1 |
Bertrand, C.P. and P.D. Ponath CCR3 blockade as a new therapy for asthma. Expert opinion on investigational drugs 9, 43-52, 2000
DOI
ScienceOn
|
2 |
Bevan, M.A., Metzger, H. Signal transduction by FC receptors: the FceRI case. Immunol Today 14, 222-226, 1993
DOI
ScienceOn
|
3 |
Boguniecwicz, M., Schneider, L.C., Milgrom, H., Newell, D., Kelly, N., Tam Izu, P., AE, Jaffe, H.S., Bucalo, L.R., Leung, D.Y.M. Treatment of steroid-dependent asthma with recombinant interferon-. Clin. Exp. Allergy 23, 785-790, 1993
DOI
ScienceOn
|
4 |
Walsh, G.M., Al-Rabia, M., Blaylock, M.G., Sexton, D.W., Duncan, C.J., Lawrie, A. Control of eosinophil toxicity in the lung. Curr Drug Targets Inflamm Allergy. 4, 481-486, 2005
DOI
ScienceOn
|
5 |
Cho, S.H., Seo, J.Y., Choi, D.C., Yoon, H.J., Cho, Y.J., Min, K.U., Lee, G.K., Seo, J.W., Kim, Y.Y. Pathologic changes according to the severity of asthma. Clin Exp Allergy 26, 1210-1219, 1996
DOI
ScienceOn
|
6 |
Corrigan, C.J., Hartnell, A., Kay, A.B. T-lymphocyte activation in acute severe asthma. Lancet 1, 1129-1132, 1988
|
7 |
Elias, J.A., Zhu, Z., Chupp, G., Homer, R.J. Airway remodeling in asthma. J Clin Invest. 104, 1001-1006, 1991
DOI
|
8 |
Hershey, G.K. IL-13 receptors and signaling pathways: an evolving web. J Allergy Clin Immunol 111, 677-690, 2003
DOI
ScienceOn
|
9 |
Holgate, S.T., Frew, A.T., Howarth, P.H. T-cell cytokine profile evaluated at the single cell level in BAL and blood in allergic asthma. Am J Respir Cell Mol Biol 14, 319, 1996
DOI
ScienceOn
|
10 |
Kelly-Welch, A.E., Melo, M.E., Smith, E., Ford, A.Q., Haudenschild, C., Noben-Trauth, N. Keegan AD. Complex role of the IL-4 receptor alpha in a murine model of airway inflammation: expression of the IL-4 receptor alpha on nonlymphoid cells of bone marrow origin contributes to severity of inflammation. J Immunol. 172, 4545-4555, 2004
DOI
|
11 |
Nishikubo, K., Murata, Y., Tamaki, S., Sugama, K., Imanaka-Yoshida, K., Yuda, N., Kai, M., Takamura, S., Sebald, W., Adachi, Y., Yasutomi, Y. A single administration of interleukin-4 antagonistic mutant DNA inhibitsallergic airway inflammation in a mouse model of asthma. Gene Ther 10, 2119-2125, 2003
DOI
ScienceOn
|
12 |
Robinson, D.S., Ying, S., Bentley, A.M., Meng, Q., North, J., Durham, S.R., Kay, A.B., Hamid, Q. Relationships among numbers of bronchoalveolar lavage cells expressing mRNA for cytokines, asthma symptoms, and airway methacholine responsiveness in atopic asthma. J Allergy Clin Immunol 92, 397-403, 1993
DOI
ScienceOn
|
13 |
Westergren-Thorsson, G., Chakir, J., Lafreniere-Allard, M.J., Boulet, L.P., Tremblay, G.M. Correlation between airway responsiveness and proteoglycan production by bronchial fibroblasts from normal and asthmatic subjects, Int. J. Biochem. Cell. Biol. 34, 1256-1267, 2002
DOI
ScienceOn
|
14 |
Marone, G. Asthma: recent advandes. Immunol. Today 19, 5-9, 1998
DOI
ScienceOn
|
15 |
Kay, A.B. Asthma and inflammation. J. Allergy Clin. Immunol. 87, 893-910, 1991
DOI
|
16 |
McMillan, S.J., Lloyd, C.M. Prolonged allergen challenge in mice leads to persistent airway remodelling. Clin Exp Allergy. 34, 497-507, 2004
DOI
ScienceOn
|
17 |
Lichenstein, L.M. Allergy and the Immune system. Sci Am (Sept):116-124, 1993
|
18 |
