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Acute Oral Toxicity of G. bimaculatus in Rats  

김인선 (성균관대학교 약학대학 독성학교실)
안미영 (농업과학기술원 잠사곤충부)
류강선 (농업과학기술원 잠사곤충부)
이병무 (성균관대학교 약학대학 독성학교실)
Publication Information
Toxicological Research / v.18, no.4, 2002 , pp. 397-400 More about this Journal
Abstract
This study was carried out to investigate the acute toxicity of G. bimaculatus in Sprague-Dawley rats. G. bimaculatus was administered orally at doses of 8, 40, 200, 1000 and 5000 mg/kg. in this study, number of deaths, clinical sign, body weights, and pathological examination were investigated for 14 days after administration of G. bimaculatus. The results indicate that G. bimaculatus did not show any toxic effect in rats and oral $LD_{50}$ value was over 5000 mg/kg in Sprague-Dawley rats.
Keywords
Acute toxicity; G. bimaculato; $LD_{50}$values; Pathological examinations;
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Times Cited By KSCI : 5  (Citation Analysis)
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