Effect of Vigna angularis on Toll-like Receptor Activation and Pro-inflammatory Cytokine Production
![]() |
Kim, Mi-Hwa
(Bioindustrial Process Research Center, Bio-Materials Research Institute, Korea Research Institute of Bioscience and Biotechnology)
Jeoung, See-Hwa (Natural Bio R&D Center, Sun Bio Tech) Lee, Seung-Woong (Bioindustrial Process Research Center, Bio-Materials Research Institute, Korea Research Institute of Bioscience and Biotechnology) Kim, Hyun-Kyu (Natural Bio R&D Center, Sun Bio Tech) Park, Chan-Sun (Bioindustrial Process Research Center, Bio-Materials Research Institute, Korea Research Institute of Bioscience and Biotechnology) Jeon, Byung-Hun (Department of Pathology, College of Oriental Medicine & Research Center of Traditional Korean Medicine, Wonkwang University) Oh, Hyun-Mee (Bioindustrial Process Research Center, Bio-Materials Research Institute, Korea Research Institute of Bioscience and Biotechnology) Rho, Mun-Chual (Bioindustrial Process Research Center, Bio-Materials Research Institute, Korea Research Institute of Bioscience and Biotechnology) |
1 | Akira, S., Takeda, K., Kaisho, T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nature immunology. 2(8):675-680, 2001. DOI ScienceOn |
2 | Akira, S., Uematsu, S., Takeuchi, O. Pathogen recognition and innate immunity. Cell. 124(4):783-801, 2006. DOI ScienceOn |
3 | Hemmi, H., Takeuchi, O., Kawai, T., Kaisho, T., Sato, S., Sanjo, H., Matsumoto, M., Hoshino, K., Wagner, H., Takeda, K., Akira, S. A Toll-like receptor recognizes bacterial DNA. Nature. 408(7):740-745, 2000. |
4 | Hayashi, F., Smith, K.D., Ozinsky, A., Hawn, T.R., Yi, E.C., Goodlett, D.R., Eng, J.K., Akira, S., Underhill, D.M., Aderem, A. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature. 410(6832):1099-1103, 2001. DOI ScienceOn |
5 | Alexopoulou, L., Holt, A.C., Medzhitov, R., Flavell, R.A. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature. 413(6857):732-738, 2001. DOI ScienceOn |
6 | Lee, J., Mo, J.H., Katakura, K., Alkalay, I., Rucker, A.N., Liu, Y.T., Lee, H.K., Shen, C., Cojocaru, G., Shenouda, S., Kagnoff, M., Eckmann, L., Ben-Neriah, Y., Raz, E. Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells. Nature Cell Biology. 8(12):1327-1336, 2006. DOI ScienceOn |
7 | Takeda, K., Akira, S. Toll-like receptors in innate immunity. International Immunology. 17(1):1-14, 2005. |
8 | Rhee, S.H., Hwang, D. Murine Toll-like receptor 4 confers lipopolysaccharide responses as determined by activation of NF kappa B and expression of the induction cyclooxygenase. Journal of Biological Chemistry. 275(44):34035-34040, 2000. DOI ScienceOn |
9 | Fitzgerald, K.A., McWhirter, S.M., Faia, K.L., Rowe, D.C., Latz, E., Golenbock, D.T., Coyle, A.J., Liao, S.M., Maniatis, T. IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. Nature Immunology. 4(5):491-496, 2003. DOI ScienceOn |
10 | Curtiss, L.K., Tobias, P.S. Emerging role of Toll-like receptors in atherosclerosis. Journal of Lipid Research. Supplment(50):S340-S345, 2009. |
11 | Ariga, T., Hamano, M. Radical scavenging action and its mode in procyanidins B-1 and B-3 from azuki beans to peroxyl radicals. Agricultural Biology and Chemistry. 54: 2499-2504, 1990. DOI |
12 | Zipris, D., Lien, E., Xie, J.X., Greiner, D.L., Mordes, J.P., Rossini, A.A. TLR activation synergizes with Kilham rat virus infection to induce diabetes in BBDR rats. Journal of Immunology. 174(1):131-142, 2005. |
