[KSCI] Korea Science Citation Index Service

Effect of the Concurrent Administration of Banhasasim-tang with Cimetidine on Gastric Ulcer in Rats

Lee Kwang Gyu (College of Oriental Medicine, Woosuk University)
Cui Xun (Department of Oriental Pharmacy, Woosuk University)
Lim Jong Pil (Department of Oriental Pharmacy, Woosuk University)

Publication Information

Journal of Physiology & Pathology in Korean Medicine / v.16, no.3, 2002 , pp. 572-576 More about this Journal

Abstract

Banhasasim-tang(半夏瀉心湯), oriental medicine, has been used for the treatment of the gastric diseases and cimetidine, H2-receptor blocker, has been also used as the gastric ulcer remedy but has some side action. Therefore the concurrent administration of these two drugs may increase antiulcer activities and also decrease cimetidine's side action more than administrating one by one. In order to investigate antiulcer activities, some experiments were conducted. The concurrent administration of Banhasasim-tang extract(BS) and cimetidine(CM) given intraperitoneally (CM 50mg/kg + BS 300mg/kg and CM 50mg/kg + BS 500 mg/kg), significantly inhibited Shay, aspirin and indomethacin ulcers in rats.

Keywords

Banhasasim-tang(半夏瀉心湯); cimetidine; Shay; aspirin; indomethacin; ulcers;

Citations & Related Records

Reference

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KSCI

Effect of the Concurrent Administration of Banhasasim-tang with Cimetidine on Gastric Ulcer in Rats 반하사심탕과 씨메티딘의 작용투여가 흰쥐의 위궤양에 미치는 영향

Effect of the Concurrent Administration of Banhasasim-tang with Cimetidine on Gastric Ulcer in Rats