Effects of Bupleuri Radix on the Rat Hypothyroidism Induced by PTU (6-n-propyl-2-thiouracil) |
Kim, Seong Mo
(College of Oriental Medicine, Daegu Haany University)
Ku, Sae Kwang (College of Oriental Medicine, Daegu Haany University) Cho, Su Yeon (College of Oriental Medicine, Daegu Haany University) Park, Soo Jin (College of Oriental Medicine, Daegu Haany University) |
1 | Axelstad, M., Hansen, P.R., Boberg, J., Bonnichsen, M., Nellemann, C., Lund, S.P., Hougaard, K.S., Hass, U. Developmental neurotoxicity of propylthiouracil (PTU) in rats: relationship between transient hypothyroxinemia during development and long-lasting behavioural and functional changes. Toxicol Appl Pharmacol 232(1):1-13, 2008. DOI ScienceOn |
2 | Oner, J., Kukne,r A., Oner, H., Ozan, E., Yekeler, H. Effect of vitamin E on follicular cell proliferation and expression of apoptosis-associated factors in rats with 6-N-propyl-2-thiouracil-induced goitrogenesis. Folia Histochem Cytobiol 41(4):213-217, 2003. |
3 | Dory, L., Roheim, P.S. Rat plasma lipoproteins and apolipoproteins in experimental hypothyroidism. J Lipid Res 22(2):287-296, 1981. |
4 | Frost, P.H., Havel, R.J. Rationale for use of non-high-density lipoprotein cholesterol rather than low-density lipoprotein cholesterol as a tool for lipoprotein cholesterol screening and assessment of risk and therapy. Am J Cardiol 81(4A):26B-31B, 1998. DOI |
5 | Ito, M., Arishima, T., Kudo, T., Nishihara, E., Ohye, H., Kubota, S., Fukata, S., Amino, N., Kuma, K., Sasaki, I., Hiraiwa, T., Hanafusa, T., Takamatsu, J., Miyauchi, A. Effect of levo-thyroxine replacement on non-high-density lipoprotein cholesterol in hypothyroid patients. J Clin Endocrinol Metab 92(2):608-611, 2007. DOI |
6 | Teixeira, P.D.F., Reuters, V.S., Ferreira, M.M., Almeida, C.P., Reis, F.A., Buescu, A., Costa, A.J., Vaisman, M. Lipid profile in different degrees of hypothyroidism and effects of levothyroxine replacement in mild thyroid failure. Transl Res 151(4):224-231, 2008. DOI ScienceOn |
7 | Andreoli, T.E., Carpenter, C.J., Plum, F., Smith, L. Cecil Essentials of Medicine, Philadilphia: WB Saunder's Company, pp 436-437, 1986. |
8 | Feng, X., Jiang, Y., Melzer, P., Yen, P.M. Thyroid hormone regulation of hepatic genes in vivo detected by complementary DNA microarray. Mol Endocrinol 14(7):947-955, 2000. DOI ScienceOn |
9 | Simon-Giavarotti, K.A., Giavarotti, L., Gomes, L.F., Lima, A.F., Veridiano, A.M., Garcia, E.A., Mora, O.A., Fernandez, V., Videla, L.A., Junqueira, V.B. Enhancement of lindane-induced liver oxidative stress and hepatotoxicity by thyroid hormone is reduced by gadolinium chloride. Free Radic Res 36(10):1033-1039, 2002. DOI ScienceOn |
10 | Amin, A., Hamza, A.A. Oxidative stress mediates drug-induced hepatotoxicity in rats: a possible role of DNA fragmentation. Toxicology 208(3):367-375, 2005. DOI ScienceOn |
11 | Matsumoto, T., Sun, X.B., Hanawa, T., Kodaira, H., Ishii, K., Yamada, H. Effect of the antiulcer polysaccharide fraction from Bupleurum falcatum L. on the healing of gastric ulcer induced by acetic acid in rats. Phytother Res 16(1):91-93, 2002. DOI ScienceOn |
12 | Chattopadhyay, S., Sahoo, D.K., Subudhi, U., Chainy, G.B. Differential expression profiles of antioxidant enzymes and glutathione redox status in hyperthyroid rats: a temporal analysis. Comp Biochem Physiol C Toxicol Pharmacol 146(3):383-391, 2007. DOI ScienceOn |
13 | Williams, K.V., Nayak, S., Becker, D., Reyes, J., Burmeister, L.A. Fifty years of experience with propylthiouracil-associated hepatotoxicity: what have we learned? J Clin Endocrinol Metab 82(6):1727-1733, 1997. DOI ScienceOn |
14 | Guo, Y., Matsumoto, T., Kikuchi, Y., Ikejima, T., Wang, B., Yamada, H. Effects of a pectic polysaccharide from a medicinal herb, the roots of Bupleurum falcatum L. on interleukin 6 production of murine B cells and B cell lines. Immunopharmacology 49(3):307-316, 2000. DOI ScienceOn |
