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Pharmacological Screening of Crude Extracts from Medicinal Plants (I)

Oh Hyun Ju (Department of Herbal Resources, Professional Graduate School of Oriental Medicine and Institute of Basic Natural Sciences, Wonkwang University)
Kwag Jung Sook (Department of Dental Hygiene, Mokpo Science College)
Kim Myung Ju (Department of Skin & Beauty, Kwangju Health Science College)
Perry Nigel B. (Plant Extracts Research Unit, New Zealand Institute for Crop & Food Research Ltd,)
Na Young Soon (Department of Chemistry, Otago University)
Kim Hyung Min (Division of Fashion & Beauty, Kyung Hee University, Department of Pharmacology, Kyung Hee University)
Baek Seung Hwa (Department of Herbal Resources, Professional Graduate School of Oriental Medicine and Institute of Basic Natural Sciences, Wonkwang University)

Publication Information

Journal of Physiology & Pathology in Korean Medicine / v.18, no.1, 2004 , pp. 250-253 More about this Journal

Abstract

The effects of crude extracts from medicinal plants on biological activity were investigated. The crude ethanol extract of H. paucistipula inhibited the growth of the Gram positive bacterium Bacillus subtilis ATCC 19659, (2 mm inhibition zone at 150 ㎍/disc) and the dermatophyte Trichophyton mentagrophytes ATCC 28185, (7 mm inhibition zone at 150 ㎍/disc), and toxic to P388 murine leukaemia cells ATCC CCL 46 P388D1, (IC/sub 50/ 2.48 ㎍/㎖ at 75 ㎍/disc). This crude ethanol extract of H. paucistipula is the strongest antimicrobial and cytotoxic activities against P388 murine leukaemia cells ATCC CCL 46 P388D1.

Keywords

Brachyglottis monroi; Trichocolea hatcheri; Hepatostolonophora paucistipula; Bacillus subtilis; Trichophyton mentagrophytes; P388; Cytotoxic activity;

Citations & Related Records

Reference

1	Screening for biological activity of crude extract and fractions from Brachyglottis monroi / [ Baek, S. H.;Lim, J. A.;Kwag, J. S.;Lee, H. O.;Chun, H. J.;Lee, J. H.;Perry, N. B. ] / Kor. J. Orien. Physiol. & Pathol.
2	/ [ Allison, K. W. ] / The Liverworts of New Zealand
3	Name changes in the indigenous New Zealand flora, 1960 - 1986 and Nomina Nova IV, 1983 - 1986 / [ Connor, H. E.;Edger, E. ] / New Zealand J. Bot.
4	/ [ Allan, H. H. ] / Flora of New Zealand
5	/ [ Riley, M. ] / Maori Healing and Herbal
6	/ [ Asakawa, Y.;Herz, W.;Kirby, G. W.;Moore, R. E.;Steglich, W.;Tamm, C.(Eds.) ] / In progress in the Chemistry of Organic Natural Products
7	Synthesis and biological effects of acyclic pyrimidine nucleoside analogues / [ Schroeder, A. C.;Hughes, R. G. Jr.;Bloch, A. ] / J. Med. Chem. DOI
8	Rapid colorimetric assays for cellular growth and survival: application to proliferation and cytotoxicity assays / [ Mosmann, T. ] / J. Immunol. Methods DOI