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Antifungal Activity of (-)-ent-Costunolide on the Dermatophytic Fungus Trichophyton mentagrophytes  

Kim, Myung-Ju (Department of Skin & Beauty, Kwangju Health Science College)
Baek, Seung-Hwa (Department of Herbal Resources, Professional Graduate School of Oriental Medicine and Institute of Basic Natural Sciences, Wonkwang University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.20, no.2, 2006 , pp. 467-470 More about this Journal
Abstract
Bioactivity directed isolation has led to the isolation of (-)-ent-costunolide (1) as the major active compound. This compound (1) inhibited the growth of the dermatophytic fungus Trichophyton mentagrophytes ATCC 28185, (4 mm inhibition zone at $15\;{\mu}g/disc$).
Keywords
(-)-ent-costunolide (1); Trichophyton mentagrophytes; Antifungal activity;
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