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http://dx.doi.org/10.15188/kjopp.2016.06.30.3.142

Effects of Fermented Rhus Verniciflua Stokes Extract on Diet-induced Hyperlipidemia in Rats  

Kim, Jeung Beum (Department of Pathology, College of Korean Medicine, Semyung University)
Kim, Tae Yeon (Department of Preventive Medicine, College of Korean Medicine, Semyung University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.30, no.3, 2016 , pp. 142-149 More about this Journal
Abstract
This study was designed to investigate the antihyperlipidemic activity of Fermented Rhus Verniciflua Stokes Extract(FRVSE) on diet-induced hyperlipidemia in rats. The animals were divided into 4 groups of the normal group(fed with normal diet), control group(fed with high fat diet), sample A group(fed with high fat diet and medicated FRVSE 192 ㎎/㎏/day), sample B group(fed with high fat diet and medicated FRVSE 384 ㎎/㎏/day), and received oral administration of each prescription with diet for a period of six weeks. The changes in the body weight, the liver weight, the epididymal fat weight, and the plasma levels of total cholesterol, triglyceride(TG), high density lipoprotein(HDL) cholesterol and low density lipoprotein(LDL) cholesterol were measured. In sample A group, the weight of liver and plasma level of TG decreased significantly. There was a significant decrease in the plasma level of total cholesterol, TG and LDL cholesterol in the sample B group. These results suggest that the FRVSE have a good antihyperlipidemic activity and a potential to treat hyperlipidemia.
Keywords
Fermented Rhus Verniciflua Stokes Extract(FRVSE); Hyperlipidemia; Total cholesterol; Triglyceride(TG); High density lipoprotein(HDL) cholesterol; Low density lipoprotein(LDL) cholesterol;
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