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Antimicrobial Effect and Cytotoxicity of Chinensis Galla  

Kim, Seong-Jin (Department of Meridian & Acupoint, College of Oriental Medicine, Sangji University)
Yang, Ha-Young (Department of Oriental Pathology, College of Oriental Medicine, Sangji University)
Lee, Seon-Goo (Department of Oriental Pathology, College of Oriental Medicine, Sangji University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.23, no.2, 2009 , pp. 412-415 More about this Journal
Abstract
Chinensis galla has been used as an multi-functional herb, such as anti-inflammatory, anti-virus, and antitumor agent. This study was performed to antimicrobial and cytotoxicity effect in vitro. The results were summarized as follows : Chinensis galla was antimicrobial effect on Staphylococcus aureus subsp. aureus, Bacillus cereus, Bacillus subtilis, Staphylococcus epidermidis. Chinensis galla was antimicrobial effect on Kocuria rhizophila, Corynebacterium ammoniagenes. The extracts of Chinensis galla exhibited cytotoxicity on human dermal fibroblast at $10\;{\mu}{\ell}$ but not at $5\;{\mu}{\ell}$, and the same results was known under a microscope. Accordingly the results show Chinensis galla could antimicrobial effect but exhibited cytotoxicity on human dermal fibroblast at high concentration and it needs more research.
Keywords
chinensis galla; skin flora; pitted keratolysis; antimicrobial; cytotoxicity;
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Times Cited By KSCI : 4  (Citation Analysis)
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