Induction of Cdk Inhibitor p21 and Inhibition of hTERT Expression by the Aqueous Extract of Wikyung-tang in Human Lung Carcinoma Cells
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Choi Hae-Yun
(Pohang Oriental Hospital of Daegu Haany University, Dongeui University College of Oriental Medicine and Research Institute of Oriental Medicine)
Park Cheol (Department of Biochemistry, Dongeui University College of Oriental Medicine and Research Institute of Oriental Medicine) Choi Yung Hyun (Department of Biochemistry, Dongeui University College of Oriental Medicine and Research Institute of Oriental Medicine) Park Dong Il (Department of Internal Medicine, Dongeui University College of Oriental Medicine and Research Institute of Oriental Medicine) |
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Premature p34cdc2 activation required for apoptosis.
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Multiple pathways to apoptosis
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Apoptosis. The role of the endonuclease.
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Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis
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Mammalian G1 cyclins.
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Cyclin A is required for the onset of DNA replication in mammalian fibroblasts
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A link between cyclin A expression and adhesion- dependent cell cycle progression
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Role for cyclin A in the dependence of mitosis on completion of DNA replication
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Cdk inhibitors: on the threshold of checkpoints and development
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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
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Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit
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p21 is a universal inhibitor of cyclin kinases
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Complex regulatory mechanisms of telomerase activity in normal and cancer cells: How can we apply them for cancer therapy
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Activity, function, and gene regulation of the catalytic subunit of telomerase (hTERT)
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葦莖湯·加味葦莖湯의 A549에 대한 세포독성과 S-180에 대한 항암효과
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Proteolytic cleavage of phospholipase C-gamma1 during apoptosis in Molt-4 cells
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Apoptosis-induced cleavage of -catenin by caspase-3 results in proteolytic fragments with reduced transactivation potential
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Studies of inositol phospholipid-specific phospholipase C
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Overexpression of phospholipase C-1 in rat 3Y1 fibroblast cells leads to malignant transformation
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Activation of phosphatidylinositol 3-kinase is important for erythropoietin-induced erythropoiesis from CD34(+) hematopoietic progenitor cells
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p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
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Bcl-2 prolongs cell survival after Bax- induced release of cytochrome c
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Bcl-2 functions in an antioxidant pathway to prevent apoptosis
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Principles of CDK regulation
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DNA damage-induced cell cycle checkpoints involve both p53- dependent and -independent pathways: role of telomere repeat binding factor 2
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Telomeres, telomerase, and myc. An update
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Apoptosis and the cell cycle
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WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis
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Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
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Significance of cell cycle and checkpoint control.
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The Pezcoller lecture: cancer cell cycles revisited.
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D-type cyclin-dependent kinase activity in mammalian cells
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Identification of G1 kinase activity for cdk6, a novel cyclin D partner.
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Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle
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Cyclin-dependent regulation of G1 in mammalian fibroblasts
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Evaluation of in vitro chemosensitivity using human lung cancer cell lines
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Ayurvedic herbal drugs with possible cytostatic activity.
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Yama/CPP32 , a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
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Specific proteolytic cleavage of poly (ADP-ribose) polymerase: an early marker of chemotherapy- induced apoptosis
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Cleavage of poly ADP-ribose polymerase by a proteinase with properties like ICE
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Cell adhesion molecules in the development and progression of malignant melanoma
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E-cadherin- catenin cell-cell adhesion complex and human cancer.
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Induction of apoptosis by ursolic acid through activation of caspases and down-regulation of c-IAPs in human prostate epithelial cells
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The role of the E-cadherin/catenin complex in gastrointestinal cancer
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Apoptosis-associated cleavage of -catenin in human colon cancer and rat hepatoma cells
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ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase
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The proteolysis of mitotic cyclins in mammalian cells persists from the end of mitosis until the onset of S phase
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