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Inhibitory Effects on the Type I hypersensitivity and Inflammatory Reaction of Sogunjung-tang  

Jung Il Hong (Department of Oriental Medicine, Graduate School, Dongeui University)
Kim Ji Yun (Department of Oriental Medicine, Graduate School, Dongeui University)
Kam Chul woo (Department of Oriental Medicine, Graduate School, Dongeui University)
Park Dong il (Department of Oriental Medicine, Graduate School, Dongeui University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.17, no.5, 2003 , pp. 1188-1193 More about this Journal
Abstract
Sogunjung-tang(SGJT) has been used for the treatment of general weakness, digestive organ disease and so on. This study was carried out for the purpose of knowing the inhibitory effect on the Type I hypersensitivity and Inflammatory reactions of SGJT. The reasults were obtained as follows: SGJT(0.1, 0.5, 1, 2mg/g) concentration of dependently inhibited compound48/80 induced anaphylaxis reaction in mice. SGJT(2mg/g) also inhibited permeability of evans blue into peritoneal cavity in mice. SGJT reduced IgE, CRP, WBC and Platelets on egg albumin induced hypersensitivity. but serum NO was grown. According to above results, SGJT may be beneficial in the type I hypersensitivity and Inflammatory reactions by inhibition of histamine release from mast cells.
Keywords
Sogunjung-tang(小建中湯); egg albumin; Anaphylaxis; Acetic acid;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
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