15 | Chang, W.C., Hsu, F.L. Inhibition of platelet activation and endothelial cell injury by flavan-3-ol and saikosaponin compounds. Prostaglandins Leukot Essent Fatty Acids 44(1):51-56, 1991. DOI ScienceOn |
16 | Nose, M., Amagaya, S., Ogihara, Y. Corticosterone secretion-inducing activity of saikosaponin metabolites formed in the alimentary tract. Chem Pharm Bull (Tokyo) 37(10):2736-2740, 1989. DOI ScienceOn |
17 | Niikawa, M., Sakai, Y., Ose, Y., Sato, T., Nagase, H., Kito, H., Sato, M., Mizuno, M. Enhancement of the mutagenicity of Trp-P-1, Trp-P-2 and benzo[a]pyrene by bupleuri radix extract. Chem Pharm Bull (Tokyo) 38(7):2035-2039, 1990. DOI ScienceOn |
18 | 문진영, 최미정, 남경수, 임종국. 柴胡가 free radical에 의한 脂質過酸化物 生成에 미치는 效果. 東國論集 15: 361-375, 1996. |
19 | Kavutcu, M., Canbolat, O., Ozturk, S., Olcay, E., Ulutepe, S., Ekinci, C., Gokhun, I.H., Durak, I. Reduced enzymatic antioxidant defense mechanism in kidney tissues from gentamicin-treated guinea pigs: effects of vitamins E and C. Nephron 72(2):269-274, 1996. DOI |
20 | Matsumoto, T., Moriguchi, R., Yamada, H. Role of polymorphonuclear leucocytes and oxygen-derived free radicals in the formation of gastric lesions induced by HCl/ethanol, and a possible mechanism of protection by anti-ulcer polysaccharide. J Pharm Pharmacol 45(6):535-539, 1993. DOI ScienceOn |
21 | Lowry, O.H., Rosenbrough, N.J., Far,r A.L., Randall, R.J. Protein measurement with the Folin phenol reagent. J Biol Chem 193(1):265-275, 1951. |
22 | Jamall, I.S., Smith, J.C. Effects of cadmium on glutathione peroxidase, superoxidase dismutase and lipid peroxidation in the rat heart: a possible mechanism of cadmium cardiotoxicity. Toxicol Appl Pharmacol 80(1):33-42, 1985. DOI ScienceOn |
23 | Pick, E., Keisari, Y. Superoxide anion and hydrogen peroxide production by chemically elicited peritoneal macrophages--induction by multiple nonphagocytic stimuli. Cell Immunol. 59(2):301-318, 1981. DOI ScienceOn |
24 | Aebi, H. Catalase. In: Bergmeyer HU (Ed.), Methods in Enzymatic Analysis. New York, Academic Press Inc., pp 673-686, 1974. |
25 | Nishikimi, M., Rao, N.A, Yagi, K. The occurrence of superoxide anion in the reaction of reduced PMS and molecular oxygen. Biochem Biophys Res Comm 46(2):849-854, 1972. DOI ScienceOn |
26 | Kakkar, P., Das, B., Viswanathan, P.N. Modified spectrophotometric assay of SOD. Indian J Biochem Biophys 21(2):130-132, 1984. |
27 | 김민성. 갑상선질환에 대한 形象醫學的연구. 大韓形象醫學會誌 9: 351-392, 2008. |
28 | O'Connor, J.C., Frame, S.R., Ladics, G.S. Evaluation of a 15-day screening assay using intact male rats for identifying steroid biosynthesis inhibitors and thyroid modulators. Toxicol Sci 69(1):79-91, 2002. DOI ScienceOn |
29 | Roti, E., Minelli, R., Gardini, E., Braverman, L.E. The use and misuse of thyroid hormone. Endocr Rev 14(4):401-424, 1993. |
30 | Yang, Y., Gordon, C.J. Regulated hypothermia in the hypothyroid rat induced by administration of propylthiouracil. Am J Physiol 272(5 Pt 2):R1390-R1395, 1997. |
31 | Carmeli, E., Bachar, A., Barchad, S., Morad, M., Merrick, J. Antioxidant status in the serum of persons with intellectual disability and hypothyroidism: a pilot study. Res Dev Disabil 29(5):431-438, 2008. DOI ScienceOn |
32 | Erdamar, H., Demirci, H., Yaman, H., Erbil, M.K., Yakar, T., Sancak, B., Elbeg, S., Biberoglu, G., Yetkin, I. The effect of hypothyroidism, hyperthyroidism, and their treatment on parameters of oxidative stress and antioxidant status. Clin Chem Lab Med 46(7):1004-1010, 2008. |
33 | Rayman, M.P., Thompson, A.J., Bekaert, B., Catterick, J., Galassini, R., Hall, E., Warren-Perry, M., Becket,t G.J. Randomized controlled trial of the effect of selenium supplementation on thyroid function in the elderly in the United Kingdom. Am J Clin Nutr 87(2):370-278, 2008. DOI |
34 | Bhanja, S., Chainy, G.B. PTU-induced hypothyroidism modulates antioxidant defence status in the developing cerebellum. Int J Dev Neurosci 28(3):251-262, 2010. DOI ScienceOn |
