Protective Effect of the Herbal Combination HCE-2 on Alcohol Metabolism and Alcohol-induced Liver Injury in Ethanol-loaded Rats |
Han, Dong-Oh
(Acupuncture & Meridian Science Research Center, Kyung Hee University)
Park, Soo-Jin (The Graduate School of East-West Medical School, Kyung Hee University) Sur, Bong-Jun (Acupuncture & Meridian Science Research Center, Kyung Hee University) Lee, Hye-Jung (Acupuncture & Meridian Science Research Center, Kyung Hee University) Kim, Sung-Hoon (Department of Pathology, College of Oriental Medicine, Kyung Hee University) Hahm, Dae-Hyun (Acupuncture & Meridian Science Research Center, Kyung Hee University) |
1 | Marjanen, L. Intracellular localization of aldehyde dehydrogenase in rat liver. Biochem. J. 127: 663-639, 1972 |
2 | Lieber, C.S., DeCarli, L.M. Hepatic microsomal ethanol oxidizing system: In vitro characteristics and adaptive properties in vivo. J. Biol. Chem. 245: 2505-2512, 1970 |
3 | Kim, K.W., Yang, J.S., Lee, J.S., Cho, Y.S., Kang, S.K., Chung, H.K. Activity of alcohol dehydrogenase and ethanol, acetaldehyde levels in normal adults blood. Korean Indus. Hyg. Assoc. J. 4: 240-247, 1994 |
4 | Abdellah, M., Demelliers, C., Amsellem, S., Pessayre, D., Fromenty, B. Acute ethanol administration oxidatively damages and depletes mitochondrial DNA in mouse liver, brain, heart, and skeletal muscles: protective effects of antioxidants. J. Pharmacol. Exp. Ther. 298: 737-743, 2001 |
5 | Mosmann, T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J. Immunol. Method. 65: 55-63, 1983 DOI |
6 | Lieber, C.S. Alcohol and the liver: Metabolism of ethanol, metabolic effects and pathogenesis of injury. Acta. Med. Scand. (Suppl). 703: 11-55, 1985 |
7 | French, S.W. Biochemical basis for alcohol-induced liver injury. Clin. Biochem. 22: 41-49. 1989 DOI ScienceOn |
8 | Lieber. C.S. Hepatic, metabolic and toxic effects of ethanol.Clin. Exp. Res. 15: 573-592. 1991 DOI ScienceOn |
9 | Kim, H.S., Kim, Y.G., Son, H.J. Effect of Pueraria lobataextract water on the ethanol metabolism enzyme activities in ethanol administered rats. J. Agri. Tech. & Dev. Inst. 3: 219-225, 1999 |
10 | Murray, R.K., Granner, D.K., Mayes, P.A., Rodwell, V.W. Lipids. In: Harper's Biochemistry. Connecticut: Appleton & Lange. 260, 1993 |
11 | 김창민,,신민규, 안덕균, 이경순 外. 完譯中藥大辭典, (주)鼎談, 2: 582-587, 7: 3500-3506, 8: 3938-3939, 1999 |
12 | Nordmann, R., Ribiere, C., Rouach, H. Implication of free radical mechanisms in ethanol-induced cellular injury. Free Radic. Biol. Med. 12: 219-240, 1992 DOI ScienceOn |
13 | Zimmerman, H.J. Chemical hepatic injury and its detection: In toxicology of the liver. New York, Raven press. pp 1-10, 1981 |
14 | Lieber, C.S. Ethanol metabolism, cirrhosis and alcoholism. Clin. Chem. Acta. 257(1):59-84, 1997 DOI ScienceOn |
15 | Wheeler, M.D., Nakagami, M., Bradford, B.U., Uesugi, T., Mason, R.P., Connor, H.D., Dikalova, A., Kadiiska, M., Thurman, R.G. Overexpression of manganese superoxide dismutase prevents alcohol-induced liver injury in the rat. J. Biol. Chem. 276: 36664-36672, 2001 DOI ScienceOn |
16 | 본초학. 전국한의과대학 본초교수 공 편저. 도서출판 영림사, pp 169-170, 1991 |
17 | Burk, R.F., Hill, K.E., Awad, J.A., Morrow, J.D., Kato, T., Cockell, K.A., Lyons, P.R. Pathogenesis of diquat-induced liver necrosis in selenium-deficient rats. Assessment of the roles of lipid peroxidation by measurement of F2isoprotanes. Hepatology. 21: 561-569, 1995 |
18 | Gill, K., Amit, Z., Smith, B.R. The regulation of alcohol consumption in rats: the role of alcohol, metabolizing enzymes, catalase and aldehyde dehydrogenase. Alcohol. 13(4): 347-355, 1996 DOI ScienceOn |
19 | Jin-Taek Kim, Dong-Hoan Kim, Sang-Hyun Ahn. The effect of chronic alcohol administration to alteration of liver, kidney and stomach in mouse. The Journal of Dong Guk Oriental Medicine 3: 163-169, 1994 |