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Effects of Shudihuang Water Extracts on the cGMP Production and Receptors for Atrial Natriuretic Peptide in the Kidney in Rats  

Lee Ho Sub (Department of Physiology, College of Oriental Medicine, Wonkwang University)
Yu Yun Cho (Department of Physiology, College of Oriental Medicine. Woosuk University)
Publication Information
Journal of Physiology & Pathology in Korean Medicine / v.16, no.3, 2002 , pp. 490-494 More about this Journal
Abstract
The purpose of this study is to investigate the effect of Shudihuang water extracts on the cGMP production of medulla and cortical membranes, receptors for atrial natriuretic peptide in the kidney by in vitro autoradiography in rats for 8, 16 weeks. The cGMP production of medullary and cortical membranes of the kidney decreased after the administration of Shudihuang water extracts. The density of receptors for atrial natriuretic peptide in the kidney decreased after the administration of Shudihuang water extracts only for 16 weeks. These results suggest that the long term administration of Shudihuang water extracts has decreased plasma renin activity and plasma levels of aldosterone modulated cGMP production of medullary and cortical membranes, density of receptors for atrial natriuretic peptide in the kidney.
Keywords
Shudihuang(熟地黃); cGMP production; vitro autoradiography;
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  • Reference
1 Effects of Rhemanniae Radix water extract on the renal function and renin secretion rate in unanesthetized rabbits /
[ Lee, H. S.;S. T. Kim;K. C. Cho ] / American Journal of Chinese Medicine
2 /
[ 宋鍾燦 ] / 心兪, 腎兪 鍼刺가 人體의 血漿 Atrial Natriuretic Peptide, <TEX>$\beta$</TEX>-Endorphin, Aldosterone, Cortisol 및 Renin 活性度에 미치는 影響
3 八味丸과 六味丸의 臨床應用例 /
[ 安正華;高學敏 ] / 東洋醫學
4 植物生藥의 angiotensin 變換酵素 抑制作用檢索 /
[ 尹惠淑;鄭聖顯;韓秉勳 ] / 大韓生藥學會誌
5 /
[ 魯鎭求 ] / 熟地黃 煎湯液과 附子 煎湯液 投與가 白鼠의 腎臟機能과 血漿 Renin 活性度 및 ANP 濃度에 미치는 影響
6 /
[ 杜鎬京 ] / 東醫腎系學(上)
7 /
[ 朴呈培 ] / 地黃 水鍼이 實驗的 腎性 高血壓 白鼠의 腎臟 機能에 미치는 影響
8 地黃 煎湯液 投與가 白鼠의 血漿 Renin 活性度, 血漿 Aldosterone 및 ANP 濃度에 미치는 影響 /
[ 兪閏朝;李昊燮 ] / 大韓韓醫學會誌
9 Regional expression of natriuretic peptide receptors during the formation of arterial neointima in the rabbit /
[ Brown, J;Chen, Q ] / Circ Res.
10 水火相濟에 대한 文獻的 考察 /
[ 兪閏朝;李光揆;陸相元 ] / 東醫生理學會誌
11 /
[ 姜斗熙 ] / 生理學
12 신동맥내 투여한 Angiotensin Ⅱ가 신장기능 및 Renin 분비에 미치는 영향 /
[ 김종훈;강남부;김영진;김선희;조경우 ] / 대한생리학회지
13 /
[ 이인모 ] / 인체생리학
14 /
[ 심문균;이정수;김시현 ] / 인체생리학
15 /
[ 李彦政 ] / 六味地黃湯 煎湯液이 腎性 高血壓 白鼠의 血壓 및 血漿 renin 活性度에 미치는 影響
16 /
[ 金炯均 ] / 左歸飮과 六味地黃湯 煎湯液 投與가 家兎 腎臟機能 및 血漿 Aldosterone濃度에 미치는 影響
17 /
[ 申佶求 ] / 申氏本草學
18 /
[ 金完熙 ] / 臟腑辨證論治
19 /
[ 鄭銀卿 ] / 六味地黃湯과 八味地黃湯 煎湯液 投與가 白鼠의 腎臟機能, 血漿 Renin 活性度, Aldosterone 및 ANP 濃度에 미치는 影響
20 /
[ 陸昌洙 ] / 韓藥學 Ⅱ
21 藥針이 自發性 高血壓 白鼠의 血壓 및 腎臟機能에 미치는 影響 /
[ 邊宰煐;兪閏朝;李昊燮;金庚植 ] / 大韓針灸學會志