Ozone Inhalation with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)- 1-butanone and/or Dibutyl Phthalate Induced Cell Cycle Alterations via Wild-type p53 Instability in B6C3F1 Mice |
Kim, Min-Young
(College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National university)
Song, Kyung-Suk (College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National university) Park, Gun-Ho (College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National university) Kim, Hyun-Woo (College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National university) Park, Jin-Hong (College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National university) Kim, Jun-Sung (College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National university) Jin, Hwa (College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National university) Kook-Jong, Eu (College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National university) Cho, Hyun-Sun (College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National university) |
1 | Hoffmann, D. and Hecht, S.S. (1985): Nicotine-derived N-nit-rosamines and tobacco related cancer; current status and future directions, Cancer Res., 45, 935-944 |
2 | Lee, C.C. and Fukushima, S. (1998): Alterations in cyclin D1, p53, and the cell cycle related elements: Implications for distinct genetic pathways of urinary bladder carcinogene-sis, Urol. Oncology, 4, 58-72 |
3 | Beniston, R.G. and Campo, M.S. (2003): Quercetin elevates p27(Kip1) and arrests both primary and HPV16 E6/E7 trans-formed human keratinocytes, Oncogene, 22, 5504-5514 |
4 | Stewart, N., Hicks, G.G., Praskevas, F. and Mowat, M. (1995): Evidence for a second cell cycle block at G2/M by p53. Oncogene, 10, 109-115 PUBMED |
5 | Waters, C.M., Littlewood, T.D., Hancock, D.C., Moore, J.P. and Evan, G.l. (1991): c-Myc protein expression in untrans-formed fibroblasts. Oncogene, 6, 797-805 PUBMED |
6 | Lewin, B. (1997): Cell cycle and growth regulation. In Lewin B editors, Genes VI, Oxford University Press, New York. U.S.A. |
7 | Hildesheim, J., Bulavin, D.V., Anver, M.R., Alvord, W.G., Hol-lander, M.C., Vardanian, L. and Fornace, A.J. Jr. (2002): Gadd45a protects against UV irradiation-induced skin tumors, and promotes apoptosis and stress signaling via MAPK and p53. Cancer Res., 62, 7305-7315 |
8 | Innocente, S.A., Abrahamson, J.L.A., Cogswell, J.P. and Lee, J.M. (1999): p53 regulates a G2 checkpoint through cyclin B1. Pro. Natl. Acad. Sci. USA, 96, 2147-2152 |
9 | Sonnenschein, C., Soto, A.M., Fernanfez, M.F., Olea, N., Olea-Serrano, M.F. and Ruiz-Lopez, M.D. (1995): Development of a marker of estrogenic exposure in human serum, Clin. Chem., 41, 1888-1895 |
10 | National Toxicology Program (NTP) (1995): Toxicity studies of Dibutyl Phthalate administered in feed F344/N rats and B6C3F1 mice. NTP Technical Report No. 30. U. S. Department of Health and Human Services. Public Health Service. National Institutes of Health. Research Triangle Park. N. C. 27709 |
11 | Skladanowski, A and Larsen, A. (1997): Expression of wild-type p53 increases etoposide cytotoxicity in M1 myeloid leukemia cells by facilitated G2 to M transition: implica-tions for gene therapy. Cancer Res., 57, 818-823 |
12 | Rocha, S., Martin, A.M., Meek, D.W. and Perkins, N.D. (2003): p53 Represses Cyclin D1 Transcription through Down Regulation of Bcl-3 and Inducing Increased Associ-ation of the p52 NF-kappaB Subunit with Histone Deacetylase 1. Mol Cell Biol., 23, 4713-4727 |
13 | Austian, J. (1973): Toxicity and health threats of phthalate esters: review of the literature, Environ. Health Perspect., 4, 3-26 |
14 | Harris, C.A., Henttu, P., Parker, M.G. and Sumpter, J.P. (1997): The estrogenic activity of phthalate esters in vitro, Environ. Health Perspect., 105, 802-811 |
15 | Masramon, L., Arribas, R. and Tortola, S. (1998): Moderate amplifications of the c-myc gene correlate with molecular and clinicopathological parameters in colorectal cancer. Br J Cancer, 77, 2349-2356 DOI PUBMED |
16 | Hecht, S.S. and Hoffmann, D. (1989): The relevance of tobacco-specific nitrosamines to human cancer, Cancer Surv., 8, 273-294 |
17 | Guillouf, C., Rosselli, F., Krishnaraju, K., Moustacchi, E., Hoff-man, B. and Liebermann, D.A. (1995): p53 involvement in control of G2 exist of the cell cycle: role in DNA damage-induced apoptosis. Oncogene, 10, 2263-2270 PUBMED |
18 | National Toxicology Program (NTP) (1994): Toxicology and carcinogenesis studies of ozone and ozone/ NNK in F344/N rats and B6C3F1 mice (inhalation studies). NTP Technical Report No. 440. U. S. Department of Health and Human Services. Public Health Service. National Institutes of Health. Research Triangle Park. N. C. 27709 |
19 | Kim, M.Y., Kim, Y.C. and Cho, M.H. (2002): Combined treatment with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and dibutyl phthalate enhances ozone-induced genotoxicity in B6C3F1 mice. Mutagenesis, 17, 331-336 |
20 | Ohtsuka, T., Ryu, H., Minamishima, Y.A., Ryo, A. and Lee, S.W. (2003): Modulation of p53 and p73 levels by cyclin G: implication of a negative feedback regulation. Onco-gene., 22, 1678-1687 |
21 | Leach, S.D., Scatena, C.D., Keefer, C.J., Goodman, H.A., Song, S.Y., Yang, L. and Pietenpol, J.A. (1998): Negative regulation of wee1 expression and cdc2 phosphorylation during p53-mediated growth arrest and apoptosis. Can-cer Res., 58, 3231-3236 |
22 | Lippmann, M. (1989): Health effects of ozone: a critical review, J. Am. Pollution control Assoc., 39, 672-695 |
23 | Jobling, S., Reynold, T., White, R., Parker, M.G. and Sumpter, J.P. (1995): A variety of environmentally persistent chemicals, including some phthalate plasticizer, are weakly estrogenic. Environ. Health Perspect., 103, 582-587 |
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