Ying, S., Durham, S.R., Humbert, M., Barkans, J. Expression of IL-4 and IL-5 mRNA and protein product by and T-cells, eosinophils and mast cells in bronchial biopsies obtained from atopic and non-atopic (intrinsic) asthmatics. J Immunol. 158, 3539-3544, 1997
|
19 |
Blanc, P.D., Trupin, L., Earnest, G., Katz, P.P., Yelin, E.H., Eisner, M.D. Alternative therapies among adults with a reported diagnosis of asthma orrhinosinusitis: data from a population-based survey. Chest 120, 1461-1467, 2001
DOI
|
20 |
Laitinen, L.A. mA. Laitinen and T. Haahtela. Airway mucosal inflammation even in patients with newly diagnosed asthma, Am Rev Respir Dis 147, pp 697-704, 1993
DOI
ScienceOn
|
21 |
Maggi, E., Parronchi, P., Manetti, R. et al. Reciprocal regulatory effects of IFNgamma and IL-4 on the in vitro development of human Th1 and Th2 clones. J. Immunol 148, 2142-2147, 1992
|
22 |
Wiley, R.E., Cwiartka, M., Alvarez, D., Mackenzie, D.C., Johnson, J.R., Goncharova, S., Lundblad, L., Jordana, M. Transient corticosteroid treatment permanently amplifies the Th2 response in a murine model of asthma. J Immunol. 172, 4995-5005, 2004
DOI
|
23 |
Sempowski, G.D., Beckmann, M.P., Derdak, S., Phipps, R.P. Subsets of murine lung fibroblasts express membrane-bound and soluble IL-4receptors. Role of IL-4 in enhancing fibroblast proliferation and collagen synthesis. J Immunol. 152, 3606-3614, 1994
|
24 |
Lack, G., Bradely, K.L., Hamelmann, E., Renz, H., Loader, J., Leung, D.Y.M., Larsen, G., Gelfand, E.W. Nebulized IFN- inhibits the development of secondary allergic responses in mice. J Immunol 157, 1432-1429, 1996
|
25 |
Egashira, Y. and Nagano, H. A multicenter clinical trial of TJ-96 in patients with steroid-dependent bronchial asthma. Ann N Y Acad Sci 685, pp 580-583, 1993
DOI
ScienceOn
|
26 |
Kong, X.-T., Fang, H.T., Jiang, G.Q., Zhai, S.Z., O'Connell, D.L. and Brewster, D.R. Treatment of acute bronchiolitis with Chinese herbs. Arch Dis Child 68, pp 468-471, 1993
DOI
ScienceOn
|
27 |
Izuhara, K. The role of interleukin-4 and interleukin-13 in the non-immunologic aspects ofasthma pathogenesis. Clin Chem Lab Med 41, 860-864, 2003
DOI
ScienceOn
|
28 |
Kazi, A.S., Lotfi, S., Goncharova, E.A., Tliba, O., Amrani, Y., Krymskaya, V.P. Lazzar, A.L., Vascular endothelial growth factor-induced secretion of fibronectin is ERK dependent, Am. J. Physiol. 286, L539-L545, 2004
|
29 |
Todd, G.K., Dunlop, J., McNaboe, M.F., Ryan, D., Carson and M.D. Shields, Growth and adrenal suppression in asthmatic children treated with high-dose fluticasone proprionate, Lancet 348, 27-29, 1996
DOI
ScienceOn
|
30 |
Brightling, C.E., Symon, F.A., Holgate, S.T., Wardlaw, A.J., Pavord, I.D., Bradding, P. Interleukin-4 and -13 expression is co-localized to mast cells within the airway smooth muscle in asthma. Clin Exp Allergy 33, 1711-1716, 2003
DOI
ScienceOn
|
31 |
Look, D.C., Rapp, S.R., Keller, B.T., Holtzman, M.J. Selective induction of intercellular adhesion molecule-1 by interferon-gamma in human airway epithelial cells. Am. J. Physiol. 263, L79, 1992
|
32 |
Tufvesson, E. and G. Westergren-Thorsson, Biglycan and decorin induce morphological and cytoskeletal changes involving signalling by the small GTPases RhoA and Rac1 resulting in lung fibroblast migration, J. Cell. Sci. 116, 4857-4864, 2003
|
33 |
