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Effect of Water Extract from Artemisiae Argi Folium on Hydrogen Peroxide Production within Mouse Macrophage Raw 264.7 Cells Treated with Gallic acid, EtOH, LPS, and Acetaminophen  

Park, Wan-Su (Department of Pathology, College of Oriental Medicine, Kyungwon University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.22, no.6, 2008 , pp. 1495-1499 More about this Journal
Abstract
The purpose of this study is to investigate the effect of water extract from Artemisiae Argi Folium (WAAF) on hydrogen peroxide production within mouse macrophage Raw 264.7 Cells treated with gallic acid, EtOH, LPS, and acetaminophen. WAAF (0${\sim}$400 ug/mL) was treated with gallic acid, EtOH, LPS, acetaminophen. And the intracellular productions of hydrogen peroxide were measured by dihydrorhodamine 123 (DHR) assay. WAAF showed the restoration of the intracellular productions of hydrogen peroxide which were reduced by gallic acid, EtOH, LPS, and acetaminophen in Raw 264.7 Cells. WAAF could be supposed to have the immunological activity related with macrophage's oxidative burst.
Keywords
macrophage; immuno activity; Artemisiae Argi Folium; hydrogen peroxide; gallic acid;
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