Induction of Apoptotic Cell Death by Insamsapye-tang Extract in Human Lung Cancer A549 Cells |
Park Cheol
(Department of Biochemistry, and Internal Medicine, College of Oriental Medicine, Dongeui University)
Lee Min Woo (Research Institute of Oriental Medicine, College of Oriental Medicine, Dongeui University) Kim Won Il (Research Institute of Oriental Medicine, College of Oriental Medicine, Dongeui University) Lee Won Ho (Department of Biology, College of Natural Sciences, Busan National University) Park Dong Il (Research Institute of Oriental Medicine, College of Oriental Medicine, Dongeui University) Choi Yung Hyun (Department of Biochemistry, and Internal Medicine, College of Oriental Medicine, Dongeui University) |
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Yama/CPP32, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase.
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Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c.
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Bcl-2 functions in an antioxidant pathway to prevent apoptosis.
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4 |
Cyclooxygenase-2: a therapeutic target.
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5 |
COX-2 inhibition and prevention of cancer.
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6 |
Is COX-2 inhibition a panacea for cancer prevention?
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7 |
Cyclooxygenase-2: a novel target for cancer chemotherapy?
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8 |
Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals:down-regulation of COX-2 and iNOS through suppression of NF-kB activation.
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9 |
Cox-2, iNOS and p53 as play-makers of tumor angiogenesis.
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10 |
Cyclooxygenase inhibitors suppress angiogenesis and reduce tumor growth in vivo.
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11 |
Nonsteroidal anti-inflammatory drugs as anticancer agents: mechanistic, pharmacologic, and clinical issues.
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12 |
Induction of apoptosis by ursolic acid through activation of caspases and down-regulation of c-IAPs in human prostate epithelial cells.
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13 |
Multiple pathways to apoptosis.
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14 |
Premature p34cdc2 activation required for apoptosis.
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Apoptosis and the cell cycle.
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WAF1/CIPl is induced in p53-mediated G1 arrest and apoptosis.
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Tumor suppressor p53 is a direct transcriptional activator of the human bax gene.
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20 |
Induction of Cdk inhibitor p27 and inhibition of pRB phosphorylation by Insamsapye-tang treatment in human lung cancer A549 cells
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22 |
The effects of Yunpyesan on cell proliferation, apoptosis and cell cycle progression of human lung cancer A549 cells
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23 |
Tetrandrine-induced cell cycle arrest and apoptosis in A549 human lung carcinoma cells.
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24 |
Research technics for the cell cycle study
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25 |
Apoptotic activity of novel bile acid derivatives in human leukemic T cells through the activation of caspases.
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26 |
Induction of apoptotic cell death by sabaeksan extract in human lung cancer. A549 cells
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27 |
The machinery of programmed cell death.
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28 |
Necrosis and apoptosis in acute renal failure.
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29 |
Cleavage of poly ADP-ribose polymerase by a proteinase with properties like ICE.
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30 |
Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis.
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31 |
The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis.
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32 |
E-cadherin-catenin cell-cell adhesion complex and human cancer.
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33 |
The role of the E-cadherin/catenin complex in gastrointestinal cancer.
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34 |
Apoptosis. The role of the endonuclease.
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35 |
Regulation of cyclin D1 by calpain protease.
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