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Effect of Kamidaebo-tang on Murine Peritoneal Macrophages  

Song Jung Mo (Department of Oriental Medicine, Woosuk University)
Oh Chan Ho (College of Science and Technology, Woosuk University)
So June No (College of Science and Technology, Woosuk University)
Kim Dae Keun (College of Pharmacy, Woosuk University)
Eun Jae Soon (College of Pharmacy, Woosuk University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.16, no.5, 2002 , pp. 1020-1024 More about this Journal
Abstract
The purpose of this research was to investigate the effects of Kamidaebo-tang water extract (KDT) on murine peritoneal macrophages. KDT (50 or 250 mg/kg) was administerd p.o. once a day for 7 days to mice. KDT increased the production of tumor necrosis factor-α and nitric oxide from murine peritoneal macrophages, but decreased the production of interleukin-1β. Also, KDT enhanced the production of lucigenin chemiluminescence from peritoneal macrophages. These results suggest that KDT enhances the non-specific immune response via increase of tumor necrosis factor-α and nitric oxide and phagocytic activity from peritoneal macrophages.
Keywords
Kamidaebo-tang(加味大補湯); cytokine; peritoneal macrophage; phagocytosis;
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  • Reference
1 Effect of Insamyangyoung-tang on the specific immune response in BALB/c mice. /
[ Eun, J.S.;Kim, D.K.;Choi, H.;Oh, C.H. ] / Kor. J. Oriental Physiology & Pathology
2 加味大補湯이 생쥐의 免疫調節作用에 미치는 영향 /
[ 李鍾年 ] / 大田大學校大學院 博士學位論文
3 Killing of Plasmodium faciparum in vitro by nitric oxide derivatives. /
[ Rockett, K.A.;Awburn, M.M.;Cowden, W.B.;Clark, I.A. ] / Infec. Immunity
4 Chemiluminenscence and nitrite determinations by the MALU macrophage cell line. /
[ Boudard, F.;Vallot, N.;Cabaner, C.;Bastide, M. ] / J. Immunol. Methods
5 Measure- ment of phagocyte chemiluminenscence in a microtiter plate format. /
[ Blair, A.L.;Cree, I.A.;Beck, J.S.;Hating, M.J.G. ] / J. Immunol. Methods
6 A rapid and simple microfluorometric phagocytosis assay. /
[ Chok, P.W.;Choon, S.P.;Benjamin, H.S. ] / J. Immuno. Methods
7 Zymosan-stimulated production of phosphatidic acid by macrophages: relationship to release of superoxide anion and inhibition by agents that increase intracellular cyclic AMP. /
[ Channon, J. Y.;Leslie, C. C.;Johnston, Jr. R. B. ] / J. Leucocyte Biol.
8 Nitric oxide prevents IL-1<TEX>$\beta$</TEX> and IFN-<TEX>$\gamma$</TEX>-inducing gactor(IL-18) release from macrophages by inhibiting caspase-1(IL-1<TEX>$\beta$</TEX>-converting enzyme). /
[ Kim, Y.M.;Talanian, R.V.;Li, J.;Billiar, T.R. ] / J. Immunology
9 Overproduction of nitric oxide in cytokine-mediated and septic shock. /
[ Kilbourn, R.G.;Griffith, O.W. ] / J. Natl. Cancer Instit.
10 Intra- and extracellular evevts in luminol-dependent chemiluline- scence of polymorphonuclear leukocytes. /
[ Breiheim, G.;Stendahl, O.;Dahlgren, C. ] / Infect. Immun.
11 /
[ Abbas, A. K.;Lichtman, A. H.;Pober, J. S. ] / Cellular and molecular immunology.
12 Nitric oxide inhibits macrophage pseudopodia formation in the activated macrophages. /
[ Jun, C.D.;Park, S.K.;Kim, J.M.;Kim, J.D.;Kim, S.H. ] / Kor. J. Immunol.
13 /
[ 陳師文 ] / 太平惠民和劑局方
14 /
[ 大田大學校 韓方病院 ] / 韓方病院 處方集
15 /
[ 李尙仁 ] / 本草學
16 /
[ 李尙仁 ] / 漢藥臨床應用
17 四君子湯이 생쥐의 免疫反應 및 NK 細胞의 細胞毒性에 미치는 영향 /
[ 李南九(外) ] / 大韓韓醫學會誌
18 八物湯이 抗癌 및 免疫調節作用에 미치는 영향 /
[ 河智容 ] / 大韓東醫病理學會誌
19 人蔘養榮湯의 抗癌 및 免疫調節作用에 미치는 영향 /
[ 河智容(外) ] / 大韓東醫病理學會誌