Browse > Article

Antioxidative Activity and Nitrite Scavenging Ability of Methanol Extract from Ricinus communis  

Kang, Jeong-Il (Department of Physical Therapy, College opf Complementary and Alternative Medicine, Jeonju University)
Lim, Jin-A (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.21, no.3, 2007 , pp. 666-670 More about this Journal
Abstract
Efficacy of antioxidative activity and nitrite scavenging ability of methanol extract from Ricinus communis. was investigated. Electron-donating ability of extract at RC$_{50}$ was 114.02 ${\mu}g$/mL. After addition of 0.46 mg/mL extract, autoxidation of pyrogallol decreased to 32.99% by superoxide dismutase-like activity. In antioxidative activity of extract against linoleic acid during incubation times of 24, 48, 96 hours at 40$^{\circ}C$, lipid peroxidation values significantly decreased by 85.50%, 87.77%, 90.95% with addition of 0.2 mg/mL, respectively. Total phenolic content was determined as gallic acid equivalents (GAE) and values revealed 83.98 ${\pm}$ 5.66 GAE ${\mu}g$/mg of extract. Nitrite scavenging ability showed the most remarkable effect at pH 1.2, decreasing to 47.24% by addition of 0.2 mg/mL. These results suggest that methanol extract from Ricinus communis. can be used as bioactive and functional material.
Keywords
Ricinus communis; Antioxidative activity; Nitrite scavenging ability;
Citations & Related Records
Times Cited By KSCI : 10  (Citation Analysis)
연도 인용수 순위
1 Kim, S.J., Han, D.S. Effect of Plants Extracts on Lipid peroxidation of rat brain tissue induced by reactive oxygen species. Korean J. Food Sci. Technol. 37(6):976-982, 2005   과학기술학회마을
2 Hah, D.S., Kim, C.H., Kim, G.S., Kim, E.G., Kim, J.S. Antioxidant effects of traditional medicinal plants on lipid peroxidation. Korean J Vet Res. 45(3):341-350, 2005
3 김창민, 신민교, 안덕균, 이경순 외. 중약대사전, 도서출판정담, p 1886, 1997
4 Woo, B.H., Lee, J.T., Lee, K.C. Purification of sepharose- unbinding ricin from Castor Beans (Ricinus communis) by hydroxyapatite chromatography. Protein Expression and Purification 13(2):150-154, 1998   DOI   ScienceOn
5 Yoon, J.O. Studies on the preparation of food proteins from caster bean protein. Korean J. Food Sci. Technol. 12: 263-271, 1980
6 Ismail, M., Manickam, E., Danial, A.M., Rahmat, A., Yahaya, A. Chemical composition and antioxidant activity of Strobilanthes crispus leaf extract. J. Nutr. Biochem. 11(11-12):536-542, 2000   DOI   ScienceOn
7 Slinkard, K., Singleton, V.L. Total phenol analysis: automation and comparison with manual methods. Am. J. Enology and Viticulture. 28: 49-55, 1977
8 Kwak, C.S., Lim, S.J., Kim, S.A., Park, S.C., Lee, M.S. Antioxidative and antimutagenic effects of korean buckwheat, sorghum, millet and jpb's tears. J. Korean Soc. Food Sci. Nutr. Lee. 33(6):921-929, 2004   DOI
9 Dinis, T.C.P., Madeira, V.M.C., Almeida, L.M. Action of phenolic derivates (acetoaminophen, salycilate and 5-aminosalycilate) as inhibitors of membrane lipid peroxidation and as peroxyl radical scavengers. Arch. Biochem. Biophys. 315: 161-169, 1994   DOI   ScienceOn
10 Hayes, R.E., Bookwalter, G.N., Bagley, E.B. Antioxidant activity of soybean flour and derivatives. J. Food Sci. 6: 1527-1532, 1997
11 Mirvishm, S.S. Formation of N-nitro compounds: Chemistry, kinetics and in vivo oxxurrence. Toxicol. Appl. Pharmacol. 31: 325-351, 1975   DOI   ScienceOn
12 Raju, I., Moni, M., Subramanian, V. Anti-inflammatory and free radical scavenging activity of Ricinus communis root extract. Journal of Ethnopharmacology 103(3):478-480, 2006   DOI   ScienceOn
13 Lee, S.H., Jin, Y.S., Heo, S.I., Shin, T.H., Sa, J.H., Choi D.S., Wang, M.H. Composition analysis and antioxidative activity from different organs of Cir Korea J. Food SCI. Technol. 38(4):571-576, 2006   과학기술학회마을
