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Effects of Ginseng Radix and Ophiopogonis Tuber on Field Potentials in Rat Hippocampal and Cardiac Muscle Slices  

Lee Choong Yeol (Department of Physiology, College of Oriental Medicine, Kyungwon University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.17, no.6, 2003 , pp. 1463-1467 More about this Journal
Abstract
In the present study, the effects of Ginseng radix and Ophiopogonis tuber on field potentials in rat hippocampal slices and cardiac muscle slices were investigated by multi-channel extracellular recording using MED64 system. The field potentials in the brain slices represent synaptic transmission and nerve excitability, and the field potentials in heart muscles represent muscle contractility. The present results show that the aqueous extract of Ginseng radix enhanced field potentials in the both hippocampal slices and cardiac muscle slices. In contrast, the aqueous extract Ophiopogonis tuber exerted no significant effect on the field potentials in the hippocampal slices and cardiac muscle slices. These results suggest the possibility that Yin-Yang theory could be studied in relation with excitability in neurons and muscles.
Keywords
Ginseng radix(人蔘); Ophiopogonis tuber(麥門冬); field potential; hippocampus; cardiac muscle;
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