Cockcroft, D.W. Pharmacologic therapy for asthma: overview and historical perspective. J Clin Pharmacol 39, 216-222, 1999
|
34 |
Kelly-Welch, A.E., Hanson, E.M., Boothby, M.R., Keegan, A.D. Interleukin-4 and interleukin-13 signaling connections maps. Science 300, 1527-1528, 2003
DOI
|
35 |
Pene, J., Rousset, F., Briere, F., Chreitien, I., Bonnefoy, J.Y., Spits, H., Yokota, T., Arai, N., Arai, K.I. , Banchereau, J., de Vries, J.E. IgE production by normal human lymphocytes is induced by interleukin-4 and suppressed by interferons- and - and prostaglandin E2. Proc. Natl. Acad. Sci. U.S.A. 85, 6880-6884, 1988
|
36 |
Izuhara, K., Arima, K., Yasunaga, S. IL-4 and IL-13: their pathological roles in allergic diseases and theirpotential in developing new therapies. Curr Drug Targets Inflamm Allergy 1, 263-269, 2002
DOI
ScienceOn
|
37 |
Krug, N., Madden, J., Redington, A.E., Lackie, P., Djukanovic, R., Schauer, U., Holgate, S.T., Frew, A.T., Howarth, P.H. T-cell cytokine profile evaluated at the single cell level in BAL and blood in allergic asthma. Am J Respir Cell Mol Biol 14, 319-326, 1996
DOI
ScienceOn
|
38 |
Elias, J. Inspirations on asthma. J Clin Invest. 104, 827-828, 1999
DOI
|
39 |
Postlethwaite, A.E., Holness, M.A., Katai, H., Raghow, R. Human fibroblasts synthesize elevated levels of extracellular matrix proteinsin response to interleukin 4. J Clin Invest. 90, 1479-1485, 1992
DOI
|
40 |
Adams, G.K. 3d, Lichtenstein, L.M., Adkinson NF Jr. Effects of dexamethasone on mediator release from human lung fragments, and purified human lung mast cells. J Clin Invest 71, 1830-1835, 1983
DOI
|
41 |
Sampson, AP. The role of eosinophils and neutrophils in inflammation. Clin Exp Allergy. 30 Suppl 1, 22-27, 2000
DOI
ScienceOn
|
42 |
Fireman, P. Understanding asthma pathophysiology. Allergy Asthma Proc 24, 79-83, 2003
|
43 |
Corrigan, C.J., Kay, A.B. CD4 T-lymphocyte activation in acute severe asthma. Am. Rev. Respir. Dis. 141, 970, 1990
DOI
ScienceOn
|
44 |
Del Prete, G.F., De Carli, M., D'Elios, M.M., Maestrelli, P., Ricci, M., Fabbri, L., Romagnani, S. Allergen exposure induces the activation allergen-specific Th2-cells in the airrway mucosa of patients with allergic respiratory disorders. Eur J Immunol 23, 1445-1449, 1993
DOI
ScienceOn
|
45 |
Kay, A.B., Frew, A.J., Corrigan, C.J., Robinson, D.S. The T-cell hypothesis of chronic asthma. In kay AB ed. Allergy and allergic diseases. Blackwell Science, 1997
|
46 |
Hsieh, K.H. Evaluation of efficacy of traditional Chinese medicines in the treatment of childhood bronchial asthma: clinical trial, immunological tests and animal study. Pediatr Allergy Immunol 7, pp 130-140, 1996
DOI
|
47 |
Bochner, B.S., Schleimer, R.P. The role of adhesion molecules in human eosinophil and basophil recruitment.J Allergy Clin Immunol. 94, 427-438, 1994
DOI
ScienceOn
|
48 |
Bradley, B.L., Azzawi, M., Jacobson, M., Assoufi, B., Collins, J.V., Irani, A.M., Schwartz, L.B., Durham, S.R., Jeffery, P.K., Kay, A.B. Eosinophils, T-lymphocytes, mast cells, neutrophils and macrophages in bronchial biopsy specimens from atopic subjects with asthma; comparison with biopsy specimens from atopic subjects witout asthma and normal control subjects and relationship to bronchial hyperresponsiveness. J Allergy Clin Immunol 88, 661-674, 1991
DOI
|