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Skin Safety Evaluation of a Korean Traditional Prescription, Dansam-samul-tang and Samwhang-sasim-tang  

Lee, In-Chul (Center for Senior Industry, Youngdong University)
Kim, Bae-Hwan (Department of Public Health, Keimyung University)
Kim, Sung-Ok (Department of Surgery and the Sealy Center for Cancer Cell Biology, University of Texas Medical Branch)
Kim, Mee-Kyung (Center for Senior Industry, Youngdong University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.25, no.2, 2011 , pp. 212-216 More about this Journal
Abstract
In traditional medicines, Dansam-samul-tang and Samwhang-sasim-tang extracts were known to effects of antioxidant and antimicrobial activity. To investigate the safety evaluation of skin, these extracts were measured to skin safety testing such as primary skin irritation test, eye irritation test and skin sensitization test. The results of the primary skin irritation test and eye irritation test in vitro showed that these extracts included in the nonirritating area. Skin sensitization test results by Guinea Pig Maximization (GPMA) indicated that there was no allergy reaction. Therefore, Dansam-samul-tang and Samwhang-sasim-tang extracts were very safe in every safety test of skin. These results suggests that Dansam-samul-tang and Samwhang- sasim-tang extracts in 1 % concentration can be useful cosmetic ingredients.
Keywords
Dansam-samul-tang; Samwhang-sasim-tang; safety evaluation; skin application;
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Times Cited By KSCI : 5  (Citation Analysis)
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