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Antifungal Activity of 4-Geranyloxy Compound on the Dermatophytic Fungus

Oh Hyun Ju (Department of Herbal Resources, Professional Graduate School of Oriental Medicine and Institute of Basic Natural Sciences, Wonkwng University)
You Byung Soo (Division of Natural Sciences, Wonkwng University)
Kim Myung Ju (Department of Skin & Beauty, Kwangju Health Science College,)
Na Young Soon (Division of Fashion & Beauty, Konyang University)
Kim Hyung Min (Department of Pharmacology, School of Oriental Medicine, Kyunghee University)
Baek Seung Hwa (Department of Herbal Resources, Professional Graduate School of Oriental Medicine and Institute of Basic Natural Sciences, Wonkwng University)

Publication Information

Journal of Physiology & Pathology in Korean Medicine / v.18, no.2, 2004 , pp. 575-579 More about this Journal

Abstract

4-Geranyloxy compound (1) has elucidated by spectroscopic analysis. This compound (1) inhibited the growth of the dermatophytic fungus Trichophyton mentagrophytes ATCC 28185, (2 mm inhibition zone at 15 ㎍/disc), cytotoxic to P388 murine leukaemia eel/lines ATCC CCL 46 P388D1, (IC/sub 50/ 1,125 ng/ml at 7.5㎍/disc) and BSC monkey kidney cell lines (100% of well at 15 ㎍/disc).

Keywords

4-Geranyloxy compound(1); Trichophyton mentagrophytes; P388; cytotoxic activity;

Citations & Related Records

Reference

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