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Antioxidant effects of the Root of Vitis labrusca Water and Aqua-acupuncture Solution  

Lim Seong-Cheorl (Cardiovascular Medical Research Center and Dept. of AM-Pointology, College of Oriental Medicine, Dongguk University)
Moon Jin-Young (Cardiovascular Medical Research Center and Dept. of AM-Pointology, College of Oriental Medicine, Dongguk University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.20, no.1, 2006 , pp. 76-82 More about this Journal
Abstract
This study was purposed to investigated the antioxidant effects of water (VLWS) and aqua-acupuncture solution (VLAS) from root of Vitis labrusca. VLWS and VLAS was were assessed to determine the mechanisms of its antioxidant activities. The VLWS and VLAS exhibitde a concentration-dependent inhibition of DPPH free radicals. This VLWS-mediated antioxidant activity was similar to that L-ascorbic acid (vitamin C). In addition, the VLWS and VLAS showed dose-dependent free radical scavenging activity, including superoxide anions and hydroxyl radicals, using different assay systems. The VLWS and VLAS were also found to be strongly inhibited linoleic acid oxidation in a ferric thiocyanate assay (FTC) system. Finally, the VLWS and VLAS significantly prevented Fenton's reagent-induced DNA nicking.
Keywords
Vitis labrusca root (葡萄根); antioxidant; free radicals; deoxyribose;
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