Browse > Article

Correlation Study between Electrogastrography and Heart Rate Variability in Dyspeptic Patients  

Kim, So-Yeon (Department of Korean Medical Science, School of Korean Medicine, Pusan National University)
Han, Chang-Woo (Department of Korean Medicine, School of Korean Medicine, Pusan National University)
Park, Seong-Ha (Department of Korean Medicine, School of Korean Medicine, Pusan National University)
Kwon, Jung-Nam (Department of Korean Medicine, School of Korean Medicine, Pusan National University)
Lee, In (Department of Korean Medicine, School of Korean Medicine, Pusan National University)
Hong, Jin-Woo (Department of Korean Medicine, School of Korean Medicine, Pusan National University)
Choi, Jun-Yong (Department of Korean Medical Science, School of Korean Medicine, Pusan National University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.26, no.4, 2012 , pp. 532-538 More about this Journal
Abstract
The aim of this study was to find correlation between EGG and HRV parameters in dyspeptic patients. 39 patients (male 8, female 31) were enrolled. EGG and HRV was measured in all patients. EGG parameters like % of gastric slow wave and power ratio were used to classify patients as normal or abnormal EGG groups. HRV parameters which were included TP (total power), LF(low frequency density), HF (high frequency density), and LF/HF ratio were compared between them. EGG parameters were compared among normal, sympathetic hyperactivity, and parasympathetic hyperactivity groups classified by LF/HF ratio. There was no difference in HRV parameters between normal and abnormal EGG groups. Comparing EGG parameters among normal, sympathetic hyperactivity, and parasympathetic hyperactivity groups, both sympathetic and parasympathetic hyperactivity groups had lower value of postprandial regularity of gastric slow wave than normal group. Abnormal value of LF/HF ratio(both sympathetic and parasympathetic hyperactivity) may be related with disturbance of electrical gastric activity in patients with dyspepsia.
Keywords
Dyspepsia; Electrogastrography(EGG); Heart rate variability(HRV); Autonomic nervous system(ANS);
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
연도 인용수 순위
1 Friesen, C.A., Lin, Z., Schurman, J.V., Andre, L., Mc Callum, R.W. Autonomic nervous system response to a solid meal and water loading in healthy children: its relation to gastric myoelectrical activity. Neurogastroenterol Motil. 19(5):376-382, 2007.   DOI   ScienceOn
2 Lipsitz, L.A., Ryan, S.M., Parker, J.A., Freeman, R., Wei, J.Y., Goldberger, A.L. Hemodynamic and autonomic nervous system responses to mixed meal ingestion in healthy young and old subjects and dysautonomic patients with postprandial hypotension. Circulation. 87(2):391-400, 1993.   DOI   ScienceOn
3 Lu, C.L., Zou, X., Orr, W.C., Chen, J.D. Postprandial changes of sympathovagal balance measured by heart rate variability. Dig Dis Sci. 44(4):857-861, 1999.   DOI   ScienceOn
4 Mazur, M., Furgala, A., Jablonski, K., Madroszkiewicz, D., Ciecko-Michalska, I., Bugajski, A., et al. Dysfunction of the autonomic nervous system activity is responsible for gastric myoelectric disturbances in the irritable bowel syndrome patients. J Physiol Pharmacol. 3: 131-139, 2007.
5 Thor, P.J., Furgala, A., Mazur, M., Posnik-Urbanska, A., Kolasinska-Kloch, W., Czarnecka, D., et al. Comparison of cardiac and gastric responses to vagal stimulation in hypertensive women. Med Sci Monit. 15(10), 2009.
6 김정룡. 김정룡 소화기계질환. 2판 ed. 서울, 일조각, pp 25-26, 2005.
7 Bharucha, A., Camilleri, M., Low, P., Zinsmeister, A. Autonomic dysfunction in gastrointestinal motility disorders. Gut. 34(3):397-401, 1993.   DOI   ScienceOn
8 Tougas, G. The autonomic nervous system in functional bowel disorders. Gut. 47(Suppl4):iv78-80, 2000.
9 Yin, J., Levanon, D., Chen, J.D. Inhibitory effects of stress on postprandial gastric myoelectrical activity and vagal tone in healthy subjects. Neurogastroenterol Motil. 16(6):737-744, 2004.   DOI   ScienceOn
10 Schurman, J.V., Friesen, C.A., Andre, L., Welchert, E., Lavenbarg, T., Danda, C.E., et al. Diagnostic utility of the water load test in children with chronic abdominal pain. J Pediatr Gastroenterol Nutr. 44(1):51-57, 2007.   DOI   ScienceOn
11 김효진, 김상헌, 이수정, 신철경, 이상희, 홍상훈, et al. HRV(Heart Rate Variability)를 통한 급성 소화불량과 만성 소화불량에 대한 자율 신경 기능 장애 비교 연구. 대한한방내과학회지 fal(1):148-156, 2008.
