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Comparative Study of Nitric Oxide Scavenging Effect in Several Herbal Extracts  

Yoo Yeong Min (Department of Biology, College of Natural Science, Kangwon National University, Department of Oriental Pathology, College of Oriental Medicine, Sangji University)
Lee Seon Goo (Department of Oriental Pathology, College of Oriental Medicine, Sangji University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.18, no.5, 2004 , pp. 1512-1515 More about this Journal
Abstract
In this study, we investigated in vitro nitric oxide (NO) scavenging effect on nine herbal extracts using an NO donor S-nitroso-N-acetylpenicillamine (SNAP) compared with vitamin C. All herbal extracts effectively reduced the generation of NO radicals in a dose-dependant manner and over 65% in 10h. Especially, Ephedrae herba, Carthami flos and Lonicerae flos declined over 75% of NO scavenging effect, suggested that the herbal extracts are the powerful free radical scavengers and may be effective in clinical applications.
Keywords
nitric oxide; S-nitroso-N-acetylpenicillamine; Griess reagent; antioxidant;
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Times Cited By KSCI : 1  (Citation Analysis)
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