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Biological Activity of Water Extract from Atractylodes macrocephala

Chun Ju Yeon (Department of Dental Hygjene, Wonkwang Health Science College, Wonkwang University)
Lee Hyun Ok (Department of Dental Hygjene, Wonkwang Health Science College, Wonkwang University)
Baek Seung Hwa (Department of Herbal Resources, Professional Graduate School of Oriental Medicine and Institute of Basic Natural Sciences, Wonkwang University)

Publication Information

Journal of Physiology & Pathology in Korean Medicine / v.18, no.2, 2004 , pp. 596-598 More about this Journal

Abstract

The effects of water extract from Atractylodes macrocephala Koidz on biological activity were investigated. The crude water extract of A. macrocephala inhibited the growth of the dermatophytic fungus Trichophyton mentagrophytes ATCC 28185, (3 mm inhibition zone at 300 ㎍/disc). However, it did not show growth inhibition activity against Sreptococcus mutans JC-2 (MIC >1,000 ㎍/mL). This extract was cytotoxic to P388 murine leukaemia cells ATCC CCL 46 P388D1, (IC/sub 50/ 62.24 ㎍/mL at 150 ㎍/disc). These results suggest that water extract of A. macrocephala possesses antitumoral, and antimicrobial activities.

Keywords

Atractylodes macrocephala; Trichophyton mentagrophytes; antimicrobial activity;

Citations & Related Records

Times Cited By KSCI : 1 (Citation Analysis)

Reference
Cited By KSCI

1	/ [] / Pharmacopoeia of Peoples Republic of China
2	Antiinflammatory principles of Atractylodes rhizomes / [ Endo, K.;Taguchi, T.;Taguchi, F.;Hikino, H.;Yamahara, J.;Fujimura, H. ] / Chem. Pharm. Bull. DOI
3	The acetylenes from Atractylodes macrocephala / [ Chen, Z. L. ] / Planta Med.
4	A novel bisesquiterpenoid, biatractyloide, from the Chinese herbal plant Atractylodes macrocephala / [ Lin, Y.;Jin, T.;Wu, X.;HuangM Z.;Fan, J.;Chan, W. L. ] / J. Nat. Prod.
5	Screening of cytotoxicity and antimicrobial effects of extracts form Atractylodes macrocephala Koidz / [ Choi, E. Y.;Oh, H. J.;Park, N. K,;Chun, H. J.;Ahn, J. W.;Jeon, B. H.;Han, D. S.;Lee, H. O.;Baek, S. H. ] / Kor. J. Orien. Physiol. & Pathol.
6	Synthesis and bological effects of acyclic pyrimidine nucleoside analogues / [ Schroeder, A. C.;Hughes, R. G. Jr.;Bloch, A ] / J. Med. Chem. DOI
7	Rapid colorimetric assays for cellular growth and survival; application of proliferation and cytotoxicity assays / [ Mosmann, T ] / J. Immunol. Methods DOI
8	Evaluation of a tetrazolium based semiautomated colorimetric assay; Assessment of chemo-sensitivity testing / [ Carmichael, J.;Degraff, W. G.;Grazdr, A. F.;Minna, J. D.;Mitchell, J. B ] / Cancer Res.
9	Pharmacological screening of crude extracts from medicinal plants (I) / [ Oh, H. J.;Kwag, J. S.;Kim, M. J.;Perry, N. B.;Kim, H. M.;Baek, S. H. ] / Kor. J. Orien. Physiol. & Pathol.
10	Inhibitory effects of ethanol extract of Atractylodes Rhizoma alba on melanin biosynthesis / [ Chun, H. J.;Choi, E. Y.;Yoon, S. C.;Nam, H. W.;Baek, H. B.;Woo, W. H. ] / J. Pharm. Soc.