[KSCI] Korea Science Citation Index Service

Effect of Silsosangami on Neutrophil Functions and Cyclo-oxygenase-2

Kim Chang Hwan (Department of Diagnostics, College of Oriental Medicine, Dongguk University)
Park Won Hwan (Department of Diagnostics, College of Oriental Medicine, Dongguk University)

Publication Information

Journal of Physiology & Pathology in Korean Medicine / v.16, no.5, 2002 , pp. 1048-1054 More about this Journal

Abstract

Silsosangami(SSG) is a formula of oriental medicines as an effective biological response modifier for augmenting host homeostasis of body circulation. Also SSG has been known to have an anti-diabetic activity and anti-platelet aggregation activity. The present study was undertaken to examine the effects of a new SSG on murine macrophage and human neutrophil functions as well as on several enzymes relevant to the inflammatory process. The results of the present study indicate that SSG exerts anti-inflammatory effects related to the inhibition of neutrophil functions and of PGE2 production, which could be due to a decreased expression of and COX-2.

Keywords

Silsosangami(失笑散加味); prostaglandin; cyclooxygenase; neutrophils;

Citations & Related Records

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