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http://dx.doi.org/10.17208/kjopp.2014.12.28.6.601

Effects of Acupuncture at the Wijung(BL40) and Chok-Samni(ST 36) on the Cerebral Blood Flow and Blood Pressure  

Jeong, Hyun Woo (College of Korean Medicine, Dongshin University)
Kim, Jin Woo (College of Korean Medicine, Dongshin University)
Han, Yang Shin (College of Korean Medicine, Dongshin University)
Jeong, Jong Gil (College of Korean Medicine, Dongshin University)
Choi, Chan Hun (College of Korean Medicine, Dongshin University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.28, no.6, 2014 , pp. 601-606 More about this Journal
Abstract
The purpose of this study is to research the effects of acupuncturing BL40 and ST36 and to determine the mechanism of action of acupuncturing BL40 and ST36 by measuring the changes of regional cerebral blood flow (rCBF) and mean arterial blood pressure (MABP) in normal rats. To determine the mechanism of action of acupuncturing BL40 and ST36, pretreatment with indomethacine and methylene blue was performed. Acupuncturing BL40 and ST36 significantly increased rCBF, and the increased rCBF by acupuncturing BL40 and ST36 was significantly inhibited by pretreatment with indomethacin (1 mg/kg, i.p.), an inhibitor of cyclooxygenase, and methylene blue($10{\mu}g/kg$, i.p.), an inhibitor of guanylate cyclase. Acupuncturing BL40 and ST36 decreased MABP, and decreased MABP by acupuncturing BL40 and ST36 was not changed by pretreatment with indomethacin and methylene blue. This result suggested that acupuncturing BL40 and ST36 might significantly increase rCBF by dilating arterial diameter and mechanism of acupuncturing BL40 and ST36 might be mediated by cyclooxygenase and guanylate cyclase.
Keywords
Wijung(BL40); Chok-Samni(ST36); regional cerebral blood flow (rCBF); mean arterial blood pressure (MABP);
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Times Cited By KSCI : 2  (Citation Analysis)
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