Browse > Article

Effect of Ganyangsanghang-bang on Hypertension  

Han, Deok-Hee (Department of Internal Medicine, College of Oriental Medicine)
Oh, Young-Seon (Hyehwa Hospital, Daejeon University)
Seol, In-Chan (Department of Internal Medicine, College of Oriental Medicine)
Kim, Yoon-Sik (Department of Internal Medicine, College of Oriental Medicine)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.20, no.3, 2006 , pp. 663-669 More about this Journal
Abstract
This study was done to investigate the effect of Ganyangsanghang-bang(GYSHB) on hypertension. After administering GYSHB extract to SHR for 5 weeks, changes in blood pressure, pulse rate, aldosterone and catecholamine levels in plasma were examined, and immunohistochemical changes were observed, and liver function test was done. The following results were obtained; blood presure decreased significantly as well as levels of aldosterone and norepinephrine in SHR. But levels of dopamine were unaffected. No capillary vessel dilation in adrenal cortex was observed. Safety against hepatic toxicity was showed. These results support a role for GYSHB might be usefully applied in treatment of hypertension.
Keywords
Ganyangsanghang-bang(GYSHB); Hypertension;
Citations & Related Records
연도 인용수 순위
  • Reference
1 의학교육연수원 편. 가정의학. 서울, 서울대학교출판부, pp 294-299, 1999
2 張元昌 外. 實用中醫內科學(下), 北京, 人民衛生出版社, 1981, p 1530
3 上海中醫學院 편. 中醫內科學, 商務印書館, p 150, 1977
4 林俊植. 滲濕湯이 高血壓 및 高脂血症에 미치는 影響. 大田大學校 大學院 韓醫學科碩博論考, 2, 337-339, 1999
5 韓承東. 大柴胡湯加味方이 高血壓 및 高脂血症에 미치는 影響. 慶山大學校 大學院, 1999
6 이원로. 임상심장학. 서울, 고려의학, pp 479-481, 1998
7 이영우 외. 고혈압. 서울, 고려의학, pp 11-55, 2000
8 屈松柏 外. 實用中醫心血管病學. 北京, 科學技術文獻出版社, pp 347-354, 1993
9 JNC. Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure, December 1, 2003
10 申皇秀. 加味導赤散이 高血壓에 미치는 影響. 大田大學校 大學院, 2004
11 趙顯慶. 導痰湯이 腦損傷 및 高血壓에 미치는 影響. 大田大學校 大學院, 2001
12 兪炳巑. 加味鷄血藤湯이 高血壓에 미치는 影響. 大田大學校 大學院, 2004
13 Walter, F., Emile, L. medical physiology, saunders, pp 534-545, 1057-1061, 2003.
14 Eugene, Braunwald, Stephen L., Anthony, S., Dan, L., Dennis, L., J. Larry Jameson. harrison's principles of internal medicine 15th edition, McGrawHill, pp 1414-1430, 2001
15 대한내과학회 해리슨내과학 편집위원회 편. 해리슨내과학 제1권. 서울, 도서출판 MIP, pp 1456-1461, 2003
16 김영석 외. 고혈압에 대한 임상적 관찰. 대한한의학회지, 4(2):321-331, 1983
17 이기상 외. 瀉心湯이 白鼠의 血壓 및 局所 腦血流量에 미치는 影響. 大韓韓醫學會誌 21(3):417-424, 2000
18 김정진. 생리학. 서울, 고문사, pp 115-118, 1997
19 이영우. 순환기학. 서울, 일조각, pp 93-195, 205, 2001
20 김기훈, 문재우. 공중보건학. 서울, 정문각, pp 373-347, 1999
21 金鍾仁. 地黃飮子가 腦損傷 및 高血壓에 미치는 影響. 大田大學校 大學院, 2001
22 서울대학교 의과대학 편. 내분비학. 서울, 서울대학교출판부, pp 199, 203-204, 1994