13 | Cook, D.N., Pisetsky, D.S., Schwartz, D.A. Toll-like receptors in the pathogenesis of human disease. Nature Immunology. 5(10):975-979, 2004. DOI ScienceOn |
14 | Trompette, A., Divanovic, S., Visintin, A., Blanchard, C., Hegde, R.S., Madan, R., Thorne, P.S., Wills-Karp, M., Gioannini, T.L., Weiss, J.P., Karp, C.L. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature. 457(7229):585-588, 2009. DOI ScienceOn |
15 | Itoh, T., Umekawa, H., Furuichi, Y. Potential ability of hot water adzuki (Vigna angularis) extracts to inhibit the adhesion, invasion and metastasis of murine B16 melanoma cells. Bioscience, Biotechnology, and Biochemistry. 69(3):448-454, 2005. DOI ScienceOn |
16 | Itoh, T., Furuichi, Y. Lowering serum cholesterol level by feeding a 40% ethanol-eluted fraction from HP-20 resin treated with hot water extract of adzuki beans (Vigna angularis) to rats fed a high-fat cholesterol diet. Nutrition. 25(3):318-321, 2009. DOI ScienceOn |
17 | Mukai, Y., Sato, S. Polyphenol-containing azuki bean (Vigna angularis) extract attenuates blood pressure elevation and modulates nitric oxide synthase and caveolin-1 expressions in rats with hypertension. Nutrition, Metabolism and Cardiovascular Diseases. 19(7):491-497, 2009. DOI ScienceOn |
18 | Kawai, T., Akira, S. Signaling to NF-kB by Toll-like receptors. Trends in Molecular Medicine. 13(11):460-469, 2007. DOI ScienceOn |
19 | Facchini, F.S., Saylor, K.L. A low-iron-available, polyphenol-enriched, carbohydrate-restricted diet to slow progression of diabetic nephropathy. Diabetes. 52(5):1204-1209, 2003. DOI ScienceOn |
20 | Mukai, Y., Sato, S. Polyphenol-containing azuki bean (Vigna angularis) seed coats attenuate vascular oxidative stress and inflammation in spontaneously hypertensive rats. The Journal of Nutritional Biochemistry. 22(1):16-21, 2011. DOI ScienceOn |
21 | Hoffman, E.S., Smith, R.E., Renaud, R.C. Jr. From the analyst's couch: TLR-targeted therapeutics. Nature review drug discovery. 4(11):879-880, 2005. DOI ScienceOn |
22 | O'Neill, L.A., Bryant, C.E., Doyle, S.L. Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer. Pharmacologicals reviews. 61(2):177-197, 2009. |
23 | 李時珍. 本草綱目. 北京. 人民衛生出版社, pp 833-837, 1456-1457, 508-512, 1982. |
24 | Ward, J.R., Francis, S.E., Marsden, L., Suddason, T., Lord, G.M., Dower, S.K., Crossman, D.C., Sabroe, I. A central role for monocytes in Toll-like receptor-mediated activation of the vasculature. Immunology. 128(1):58-68, 2009. DOI ScienceOn |
25 | Farina, C., Theil, D., Semlinger, B., Hohlfeld, R., Meinl, E. Distinct responses of monocytes to Toll-like receptor ligands and inflammatory cytokines. International Immunology. 16(6):799-809, 2004. DOI ScienceOn |
26 | Charo, I.F., Ransohoff, R.M. The many roles of chemokines and chemokine receptors in inflammation. The New England journal of medicine. 354: 610-621, 2006. DOI ScienceOn |
27 | Sato, S., Mukai, Y., Yamate, J., Kato, J., Kurasaki, M., Hatai, A., Sagai, M. Effect of polyphenol-containing azuki bean (Vigna angularis) extract on blood pressure elevation and macrophage infiltration in the heart and kidney of spontaneously hypertensive rats. Clinical and Experimental Pharmacology and Physiology. 35(1):43-49, 2008. DOI ScienceOn |
28 | Bendtzen, K. Interleukin 1, interleukin 6 and tumor necrosis factor in infection, inflammation and immunity. Immunology Letters. 19(3):183-191, 1988. DOI ScienceOn |
![]() |