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Study on the Polyphosphate content of the Yukmijihwang-tang and its Effect on transcription activity of Genes related to Bone Morphogenesis  

Park Byung Chul (Department of oriental Rehabilitation Medicine, College of Oriental Medicine, Sang-ji University)
Cha Yun Yeop (Department of oriental Rehabilitation Medicine, College of Oriental Medicine, Sang-ji University)
Lee Eung Se (Department of oriental Rehabilitation Medicine, College of Oriental Medicine, Sang-ji University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.18, no.6, 2004 , pp. 1769-1776 More about this Journal
Abstract
The aim of this study was to find out the effects of the Yukmijihwangtang on transcription activity of Genes related to Bone Morphogenesis. For this purpose, experiments were performed to compare the polyphosphate contents of Yukmijihwangtang and its component herbs, and to verify their Effects on transcription activity of Genes related to Bone Morphogenesis. We know that Yukmijihwangtang and its component herbs have adequate amount of polyphosphate contents and have effects on transcription activity of Genes such as BMP1A, BMP2B, OTN, MGP, COL. In the conclusion, Yukmijihwangtang and its component herbs are strongly believed to have effectiveness on bone morphogenesis.
Keywords
Yukmijihwang-tang; Bone Morphogenesis; polyphosphate;
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