14 Lim, J.A., Na, Y.S., Baek, S.H. Antioxidant activity and nitrite scavenging ability of ethanol extract from Phyllostachys bambusoides. Korean J. Food Sci. Technol. 36(2):306-310, 2004
15 Kim, N.Y. Choi, J.H. Kim, Y.G., Jang, M.Y., Moon, J.H., Park, G.H., Oh, D.H. Isolation and identification of an antioxidant substance from ethanol extract of wild grape (Vitis coignetiea) seed. Korea J. Food SCI. Technol. 38(1):109-113, 2006   과학기술학회마을
16 Choi, S.Y., Chung, M.J., Shin, J.H., Kim, H.J., Sung, N.J. Effect of green tea(Camellia sinensis) and maesil(Prunus mume) extracts on endogenous formation of N-Nitrosodimethylamine. 15(1):16-22, 2002
17 Challoner, K.R., McCarron, M.M. Castor bean intoxication. Annals of Emergency Medicine. 19: 1177-1183, 1990   DOI   ScienceOn
18 Sung, K.C. A study on the pharmacetical characteristics &　analysis of glycyrrhizin extract. J. of Korean Oil Chemists' Soc. 23(3):215-222, 2006   과학기술학회마을
19 Heo, J.C., Park, J.Y., An, S.M., An, S.M., Lee, J.M., Yun, C.Y., Shin, H.M., Kwon, T.K., Lee, S.H. Anti-oxidant and anti-tumor activities of crude extracts by Gastrodia elata Blume. 13(1):83-87, 2006
20 Masaru, F. Toxic Protein 'Ricin' of Ricinus communis. Korean J. Food Sci. Technol. 11: 206-208, 1979
21 Lee, J.H., Lee, S.R. Analysis of phenolic substance content in Korean plant foods. Korean J. Food Sci. Thechnol. 26: 310-316, 1994
22 Han, S.H., Woo, N.R.Y., Lee, S.D., Kang, M.H. Antioxidative and antibacterial activities of endemic plants extracts in Korea. Korean J. Medicinal Crop Sci. 14(1):49-55, 2006   과학기술학회마을
23 Blois, M.S. Antioxidant determination by the use a stable free radical. Nature. 26: 1199-1200, 2006
24 Park, C.S., Kwon, C.J., Choi, M.A., Park, G.S., Choi, K.H. Antioxidative and nitrite scavenging activities of mugwort and pine needle extracts. Korean Journal of Food Preservation 9(2):248-252, 2002
25 Kim, S.C., Ahn, K.S., Park, C.K., Jeon, B.S., Lee, J.T., Park, W.J. Isolation of antioxidative compound from Scutellaria baicalensis G. Korean J. Medicinal Crop Sci. 14(4):212-216, 2006   과학기술학회마을
26 Simmons, B.M., Russel, J.H. A single affinity column step method for the purification of ricin toxin from caster beans (Ricinus communis). Anal. Biochem. 146: 206-210, 1985   DOI   ScienceOn
27 Lee, S.E., Son, D.W., Yoon, Y.P., Lee, S.Y., Lee, B.J. Lee, S.H. Protective Effect of the Methanol Extracts of Acanthopanax koreanum against Oxidative Stress. Kor. J. Pharmacogn. 37(1):16-20, 2006   과학기술학회마을
28 Hwang, E.J., Lee, S.Y., Kwon, S.J., Park, M.H., Boo, H.O. Antioxidative, antimicrobial and cytotoxic activities of fagopyrum esculentum moench extract in germinated seeds. Korean J. Medicinal Crop Sci. 14(1):1-7, 2006   과학기술학회마을
29 Marklund, S., Marklund, G. Involvement of superoxide anion radical in the oxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur. J. Biochem. 47: 468-474, 1974
30 Kato, H., Lee, I.E., Chyuen, N.V., Kim, S.B., Hayase, F. Inhibitory of nitrosamine formation by nondialyzable melanoidins. Agric. Biol. Chem. 51(1):1333-1338, 1987   DOI
31 Kang, Y.H., Park, Y.K., Lee, G.D. The nitrite scavenging and electron donationd ability of phenolic compound. Korean J. Food Sci. Technol. 28: 232-239, 1996
32 Park, C.S., Kwon, C.J., Choi, M.A., Park, G.S., Choi, K.H. Antioxidative and nitrite scavenging activities of Cordyceps militaris extracts. Korean Journal of Food Preservation. 9(1):109-113, 2002
33 Gray, J.I., Dugan, Jr L.R. Inhibition of N-nitrosamine formation in model food systems. J. Food Sci. 40: 981-984, 1975   DOI
34 An, B.J., Park, J.M., Bae, H.J., Pyun, J.R. Song, M.A. Antioxidant and antibacterial effects of Koream isodon japonicus H. J. Korean Soc. Appl. Biol. Chem. 49(2):129-134, 2006   과학기술학회마을