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Immunoregulatory Effects of Gungchihwadam-jeon and Cheongsinhwadam-jeon  

Kim Lak Hyun (College of Oriental medicine, Woosuk University)
Kwon Jin (Department of Health Administration, Kunjang College)
Lee Kwang Gyu (College of Oriental medicine, Woosuk University)
Jeong Han Sol (College of Oriental medicine, Woosuk University)
Oh Chan Ho (Division of Biotechnology, Woosuk University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.17, no.4, 2003 , pp. 1097-1100 More about this Journal
Abstract
This study was performed to evaluate the immunoregulatory effects of Gungchihwadam-Jeon(궁치화담전, GCHDJ) and Cheongsinhwadam-Jeon(청신화담전, CSHDJ) was administered(p.o.) once a day for 14 days to mice. By the treatment of GCHDJ or CSHDJ was increased the cell viability of cultured mice splenocytes, thymocytes and mesenteric lymph node cells. Administration of GCHDJ or CSHDJ was increased the splenic T lymphocyte, especially the Tc cell subpopulation was increased by the GCHDJ, on the while the TH cell was increased by the CSHDJ. The administration of GCHDJ or CSHDJ was significantly increased the apoptosis of transplanted-L1210 leukemia cells to mice peritoneal cavity. These results suggest that GCHDJ and CSHDJ have an immunoregulatory action
Keywords
Gungchihwadam-Jeon(芎梔化痰煎); Cheongsinhwadam-Jeon(淸神化痰煎); splenocytes; thymocytes; mesenteric lymph node cells; L1210 leukemia cells; apoptosis;
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