12 김상헌, 김효진, 이수정, 신철경, 이상희, 김원일. 심박변이도 (HRV)에서 기능성 소화불량증과 기질성 소화불량증의 상관성 연구. 대한한방내과학회지 29(2):443-455, 2008.
13 김효진, 김보경, 김원일. 심박변이도를 통한 급성, 기능성, 기질성 소화불량증의 비교연구. 동의신경정신과학회지 21(2):75-85, 2010.
14 김효진, 이수정, 이아람, 강경화, 김원일. 過心傷, 飮食傷에 따른 급성 소화불량증 환자간의 비교연구. 동의생리병리학회지 24(3):525-532, 2010.
15 임인환, 정승환, 엄은진, 이범준, 나병조. 소화불량을 主訴로 내원한 환자에서 呑酸증상 유무와 심박변이도와의 상관성 연구. 대한한방내과학회지 29(4):904-912, 2008.
16 이풍렬. 심포지엄: 소화불량증; 진단 및 관리전략: 소화불량증 환자에서 적절한 기능검사. 소화기연관학회 합동학술대회. 10(2s):24-28, 2004.
17 Van der Voort, I., Osmanoglou, E., Seybold, M., Heymann ‐Monnikes, I., Tebbe, J., Wiedenmann, B., et al. Electrogastrography as a diagnostic tool for delayed gastric emptying in functional dyspepsia and irritable bowel syndrome. Neurogastroenterology & Motility. 15(5):467-473, 2003.   DOI   ScienceOn
18 이광재, 김진홍, 함기백, 김영수, 조성원. 위전도검사로 측정된 지표들의 재현성. 대한소화기학회지 33(6):735-740, 1999.
19 지삼룡, 정혜경, 민병훈, 최기돈, 이풍렬, 강영우, et al. 기획종설: 소화기 운동 관련 질환의 치료에 관한 임상진료지침; 기 능성 소화불량증 치료에 관한 임상진료지침. 대한소화기학회지 57(2):67-81, 2011.
20 김소연, 윤상협. 기능성 소화불량증에서 위장관 미주신경 활성 평가를 위한 심박변이지표와 장음지표의 상관성 연구. 대한한방내과학회지 30(1):173-180, 2009.
21 김소연, 윤상협, 김윤범, 정승기. 기능성 소화불량증에서 위운동성 장애 진단을 위한 양도락 지표 연구. 대한한방내과학회지 29(2):401-412, 2008.
22 여형석, 임재중, 박환태. Sympathectomy 및 Vagotomy에 따른 자율신경계 변화의 관찰을 위한 HRV 스펙트럼 분석. 대한체질인류학회지 12(2):289-296, 1999.
23 Manabe, N., Nakamura, K., Hara, M., Imamura, H., Kusunoki, H., Tanaka, S., et al. Impaired gastric response to modified sham feeding in patients with postprandial distress syndrome. Neurogastroenterol Motil. 23(3):215-219, 2010.
24 Hjelland, I.E., Oveland, N.P., Leversen, K., Berstad, A., Hausken, T. Insulin-induced hypoglycemia stimulates gastric vagal activity and motor function without increasing cardiac vagal activity. Digestion. 72(1):43-48, 2005.   DOI   ScienceOn
25 Kaneko, H., Sakakibara, M., Mitsuma, T., Morise, K. Possibility of postprandial electrogastrography for evaluating vagal/nonvagal cholinergic activity in humans, through simultaneous analysis of postprandial heart rate variability and serum immunoreactive hormone levels. Am J Gastroenterol. 90(4):603-609, 1995.
26 Kobayashi, H., Ishibashi, K., Noguchi, H. Heart rate variability; an index for monitoring and analyzing human autonomic activities. Appl Human Sci. 18(2):53-59, 1999.   DOI   ScienceOn
27 Watanabe, M., Shimada, Y., Sakai, S., Shibahara, N., Matsuda, H., Umeno, K., et al. Effects of water ingestion on gastric electrical activity and heart-rate variability in healthy human subjects. J Auton Nerv Syst. 58(1-2):44-50, 1996.   DOI   ScienceOn
28 Chen, C.L., Lin, H.H., Orr, W.C., Yang, C.C., Kuo, T.B. Transfer function analysis of heart rate variability in response to water intake: correlation with gastric myoelectrical activity. J Appl Physiol. 96(6):2226-2230, 2004.   DOI   ScienceOn