Biol. Med., 18, 321-336 DOI ScienceOn |
10 | Chao, J.I. and Yang, J.L. (2001): Opposite roles of ERK and p38 Mitogen-Activated Protein Kinases in cadmiuminduced genotoxicity and mitotic arrest. Chem. Res. Toxicol., 14, 1193-1202 DOI ScienceOn |
11 | Sarkar, S., Yadav, P. and Bhatnagar, D. (1998): Lipid peroxidative damage on cadmium exposure and alterations in antioxidant system in rat erythrocytes: a study with relation to time. Biometals, 11, 153-157 DOI ScienceOn |
12 | Waalkes, M.P. and Diwan, B.A. (1999): Cadmium-induced inhibition of the growth and metastasis of human lung carcinoma xenografts: role of apoptosis. Carcinogenesis, 20, 65-70 DOI ScienceOn |
13 | Son, M.H., Kang, K.W., Lee, C.H. and Kim, S.G. (2001): Potentiation of cadmium-induced cytotoxicity by sulfur amino acid deprivation through activation of exracellular signalregulated kinase 1/2 (ERK1/2) in conjunction with p38 kinase or c-jun N terminal kinase (JNK). Complete inhibition of the potentiated toxicity by U0126 and ERK1/2 and p38 kinase inhibitor. Biochem. Pharmacol., 62, 1379-1390 DOI ScienceOn |
14 | Chuang, S.M., Wang, I.C. and Yang, J.L. (2000): Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmium. Carcinogenesis, 21, 1423-1432 DOI ScienceOn |
15 | Pietenpol, J.A. and Stewart, Z.A. (2002): Cell cycle checkpoint signaling: cell cycle arrest versus apoptosis. Toxicology, 181-182, 475-481 DOI PUBMED ScienceOn |
16 | Hsu, P.C., Liu, M.Y., Hsu, C.C., Chen, L.Y. and Guo, Y.L. (1998): Effects of vitamin E and/or C on reactive oxygen species-related lead toxicity in the rat sperm. Toxicology, 128, 169-179 DOI ScienceOn |
17 | Szuster-Ciesielska, A., Stachura, A., Siotwinska, M., Kaminska, T., Sniezko, R., Paduch, R., Abramczyk, D., Filar, J. and Kandefer-Szerszen, M. (2000): The inhibitory effect of zinc on cadmium-induced cell apoptosis and reactive oxygen species (ROS) production in cell cultures. Toxicology, 145, 159-171 DOI PUBMED ScienceOn |
18 | Yuan, C., Kadiiska, M., Achanzar, W.E., Mason, R.P. and Waalkes, M.P. (2000): Possible role of caspase-3 inhibition in cadmium-induced blockage of apoptosis. Toxicol. Appl. Pharmacol., 164, 321-329 DOI ScienceOn |