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http://dx.doi.org/10.15188/kjopp.2019.10.33.5.295

Clinical Analysis of 194 Patients with Condyloma Applying Korean Medicine Treatment  

Yoon, Jung Jeh (Saengki Korean Medicine Clinic)
Jo, Su Ji (Saengki Korean Medicine Clinic)
Kim, Chul Yun (Saengki Korean Medicine Clinic)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.33, no.5, 2019 , pp. 295-301 More about this Journal
Abstract
The purpose of this study is to assess potential effects of the effects of Korean Medicine treatments on condyloma. Retrospective study of 194 patients with diagnosed condyloma in Saengki Korean Medicine Clinic from October 2013 to September 2018 was done. Patients were treated with Korean Medicine treatments such as herbal treatment, pharmacopuncture and moxibustion. The data has been analyzed by chi-squared distribution and t-test. A total of 194 patients were 148 males and 46 females. In the aspect of diagnosis, newly diagnosed patients were 96 and recurrent patients were 98. After the treatment, in the light of size complete clearances were 110 patients, partial clearances were 63 and non responses were 21. And in the light of number complete clearances were 110 patients, partial clearances were 68 and non responses were 16. In complete clearance group, the relation among the treatment period, sex, age, and the site of wart showed statistically significant. There were 3 recurrences of warts in the 6 months of follow-up observation for 110 of clearance group. No major side effects related to the treatment were found. As the result of t-test shows, the Korean Medicine treatment we had applied revealed as statistically effective on both number(t=11.471, p<.001) and size(t=11.951, p<.001) of the wart. The result of this study suggests that additional treatment of Korean medicine such as acupuncture and moxibustion treatment could be effective on condyloma patients.
Keywords
Clinical Analysis; Genital warts; Condyloma acuminatum; Korean Medicine;
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1 Lee SC, Clinician's Dermatology, Human Skin Science, Seoul, SNC Publishing, 2019;153-5, 369-70.
2 Sterling JC, Handfield-Jones S, Hudson PM. Guideline for the management of cutaneous warts. Br J Dermatol 2001;144:4-11.   DOI
3 World Health Organization. Human papillomavirus (HPV) and cervical cancer, World Health Organization 2016 Available from URL: http://www.who.int/mediacentre/factsheets/fs380/en/
4 Sandra AK, Analisa VH, Justin JG et al. Human papilloma virus infections. In: Fitzpatrick's dermatology in general medicine(Lowell AG, Stephen IK, Barbara AG et al.), 8th edn. The McGraw-Hill Companies, Inc., 2012;2421-33.
5 Drake LA, Ceilley RI, Cornelison RL, et al. Guidelines of care for warts: human papillomavirus. J Am Acad Dermatol 1995;32:98-103.   DOI
6 Seo YM, Lee KH. Synchronous Verrucous Carcinoma and Squamous Cell Carcinoma of Penis by Different Human Papillomavirus Infections, Korean J Urogenit Tract Infect Inflamm 2013;8(1):52-4.   DOI
7 Calmon MF, Tasso Mota M, Vassallo J, Rahal P. Penile carcinoma: risk factors and molecular alterations. Scientific World Journal 2011;11:269-82.   DOI
8 Heo J. Donguibogam(Principles and Practice of Eastern Medicine), Bubin publishers co. 1999:824-5.
9 C.J.N. Lacey, S.C. Woodhall, A. Wikstrom, J. Ross. 2012 European guideline for the management of anogenital warts, Journal of the European Academy of Dermatology and Venereology 2013;27:263-70.   DOI
10 Textbook Compilation Committee of National University of Traditional Korean Dermatology & Surgery. Text of Traditional Korean Dermatology & Surgery. 2007:432-4.
11 Yoon JM, Shin SH, Yoon HJ, Ko WS, A Statistical Study of Patients visited Wart Clinic, The Journal of Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology 2009;22(2):192-200.
12 Lee KY, Lee E, Cho NK, Korean Medicine Treatment for 326 patients with Genital Warts: Retrospective Chart Review, J Korean Med Ophthalmol Otolaryngol Dermatol 2015;28(4):196-207.   DOI
13 Lacey CJ, et al. Therapy for genital human papillomavirus-related disease. J Clin Virol. 2005;32(Suppl 1):82-90.   DOI
14 Luo M, Yu J, Zhu S, Huang L, Chen Y, Wei S. Detoxification therapy of traditional Chinese medicine for genital tract high-risk human papillomavirus infection: A systematic review and meta-analysis. PLoS ONE. 2019;14(3).
15 Chen X, Hu X, Liu L, Liang X, Xiao J. Extracts derived from a traditional Chinese herbal formula triggers necroptosis in ectocervical Ect1/E6E7 cells through activation of RIP1 kinase. Journal of Ethnopharmacology. 2019, 239, p 111922.   DOI