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Antimicrobial Effect of Scutellariae Radix and Its Thermal Stability  

Kim, Jong-Myoung (Department of Marine Biomaterials & Aquaculture, PuKyong National University)
Lee, Chul-Won (Institute of Marine BioTechnology, Pusan National University)
Ahn, Yong-Tae (Institute of Marine BioTechnology, Pusan National University)
Lee, Ho (Beautiful Science & Technology Inc. Ltd.)
Kim, Chul (Beautiful Science & Technology Inc. Ltd.)
Kim, Hyung-Woo (School of Korean Medicine, Pusan National University)
Cho, Su-In (School of Korean Medicine, Pusan National University)
An, Won-Gun (Institute of Marine BioTechnology, Pusan National University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.26, no.3, 2012 , pp. 325-329 More about this Journal
Abstract
The present study investigated the antimicrobial properties of medicinal herbs including Scutellariae Radix (SR: dried root of Scutellariae bicalensis Georgi). Among hot-water extracts of medicinal herbs tested in this study, SR extract showed the most potent antimicrobial activity with minimum inhibitory concentration (MIC) of 0.625 mg/mL. In particular, synergistic effects of antimicrobial activity were observed upon combined application of SR and chitooligosaccharide as indicated by MIC of 0.125 mg/mL and FIC (fractional inhibitory concentration) index of 0.45. Thermal stability analysis indicated that the components responsible for antimicrobial activity was stable for 8 months at $45^{\circ}C$. Antimicrobial activity was proven to be effective in foods as well as in cosmetics as comparable to that of the chemical preservatives.
Keywords
Scutellariae Radix; Herbal medicine; antibiotics; chitooliogssaccharide;
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