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The Effects of Kamichungsangboha-tang on the Respiratory Patterns and Tracheal Tissues in Allergic Asthma  

Woo Young Sik (Department of Oriental Medicine, Graduate School, Dongeui University)
Kim Jin Il (Department of Oriental Medicine, Graduate School, Dongeui University)
Kang Pil Koo (Department of Oriental Medicine, Graduate School, Dongeui University)
Park Dong Il (Department of Oriental Medicine, Graduate School, Dongeui University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.16, no.6, 2002 , pp. 1217-1222 More about this Journal
Abstract
This study was aimed to find out Kami-Chungsangboha-tang's effects on allergic asthma using Egg-White Implant(EWI) method model recommended by Siqueira et al. Kami-Chungsangboha-tang has widely been prescribed and used in Oriental Medicine for controlling and curing of the symptoms of Asthma(dyspnea, wheezing, cough, sputum, chest discomfort). The Previous studies have demonstrated that Kami-Chungsangboha-tang had analgesic, sedative, anticonvulsive and antihistamine effects. But it was uncertain whether Kami-Chungsangboha-tang could inhibit the allergic reaction, so alleviate the symptoms of allergic asthma. With such aim, the respiratory patterns and eosinophil infiltration in the tracheal mucosa of rats with experimentally induced allergic asthma (using EWI method) were mainly observed. The results are as follows ; 1. Kami-Chungsangboha-tang decreased the number of malformed respiration with respect to control group (p<0.02). 2. Kami-Chungsangboha-tang decreased the number of eosinophils infiltrated in tracheal mucosa with respect to control group (p<0.05). Depending upon above results, it is considered that Kami-Chungsangboha-tang has the inhibitory effects on the process of allergic asthma and suggested that it could be used in relieving patients of the symptoms caused by allergic asthma.
Keywords
Kami-Chungsangboha-tang(加味淸上補下湯); asthma; respiratory patterns;
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