[KSCI] Korea Science Citation Index Service

Effect of Sabaek-san on the Immunomodulatory Action 사백산의 면역조절 효과

Cho Seoung Yeoun (Department of Pathology, College of Oriental Medicine, Woosuk University)
Lee Dong Joe (Department of Pathology, College of Oriental Medicine, Woosuk University)
Jeong Han Sol (Department of Pathology, College of Oriental Medicine, Woosuk University)
Lee Sang Ryong (Department of AM-Pointology, College of Oriental Medicine, Woosuk University)
Lee Kwang Gyu (Department of Pathology, College of Oriental Medicine, Woosuk University)

Publication Information

Journal of Physiology & Pathology in Korean Medicine / v.18, no.1, 2004 , pp. 63-68 More about this Journal

Abstract

The purpose of this research was to investigate the effect of Sabaek-San(SBS) on the activity of immune cell and leukemia cell. The addition of SBS(1 ㎍/㎖) enhanced the proliferation of cultured-splenocytes and thymocytes. And also, administration of SBS(250, 500 mg/kg) accelerated subpopulation of splenic T lymphocytes in BALB/c mice. Administration of SBS eminently enhanced the production of IFN-γ, and IL-4. The treatment of high dose of SBS inhibit the proliferation of Jurkat cells and dose-dependently increased the apoptosis of cultured-Jurkat leukemia cells. These results suggest that SBS have a cell mediated immuno-regulatory effect.

Keywords

Sabaek-San(瀉白散); IFN-γ; immonoregulatory;

Citations & Related Records

Times Cited By KSCI : 1 (Citation Analysis)

Reference
Cited By KSCI

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