35 | 김동현, 김형민, 류종훈, 엄재영, 김상찬, 양재하, 조민경, 임종필, 홍승헌. 한방약리학. 서울, 신일상사, pp 186-192, 2006. |
36 | Yamamoto, M., Kumagai, A., Yamamura, Y. Structure and actions of saikosaponins isolated from Bupleurum falcatum L. I. Anti-inflammatory action of saikosaponins. Arzneimittelforschung 25(7):1021-1023, 1975. |
37 | Lin, C.C., Chiu, H.F., Yen, M.H., Wu, C.C., Chen, M.F. The pharmacological and pathological studies on Taiwan folk medicine (III): The effects of Bupleurum kaoi and cultivated Bupleurum falcatum var. komarowi. Am J Chin Med 18(3-4):105-112, 1990. DOI |
38 | Abe, H., Sakaguchi, M., Yamada, M., Arichi, S., Odashima, S. Pharmacological actions of saikosaponins isolated from Bupleurum falcatum. 1. Effects of saikosaponins on liver function. Planta Med 40(4):366-372, 1980. DOI |
39 | Yamamoto, M., Kumagai, A., Yamamura, Y. Structure and action of saikosaponins isolated from Bupleurum falcatum L. II. Metabolic actions of saikosaponins, especially a plasma cholesterol-lowering action. Arzneimittelforschung 25(8):1240-1243, 1975. |
40 | Abe, H., Sakaguchi, M., Odashima, S., Arichi, S. Protective effect of saikosaponin-d isolated from Bupleurum falcatum L. on -induced liver injury in the rat. Naunyn Schmiedebergs Arch Pharmacol 320(3):266-271, 1982. DOI ScienceOn |
41 | Hattori, T., Ito, M., Suzuki, Y. Studies on antinephritic effects of plant components in rats (1). Effects of saikosaponins original-type anti-GBM nephritis in rats and its mechanisms. Nippon Yakurigaku Zasshi 97(1):13-21, 1991. DOI ScienceOn |
42 | Sakurai, M.H., Matsumoto, T., Kiyohara, H., Yamada, H. B-cell proliferation activity of pectic polysaccharide from a medicinal herb, the roots of Bupleurum falcatum L. and its structural requirement. Immunology 97(3):540-547, 1999. DOI |
43 | 조보연. 임상갑상선학. 2판. 서울, 고려의학, pp 409-441, 2001. |
44 | 杜鎬京. 東醫腎系學. 서울, 東洋醫學硏究院, pp 729, 867-874, 1042, 1059-1065, 1993. |
45 | 송영기, 오연상. 갑상선학. 서울, 고려의학, pp 131-188, 223-247, 1995. |
46 | Devdhar, M., Ousman, Y.H., Burman, K.D. Hypothyroidism. Endocrinol Metab Clin North Am 36(3):595-615, 2007. DOI ScienceOn |
47 | Guyton, A.C. Textbook of Medical Physiology. Philadelphia, WB Saunder's Company, pp 906-908, 1986. |
48 | Surks, M.I., Ortiz, E., Daniels, G.H., Sawin, C.T., Col, N.F., Cobin, R.H., Franklyn, J.A., Hershman, J.M., Burman, K.D., Denke, M.A., Gorman, C., Cooper, R.S., Weissman, N.J. Subclinical thyroid disease: scientific review and guidelines for diagnosis and management. JAMA 291(2):228-238, 2004. DOI ScienceOn |
49 | Canaris, G.J., Manowitz, N.R., Mayor, G., Ridgway, E.C. The Colorado thyroid disease prevalence study. Arch Intern Med 160(4):526-534, 2000. DOI ScienceOn |
50 | Andreoli, T.E., Carpenter, C.J., Plum, F., Smith, L. Cecil Essentials of Medicine. Philadilphia, WB Saunder's Company, pp 436-437, 1986. |
51 | Schmidt, R.F., Thews, G. Human Physiology, Berlin Heidelberg: Springer-Verlag, pp 385-386, 1989. |
52 | 金祐謙. 內分泌.生殖. 서울, 생명의 이치, pp 60-69, 1994. |
53 | 안세영. 갑상선클리닉. 서울, 성보사, pp 132-154, 248, 2004. |
54 | Wiersinga, W.M. Thyroid hormone replacement therapy. Horm Res 56(Suppl 1):74-81, 2001. |
55 | Das, K., Chainy, G.B. Modulation of rat liver mitochondrial antioxidant defence system by thyroid hormone. Biochim Biophys Acta 1537(1):1-13, 2001. DOI ScienceOn |
56 | Subudhi, U., Das, K., Paital, B., Bhanja, S., Chainy, G.B. Supplementation of curcumin and vitamin E enhances oxidative stress, but restores hepatic histoarchitecture in hypothyroid rats. Life Sci 84(11-12):372-379, 2009. DOI ScienceOn |
57 | Sarandol, E., Tas, S., Dirican, M., Serdar, Z. Oxidative stress and serum paraoxonase activity in experimental hypothyroidism: effect of vitamin E supplementation. Cell Biochem Funct 23(1):1-8, 2005. DOI ScienceOn |
58 | Cooper, D.S. Antithyroid drugs. New Engl J Med 311: 1353-1362, 1984. DOI ScienceOn |