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Effects of Gami-Daehwangmokdan-tang on the Gout Induced ICR Mice  

Eom, Hyun-Sup (Department of Orintal Pathology, College of Oriental Medicine, Dongeui Univiersity)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.21, no.2, 2007 , pp. 399-403 More about this Journal
Abstract
In order to obtain practical application of Daehwangmokdan-tang gout disease, water extract of Gami-daehwangmokdan-tang(GDMT) added with Lonicera japonica is prepared through decoction and freeze drying. The effects were evaluated with blood sample from ICR mice treated with MSU intra-peritoneal injection 1 time a day, 3 days consecutively. The results were as follows. GDMT decreased BUN, creatinine and C-reactive protein level in serum significantly. But the HDL and LDL cholesterol levels were not changed in spite of positive tendency in HDL cholesterol. Triglyceride and uric acid levels were decreased significantly too. These results show that GDMT can be used effectively against the urate-related gout disease.
Keywords
Gami-daehwangmokdan-tang; Uric acid level; Lonicera japonica;
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