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http://dx.doi.org/10.15188/kjopp.2015.02.29.1.72

Herbal Medicine Therapeutic Attempt for Diarrhea Induced by Carcinoid Symptoms of Rectosigmoid Neuroendocrine Tumor with Liver Metastasis Patient : a Case Report

Jeon, Hyung Joon (East-West Cancer Center, Dunsan Korean Hospital of Daejeon University)
Kim, Jong Min (East-West Cancer Center, Dunsan Korean Hospital of Daejeon University)
Cho, Chong Kwan (East-West Cancer Center, Dunsan Korean Hospital of Daejeon University)
Lee, Yeon Weol (East-West Cancer Center, Dunsan Korean Hospital of Daejeon University)
Yoo, Hwa Seung (East-West Cancer Center, Dunsan Korean Hospital of Daejeon University)

Publication Information

Journal of Physiology & Pathology in Korean Medicine / v.29, no.1, 2015 , pp. 72-78 More about this Journal

Abstract

This study aims to report a case of rectosigmoid neuroendocrine tumor patient with liver metastasis whose outstanding carcinoid symptom was mucosal diarrhea for more than 10 times a day. Three different herbal decoctions were administered orally for the treatment of diarrhea which was among carcinoid symptoms from diffuse metastatic liver lesion. The herbal decoctions given were modified Lijung-tang, modified Sambaek-tang and modified Jeokseokjiuyeoryang-tang. The administration period was 5, 14 and 9 days respectively. Frequency of patient's mucosal diarrhea had increased consistently during hospitalization. It had almost doubled compared to pre-hospitalization up to 27 times/24 hrs. But during the period of modified Sambaek-tang administration, frequency of diarrhea was maintained between 9 to 15 times/24hrs. There was no difference of liver tumors between Nov 16th 2013 and Dec 9th 2013 in computed tomography images. Three conventional established herbal prescriptions administered in this case didn't show any favorable effect on improving mucosal diarrhea induced by carcinoid symptoms of a rectosigmoid neuroendocrine tumor with liver metastasis. Even if modified Sambaek-tang showed partial effect on frequency of diarrhea, we concluded that it was not sufficient to be a therapeutic method of the diarrhea as carcinoid symptom. Furthermore, it is necessary to conduct additional studies about the diarrhea of neuroendocrine tumor with liver metastasis.

Keywords

neuroendocrine tumors; neoplasm metastasis; malignant carcinoid syndrome; diarrhea; herbal medicine;

Citations & Related Records

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