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http://dx.doi.org/10.15188/kjopp.2015.06.29.3.267

Anti-Obesity Effects of Lactic Acid Bacteria-Fermented Dioscoreae Rhizoma Powder on High Fat Diet-Fed Animal Model  

Park, Young Mi (Huvet Company Limited)
Oh, Hong Geun (Huvet Company Limited)
Kang, Yang Gyu (Huvet Company Limited)
Kim, Young Pill (Huvet Company Limited)
Sin, Hong Sig (Chebigen Incorporated)
Jang, Seung Hwan (Chebigen Incorporated)
Kim, Hee Jeong (Chebigen Incorporated)
Lee, Sang Wang (Chebigen Incorporated)
Lee, Hak Yong (Huvet Company Limited)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.29, no.3, 2015 , pp. 267-272 More about this Journal
Abstract
The purpose of this study was to examine the antiobesity effects of lactic acid bacteria-fermented Dioscoreae Rhizoma powder (LDR) in Sprague-Dawley rats with high-fat diet (HFD)-induced obesity. Rats were divided into 5 groups: normal diet group, control (high fat diet-vehicle) group, 0.4 g/kg LDR (high fat diet + 0.4 g/kg lactic acid bacteria-fermented Dioscoreae Rhizoma powder) group, 1 g/kg LDR (high fat diet + lactic acid bacteria-fermented Dioscoreae Rhizoma powder) group, 2.5g/kg LDR (high fat diet + lactic acid bacteria-fermented Dioscoreae Rhizoma powder) group. Our results indicate that LDR administration has effects on decreasing of body weight, fat weight, blood parameters and adipocyte size in the obesity animals. In addition, verified that fat degeneration and ballooning degeneration were alleviated in the experimental group fed on a high fat diet combined with LDR groups. These results indicate that lactic acid bacteria-fermented Dioscoreae Rhizoma powder may reduce elevating body weight and lipid accumulation in rat fed a high fat diet, suggesting its usefulness as a functional food for reducing body fat and obesity.
Keywords
Dioscoreae Rhizoma; lactic acid bacteria; anti-obesity; high fat diet; lipid accumulation;
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